Medrol Tabs 4mg
Methylprednisolone, a potent synthetic anti-inflammatory steroid. Improves anti-inflammatory action by 25%, with even less tendency to induce sodium and water retention. With its enhanced potency, lower doses achieve results similar to prednisone and prednisolone, but reduce the risk of side effects. For oral use in dogs and cats.
INDICATIONS
� Dermal conditions, such as non-specific eczema, summer dermatitis and burns
� Allergic manifestations, such as acute urticaria, allergic dermatitis, drug and serum reactions, bronchial asthma, and pollen sensitivities
� Ocular conditions, such as iritis, iridocyclitis, secondary glaucoma, uveitis and chorioretinitis
� Otic conditions, such as otitis externa
� Musculoskeletal conditions, such as myositis, rheumatoid arthritis, osteoarthritis, and bursitis
� Various chronic or recurrent diseases of unknown etiology, such as ulcerative colitis and nephrosis
MEDROL�
Zoetis
NDC 0009-3547-01
brand of methylprednisolone tablets
For Oral Use in Dogs and Cats
NADA No. 011-403, Approved by FDA
Methylprednisolone, a potent anti-inflammatory steroid synthesized and developed in the Research Laboratories of The Upjohn Company is the 6-methyl derivative of prednisolone. It has a greater anti-inflammatory potency than prednisolone and even less tendency than prednisolone to induce sodium and water retention. Its advantage over the older corticoids lies in its ability to achieve equal anti-inflammatory effect with lower dose, while at the same time enhancing the split between anti-inflammatory and mineralocorticoid activities.
INDICATIONS
The indications for MEDROL Tablets are the same as those for other anti-inflammatory steroids and comprise the various collagen, dermal, allergic, ocular, otic, and musculoskeletal conditions known to be responsive to the anti-inflammatory corticosteroids. Representative of the conditions in which the use of steroid therapy and the benefits to be derived therefrom have had repeated confirmation in the veterinary literature are: (1) dermal conditions, such as non-specific eczema, summer dermatitis, and burns; (2) allergic manifestations, such as acute urticaria, allergic dermatitis, drug and serum reactions, bronchial asthma, and pollen sensitivities; (3) ocular conditions, such as iritis, iridocyclitis, secondary glaucoma, uveitis, and chorioretinitis; (4) otic conditions, such as otitis externa; (5) musculoskeletal conditions, such as myositis, rheumatoid arthritis, osteoarthritis, and bursitis; (6) various chronic or recurrent diseases of unknown etiology such as ulcerative colitis and nephrosis.
In acute adrenal insufficiency, MEDROL may be effective because of its ability to correct the defect in carbohydrate metabolism and relieve the impaired diuretic response to water characteristic of primary or secondary adrenal insufficiency. However, because this agent lacks significant mineralocorticoid activity, the parent hormones, SOLU-CORTEF� containing hydrocortisone sodium succinate, CORTEF� containing hydrocortisone, or cortisone should be used when salt retention is indicated.
CONTRAINDICATIONS
MEDROL Tablets like prednisolone, are contraindicated in animals with arrested tuberculosis, peptic ulcer, acute psychoses, and Cushingoid syndrome. The presence of diabetes, osteoporosis, chronic psychotic reactions, predisposition to thrombophlebitis, hypertension, congestive heart failure, renal insufficiency, and active tuberculosis necessitates carefully controlled use. Some of the above conditions occur only rarely in dogs and cats but should be kept in mind.
Warning: Not for human use. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis.
DOSAGE
Average total daily oral doses for dogs and cats are as follows:
5 to 15 lb body wt
2 mg
15 to 40 lb body wt
2 to 4 mg
40 to 80 lb body wt
4 to 8 mg
The total daily dose should be given in divided doses, 6 to 10 hours apart.
HOW SUPPLIED
Veterinary MEDROL Tablets are compressed cross-scored tablets available in the following strength:
Bottles of 500
NDC 0009-3547-01
