MICONAZOLE NITRATE, USP 100GM by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name MICONAZOLE NITRATE USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) 1H-imidazole, 1-[2-(2,4-dichlorophenyl)-methoxy] ethyl,monoitrate Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Acute toxicity, Oral (Category 4), Hazardous to the aquatic environment - Acute hazard (Category 1), Hazardous to the aquatic environment - Chronic hazard (Category 1) Signal Word Warning Hazard Statement(s) H302 Harmf ul if swallowed H410 Very toxic to aquatic lif e with long lasting ef f ects Pictogram(s) Precautionary Statement(s) P264 Wash hands thoroughly af ter handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P301+P312 IF SWALLOWED Call a POISON CENTER or doctor/physician if you f eel unwell. P330 Rinse mouth. P391 Collect spillage. P501 Dispose of contents/container to an approved waste disposal plant. Hazards Not Otherwise Classified No data available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name 1H-imidazole, 1-[2-(2,4-dichlorophenyl)-methoxy] ethyl,monoitrate Common Name Miconazole Nitrate CAS Number 22832-87-7 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice If you f eel unwell, seek medical advice (show the label where possible. Never give anything by mouth to an unconscious person. If Inhaled Assure fresh air breathing. Allow the victim to rest. In Case of Skin Contact Remove af f ected clothing and wash all exposed skin area with mild soap and water, f ollowed by warm water rinse. In Case of Eye Contact Rinse immediately with plenty of water. Obtain medical attention if pain, blinking or redness persist. If Swallowed Rinse mouth immediately call a POISON CENTER or doctor. Specif ic treatment. Obtain emergency medical attention. Most Important Symptoms and Effects Symptoms relating to use: Swallowing a small quantity of this material will result in serious health hazard. Section 5: Fire Fighting Measures Suitable Extinguishing Media Water spray, Foam, Dry powder, Carbon dioxide. Sand. Unsuitable extinguishing media: Do not use a heavy water stream. Surrounding f ires: Use water spray or f og f or cooling exposed containers. Special Hazards Arising From the Substance/Mixture Under f ire conditions, hazardous f umes will be present. Special PPE and/or Precautions for Firefighters Do not enter f ire area without proper protective equipment, including respiratory protection. Exercise caution when f ighting any chemical f ire . Avoid (reject) f ire-f ighting water to enter environment. Page 1 of 4 Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Ventilate area. Equip cleanup crew with proper protection. Evacuate unnecessary personnel. Methods and Materials Used for Containment On land, sweep up and shovel into suitable containers. Minimize generation of dust. Cleanup Procedures On land, sweep up and shovel into suitable containers. Minimize generation of dust. Avoid release to the environment. Prevent entry to sewers and public water. Notif y authorities if product enter sewers or public waters. Section 7: Handling and Storage Precautions for Safe Handling Provide good ventilation in process area to prevent f ormation of vapour. Wash thoroughly af ter handling. Do not eat or drink or smoke when using this product. Conditions for Safe Storage Keep only in the original container in a cool, well ventilated place. Keep in container closed when no in use. Storage away from: Strong bases, Strong acids. Sources of ignition. Direct sunlight. Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters No data available Appropriate Engineering Controls Avoid all unnecessary exposure. PPE - Eye/Face Protection Chemical goggles or saf ety glasses. PPE - Skin Protection Wear protective gloves. In case or repeated or prolonged contact wear gloves. PPE - Body Protection Wear protective gloves. In case or repeated or prolonged contact wear gloves. PPE - Respiratory Protection Where excessive vapour may result, wear approved mask. Section 9: Physical and Chemical Properties Appearance Form: Powder Colour: White Upper/Lower Flammability or Explosive Limits No data available Odor Odourless Vapor Pressure No data available Odor Threshold No data available Vapor Density No data available pH 4 Relative Density No data available Melting Point/Freezing Point 184 �C Solubility Soluble if mixed with: Acetone (1,80 g/l) Initial Boiling Point and Boiling Range No data available Flash Point No data available Evaporation Rate No data available Flammability (Solid, Gas) No data available Partition Coefficient Log Pow octanol/water 20 �C 5.79 Auto-Ignition Temperature Auto-ignition temperature �C Not applicable 350 Decomposition Temperature No data available Viscosity No data available Section 10: Stability and Reactivity Reactivity Not established Chemical Stability Stable under recommended storage conditions. Possibility of Hazardous Reactions Not established Conditions to Avoid Extremely high or low temperatures. Direct sunlight. Incompatible Materials Strong bases, Strong acids Hazardous Decomposition Products Fume. Carbon moNOxide. Carbon dioxide. Page 2 of 4 Section 11: Toxicological Information Acute Toxicity - LD50 Oral Rat oral LD50 [mg/kg/24h] >640 (920 mg/kg) Dog Oral LD50 [mg/kg] >160 Oral DL (pig) [mg/kg] 275.9 Acute Toxicity - Inhalation No data available Acute Toxicity - Dermal No data available Acute Toxicity - Eye No data available Skin Corrosion/Irritation No data available Serious Eye Damage/Irritation No data available Respiratory or Skin Sensitazation May cause an allergic skin reaction. Germ Cell Mutagenicity Not mutagenic in Ames test with Salmonella typhimurium and Escherichia coli, and in Klebsiella pneumonia. Carcinogenicity IARC No data available Carcinogenicity ACGIH No data available Carcinogenicity NTP No data available Carcinogenicity OSHA No data available Reproductive Toxicity No data available Specific Target Organ Toxicity - Single Exposure No data available Specific Target Organ Toxicity - Repeated Exposure No data available Aspiration Hazard No data available Section 12: Ecological Information Toxicity Very toxic to aquatic lif e with long lasting ef f ects. 48 hour-EC50-Daphnia magna [mg/l] : No data available. LC50 96 Hour-f ish [mg/l] 0.144. Persistence and Degradability Biodegradable Bio-accumulative Potential No data available Mobility in Soil LopP (5,79) Log Pow Octanol/water at 20 �?°C No data available Other Adverse Effects Avoid release to the environment. Section 13: Disposal Considerations Waste Treatment Methods Product Dispose of this material and its container to hazardous or special waste collection point, in accordance with local, regional, national, and or international regulation. Dispose in saf e manner in accordance with local/national regulations. Avoid release to the environment. Waste Treatment Methods Packaging Avoid release to the environment. Hazardous waste due to toxicity. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number UN Proper Shipping Name Transport Hazard Class(es) Packaging Group Environmental Hazards Marine Pollutant: No Poison Inhalation Hazard: No Section 15: Regulatory Information Saf ety, health and environmental regulations/legislation specif ic f or the substance or mixture. Ensure all national/local regulations are observed. Chemical Saf ety Assessment: It has not been carried out. Section 16: Other Information Additional Information N/A Prepared By Lisa Russell Revision Date 01/11/2019 09:14 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is Page 3 of 4 based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
