Temaril-P Tabs-Trimeprazine with Prednisolone
Recommended for the relief of itching and inflammation commonly associated with most skin disorders of dogs such as the eczema. It has been found to be effective therapy and adjunctive therapy in various cough conditions of dogs such as "kennel cough" or tracheobronchitis, bronchitis including all allergic bronchitis and infections and coughs of nonspecific origin. Each tablet contains trimeprazine tartrate USP equivalent to trimeprazine, 5 mg, and prednisolone, 2 mg.
Temaril-P Tabs
Recommended for the relief of itching and inflammation commonly associated with most skin disorders of dogs such as the eczema. It has been found to be effective therapy and adjunctive therapy in various cough conditions of dogs such as "kennel cough" or tracheobronchitis, bronchitis including all allergic bronchitis and infections and coughs of nonspecific origin. Each tablet contains trimeprazine tartrate USP equivalent to trimeprazine, 5 mg, and prednisolone, 2 mg.
WARNING: Clinical and experimental data have demonstrated that corticosteroids administered orally or by injection to animals may induce the first stage of parturition if used during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Additionally, corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring. Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia, and anasarca. If a vasoconstrictor is needed, norepinephrine should be used in lieu of epinephrine. Phenothiazine derivatives may reverse the usual elevating action of epinephrine causing a further lowering of blood pressure.
PRECAUTIONS AND SIDE EFFECTS: All the precautions applicable to cortisone and to phenothiazine derivatives apply also to Temaril-P. Possible side effects attributable to corticosteroids include sodium retention and potassium loss, negative nitrogen balance, suppressed adrenal cortical function, delayed wound healing, osteoporosis, elevated levels of SGPT and SAP, and vomiting and diarrhea (occasionally bloody). Cushings syndrome in dogs has been reported in association with prolonged or repeated steroid therapy. Possible increased susceptibility to bacterial invasion and/or the exacerbation of preexisting bacterial infection may occur in patients receiving corticosteroids. As noted above, however, this problem can be avoided by concomitant use of appropriate anti-infective agents. Possible side effects attributable to phenothiazine derivatives include sedation; protruding nictitating membrane; blood dyscrasias; intensification and prolongation of the action of analgesics, sedatives and general anesthetics; and potentiation of organophosphate toxicity and the activity of procaine hydrochloride.
