TERBINAFINE HCL, USP 100GM by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name TERBINAFINE HCL USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) 1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-, monohydrochloride;(2E)-N,6,6- Trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine hydrochloride (1:1) Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Skin corrosion/irritation Category 2,Serious eye damage/eye irritation Category 2A,Acute aquatic toxicity category 1, Chronic aquatic toxicity category 1 Signal Word Warning Hazard Statement(s) H315 Causes skin irritation H319 Causes serious eye irritation H410 Very toxic to aquatic lif e with long lasting ef f ects Pictogram(s) Precautionary Statement(s) P264 Wash hands thoroughly af ter handling. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/f ace protection. P302+P352 IF ON SKIN Wash with soap and water. P305+P351+P338 IF IN EYES Rinse cautiously with water f or several minutes. Remove contact lenses if present and easy to do. continue rinsing. P332+P313 If skin irritation occurs Get medical advice/attention. P337+P313 If eye irritation persists Get medical advice/attention. P362 Take of f contaminated clothing and wash bef ore reuse. P391 Collect spillage. P501 Dispose of contents/container to an approved waste disposal plant. Hazards Not Otherwise Classified No data available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name TERBINAFINE HCL Common Name Terbinaf ine hydrochloride CAS Number 78628-80-5 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice Show this saf ety data sheet to the doctor in attendance. If Inhaled Remove to fresh air. Get medical attention immediately if symptoms occur. In Case of Skin Contact Wash of f immediately with soap and plenty of water f or at least 15 minutes. Get medical attention if irritation develops and persists. In Case of Eye Contact Rinse immediately with plenty of water, also under the eyelids, f or at least 15 minutes. Keep eye wide open while rinsing. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical attention if irritation develops and persists. Do not rub af f ected area. If Swallowed Clean mouth with water and drink af terwards plenty of water. Never give anything by mouth to an unconscious person. Do NOT induce vomiting. Call a doctor. Most Important Symptoms and Effects Burning sensation. Dizziness. Headache. Rashes. Nausea. Vomiting. Abdominal pain. Page 1 of 4 Section 5: Fire Fighting Measures Suitable Extinguishing Media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Special Hazards Arising From the Substance/Mixture Not f lammable Explosive properties: Not an explosive. Dust can f orm an explosive mixture with air. Hazardous combustion products: Carbon oxides. Hydrocarbons. Hydrogen cyanide. Special PPE and/or Precautions for Firefighters Firef ighters should wear self-contained breathing apparatus and f ull f iref ighting turnout gear. Use personal protection equipment. Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Avoid contact with skin, eyes or clothing. Ensure adequate ventilation. Use personal protective equipment as required. Methods and Materials Used for Containment Prevent f urther leakage or spillage if saf e to do so. Cleanup Procedures Use appropriate personal protective equipment (PPE). Caref ully shovel or sweep up spilled material and place in suitable container. Avoid generating dust. For spills:. Soak up with inert absorbent material. Use clean non-sparking tools to collect material and place it into loosely covered plastic containers f or later disposal. Avoid breathing dust or spray mist. Section 7: Handling and Storage Precautions for Safe Handling Handle in accordance with good industrial hygiene and saf ety practice. Avoid contact with skin, eyes or clothing. Do not eat, drink or smoke when using this product. Take of f contaminated clothing and wash it bef ore reuse. General hygiene considerations: Wear suitable gloves and eye/f ace protection. Do not eat, drink or smoke when using this product. Avoid contact with skin, eyes or clothing. Conditions for Safe Storage Keep containers tightly closed in a dry, cool and well-ventilated place. Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters No inf ormation available Appropriate Engineering Controls Apply technical measures to comply with the occupational exposure limits. Ensure adequate ventilation, especially in conf ined areas. Ensure that eyewash stations and saf ety showers are close to the workstation location. PPE - Eye/Face Protection If splashes are likely to occur, wear saf ety glasses with side-shields. PPE - Skin Protection Wear suitable protective clothing. Long sleeved clothing.Wear suitable gloves. Impervious gloves. PPE - Body Protection Wear suitable protective clothing. Long sleeved clothing.Wear suitable gloves. Impervious gloves.If splashes are likely to occur, wear saf ety glasses with side-shields. PPE - Respiratory Protection Use appropriate respiratory protection. Section 9: Physical and Chemical Properties Appearance crystalline powder White to of f-white Upper/Lower Flammability or Explosive Limits No data available Odor No data available Vapor Pressure No data available Odor Threshold No data available Vapor Density No data available pH No data available Relative Density No data available Melting Point/Freezing Point No data available Solubility Slightly soluble in water. Soluble in Methanol Initial Boiling Point and Boiling Range No data available Flash Point No data available Evaporation Rate No data available Flammability (Solid, Gas) No data available Partition Coefficient No data available Auto-Ignition Temperature No data available Decomposition Temperature No data available Viscosity No data available Page 2 of 4 Section 10: Stability and Reactivity Reactivity Stable under normal conditions. Chemical Stability Stable under normal conditions. Possibility of Hazardous Reactions None under normal processing. Conditions to Avoid Extremes of temperature and direct sunlight Incompatible Materials Strong acids. Strong bases. Strong oxidising agents. Hazardous Decomposition Products None under normal use conditions. Section 11: Toxicological Information Acute Toxicity - LD50 Oral > 4000 mg/k(Rat ) Acute Toxicity - Inhalation May cause irritation of respiratory tract. Acute Toxicity - Dermal No data available Acute Toxicity - Eye Classif ication based on data available f or ingredients. Irritating to eyes. Skin Corrosion/Irritation Classif ication based on data available f or ingredients. Irritating to skin. Serious Eye Damage/Irritation Classif ication based on data available f or ingredients. Irritating to eyes. Respiratory or Skin Sensitazation Based on available data, the classif ication criteria are not met. Germ Cell Mutagenicity Based on available data, the classif ication criteria are not met. Carcinogenicity IARC No data available Carcinogenicity ACGIH No data available Carcinogenicity NTP No data available Carcinogenicity OSHA Based on available data, the classif ication criteria are not met. Reproductive Toxicity Based on available data, the classif ication criteria are not met. Specific Target Organ Toxicity - Single Exposure Based on available data, the classif ication criteria are not met. Specific Target Organ Toxicity - Repeated Exposure Based on available data, the classif ication criteria are not met. Aspiration Hazard Based on available data, the classif ication criteria are not met. Section 12: Ecological Information Toxicity Very toxic to aquatic lif e with long lasting ef f ects.Algae/aquatic plants EC50 (Green Algae ): 0.029 mg/L,72h (growth rate) Persistence and Degradability No data available Bio-accumulative Potential No data available Mobility in Soil No data available Other Adverse Effects No data available Section 13: Disposal Considerations Waste Treatment Methods Product Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation. Should not be released into the environment. Waste Treatment Methods Packaging Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation. Should not be released into the environment. Special Precautions Landfill or Incinerations Dispose of in accordance with local regulations. Dispose of waste in accordance with environmental legislation. Should not be released into the environment. Other Information No data available Section 14: Transport Information UN Number UN 3077 UN Proper Shipping Name Terbinaf ine Hydrochloride Transport Hazard Class(es) Hazard Class: 9 Packaging Group III Environmental Hazards Yes Page 3 of 4 Section 15: Regulatory Information N/A Section 16: Other Information Additional Information N/A Prepared By Lisa Russell Revision Date 01/09/2019 16:21 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
