Zoetis
(doramectin)
Pour-On
Antiparasitic
0.5% pour-on solution for cattle
5 mg/mL
PRODUCT DESCRIPTION: Dectomax Pour-On solution is a ready-to-use, systemically active, clear, light blue solution containing 0.5% w/v doramectin (5 mg/mL). It is formulated to deliver the recommended dosage of 500 mcg/kg (227 mcg/lb) of body weight when given by topical administration at the rate of 1 mL/22 lb (10 kg) of body weight.
PRODUCT CHARACTERISTICS: Dectomax Pour-On solution is a highly active, broad-spectrum parasiticide for topical administration to cattle. It contains doramectin, a novel fermentation-derived macrocyclic lactone. Doramectin is isolated from fermentations of selected strains derived from the soil organism Streptomyces avermitilis.
A primary mode of action of macrocyclic lactones is to modulate chloride ion channel activity in the nervous system of nematodes and arthropods. Macrocyclic lactones bind to receptors that increase membrane permeability to chloride ions. This inhibits the electrical activity of nerve cells in nematodes and muscle cells in arthropods and causes paralysis and death of the parasites. In mammals, the neuronal receptors to which macrocyclic lactones bind are localized within the central nervous system (CNS), a site reached by only negligible concentrations of doramectin.
One dose of Dectomax Pour-On solution effectively treats and controls a wide range of roundworm and arthropod parasites that impair the health and productivity of cattle.
PRODUCT INDICATIONS: Dectomax Pour-On solution is indicated for the treatment and control of the following species of gastrointestinal roundworms, lungworms, eyeworms, grubs (see PRECAUTIONS), biting and sucking lice, horn flies, and mange mites in cattle. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Gastrointestinal roundworms
Ostertagia ostertagi (adults and L4, including inhibited larvae)
O. lyrata (adults)
Haemonchus placei (adults and L4)
Trichostrongylus axei (adults and L4)
T. colubriformis (adults and L4)
Cooperia oncophora (adults1 and L4)
C. pectinata (adults)
C. punctata (adults and L4)
C. surnabada (adults)
Bunostomum phlebotomum (adults)
Oesophagostomum radiatum (adults and L4)
Trichuris spp. (adults)
1 Efficacy below 90% was observed against adult C. oncophora in some clinical studies.
Lungworms (adults and fourth stage larvae)
Dictyocaulus viviparus
Eyeworms
Thelazia gulosa (adults)
T. skrjabini (adults)
Lice
Biting Lice
Bovicola (Damalinia) bovis
Sucking Lice
Haematopinus eurysternus
Linognathus vituli
Solenopotes capillatus
Grubs
Hypoderma bovis
H. lineatum
Horn Flies
Haematobia irritans
Mange Mites
Chorioptes bovis
Sarcoptes scabiei
Dectomax Pour-On solution has been proved to effectively control infections and to protect cattle from reinfection with Cooperia oncophora, Dictyocaulus viviparus, Ostertagia ostertagi, and Oesophagostomum radiatum for 28 days; and Cooperia punctata and Haemonchus placei for 35 days after treatment.
Dectomax Pour-On solution has been proved to effectively control infestations and to protect cattle from reinfestation with Bovicola (Damalinia) bovis for 77 days and Linognathus vituli for 42 days after treatment.
Applicators (2.5-L and 5-L bottles)
Applicators are available for use with Dectomax Pour-On solution supplied in 2.5- and 5-L backpacks. Directions for 2 recommended applicators are provided below. Some applicators may be incompatible with this formulation.
Phillips Pour-on Applicator System
1. Replace the shipping cap on 2.5- or 5-L backpack with the draw-off cap provided and tighten firmly.
2. Thread the draw-off tubing through the anti-kink spring. Attach the tube to the draw-off cap. Screw the spring counter clockwise over the tubing and draw-off spigot.
3. Invert the backpack.
4. Set the dose to maximum (50 mL). Gently prime the applicator, checking for leaks. To prime, place the nozzle into a clean, dry receptacle and depress lever fully. Pump 3-4 short strokes ensuring that the piston reaches the end of the cylinder, and then release the lever completely to fill the cylinder. A small air bubble may appear within the cylinder. This will not affect the dosing accuracy.
5. Set the required dose and administer.
6. To disconnect the system, proceed as follows:
a) Set backpack in upward position.
b) Discharge residual material from the applicator and draw-off tubing into a separate, clean, dry receptacle.
7. Follow the manufacturer’s recommendation for care and maintenance of the dosing applicator.
8. Remove the draw-off cap. Replace with the original cap and tighten firmly.
Syrvet Pour-on Applicator System
1. Replace the shipping cap on the 2.5- or 5-L backpack with the draw-off cap provided and tighten firmly.
2. Thread the draw-off tubing through the anti-kink spring. Attach the tube to the draw-off cap. Screw the spring clockwise over the tubing and draw-off spigot.
3. Invert the backpack.
4. Set the dose at the maximum (50 mL) by unscrewing the adjuster at the base of the handle. Gently prime the applicator, checking for leaks. To prime, point the nozzle into a clean, dry receptacle and gently pump the lever back and forth to expel air from the system. When the barrel completely fills after every priming stroke, set the dose.
5. Set the dose as follows:
a) Use the handle to align the middle of the blue plunger ring with the chosen mark on the barrel. Tighten the adjuster screw against the handle.
b) Secure the dose with the adjuster screw locknut.
WARNING: Flammable! Keep away from heat, sparks, open flame, and other sources of ignition. Not for human use. Keep out of reach of children. The Material Safety Data Sheet (MSDS) contains more detailed occupational safety information. To report adverse effects in users, to obtain more information, or to obtain an MSDS, call 1-888-963-8471.
PRECAUTIONS:
Dectomax Pour-On solution has been developed specifically for use in cattle only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.
This product is to be applied to skin surface only. Do not administer orally or parenterally.
Do not apply to areas of skin which are caked with mud or manure.
Wash hands after use.
Do not smoke or eat while handling the product.
Cloudiness in the formulation may occur when Dectomax Pour-On solution is stored at temperatures below 0°C (32°F). Allowing to warm to room temperature will restore the normal appearance without affecting efficacy.
Dectomax Pour-On solution is highly effective against cattle grubs. However, proper timing of treatment is important. For most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble) season.
USE CONDITIONS: Varying weather conditions, including rainfall, do not affect the efficacy of Dectomax Pour-On.
ENVIRONMENTAL SAFETY: Studies indicate that when doramectin comes in contact with the soil, it readily and tightly binds to the soil and becomes inactive over time. Free doramectin may adversely affect fish and certain aquatic organisms. Do not permit cattle to enter lakes, streams or ponds for at least 6 hours after treatment. Do not contaminate water by direct application or by the improper disposal of drug containers. Dispose of containers in an approved landfill or by incineration. As with other avermectins, doramectin is excreted in the dung of treated animals and can inhibit the reproduction and growth of pest and beneficial insects that use dung as a source of food and for reproduction. The magnitude and duration of such effects are species and life-cycle specific. When used according to label directions, the product is not expected to have an adverse impact on populations of dung-dependent insects.
Store Below 30°C (86°F)
Protect From Light
HOW SUPPLIED: Dectomax Pour-On solution is available in 250-mL, 1-L, 2.5-L, and 5-L multi-dose containers.
NADA #141-095, Approved by FDA
Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Not for human use
