Dectomax Pour On
Doramectin (5 mg/mL), a highly active, broad-spectrum parasiticide for topical administration to cattle.
DECTOMAX�
Zoetis
(doramectin)
Pour-On
Antiparasitic
0.5% pour-on solution for cattle
5 mg/mL
PRODUCT DESCRIPTION: Dectomax Pour-On solution is a ready-to-use, systemically active, clear, light blue solution containing 0.5% w/v doramectin (5 mg/mL). It is formulated to deliver the recommended dosage of 500 mcg/kg (227 mcg/lb) of body weight when given by topical administration at the rate of 1 mL/22 lb (10 kg) of body weight.
PRODUCT CHARACTERISTICS: Dectomax Pour-On solution is a highly active, broad-spectrum parasiticide for topical administration to cattle. It contains doramectin, a novel fermentation-derived macrocyclic lactone. Doramectin is isolated from fermentations of selected strains derived from the soil organism Streptomyces avermitilis.
A primary mode of action of macrocyclic lactones is to modulate chloride ion channel activity in the nervous system of nematodes and arthropods. Macrocyclic lactones bind to receptors that increase membrane permeability to chloride ions. This inhibits the electrical activity of nerve cells in nematodes and muscle cells in arthropods and causes paralysis and death of the parasites. In mammals, the neuronal receptors to which macrocyclic lactones bind are localized within the central nervous system (CNS), a site reached by only negligible concentrations of doramectin.
One dose of Dectomax Pour-On solution effectively treats and controls a wide range of roundworm and arthropod parasites that impair the health and productivity of cattle.
PRODUCT INDICATIONS: Dectomax Pour-On solution is indicated for the treatment and control of the following species of gastrointestinal roundworms, lungworms, eyeworms, grubs (see PRECAUTIONS), biting and sucking lice, horn flies, and mange mites in cattle. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Gastrointestinal roundworms
Ostertagia ostertagi (adults and L4, including inhibited larvae)
O. lyrata (adults)
Haemonchus placei (adults and L4)
Trichostrongylus axei (adults and L4)
T. colubriformis (adults and L4)
Cooperia oncophora (adults1 and L4)
C. pectinata (adults)
C. punctata (adults and L4)
C. surnabada (adults)
Bunostomum phlebotomum (adults)
Oesophagostomum radiatum (adults and L4)
Trichuris spp. (adults)
1 Efficacy below 90% was observed against adult C. oncophora in some clinical studies.
Lungworms (adults and fourth stage larvae)
Dictyocaulus viviparus
Eyeworms
Thelazia gulosa (adults)
T. skrjabini (adults)
Lice
Biting Lice
Bovicola (Damalinia) bovis
Sucking Lice
Haematopinus eurysternus
Linognathus vituli
Solenopotes capillatus
Grubs
Hypoderma bovis
H. lineatum
Horn Flies
Haematobia irritans
Mange Mites
Chorioptes bovis
Sarcoptes scabiei
Dectomax Pour-On solution has been proved to effectively control infections and to protect cattle from reinfection with Cooperia oncophora, Dictyocaulus viviparus, Ostertagia ostertagi, and Oesophagostomum radiatum for 28 days; and Cooperia punctata and Haemonchus placei for 35 days after treatment.
DOSAGE: Administer Dectomax Pour-On solution to cattle topically at a dosage of 500 mcg doramectin per kg (227 mcg/lb) of body weight. Each mL contains 5 mg of doramectin, sufficient to treat 22 lb (10 kg) of body weight.
For the best results, Dectomax Pour-On solution should be a part of a parasite control program for both internal and external parasites based on the epidemiology of these parasites. Consult a veterinarian or an entomologist for information regarding the most effective timing of applications.
Phillips Pour-on Applicator System
1. Replace the shipping cap on 2.5- or 5-L backpack with the draw-off cap provided and tighten firmly.
2. Thread the draw-off tubing through the anti-kink spring. Attach the tube to the draw-off cap. Screw the spring counter clockwise over the tubing and draw-off spigot.
3. Invert the backpack.
4. Set the dose to maximum (50 mL). Gently prime the applicator, checking for leaks. To prime, place the nozzle into a clean, dry receptacle and depress lever fully. Pump 3-4 short strokes ensuring that the piston reaches the end of the cylinder, and then release the lever completely to fill the cylinder. A small air bubble may appear within the cylinder. This will not affect the dosing accuracy.
5. Set the required dose and administer.
6. To disconnect the system, proceed as follows:
a) Set backpack in upward position.
b) Discharge residual material from the applicator and draw-off tubing into a separate, clean, dry receptacle.
7. Follow the manufacturer's recommendation for care and maintenance of the dosing applicator.
8. Remove the draw-off cap. Replace with the original cap and tighten firmly.
Syrvet Pour-on Applicator System
1. Replace the shipping cap on the 2.5- or 5-L backpack with the draw-off cap provided and tighten firmly.
2. Thread the draw-off tubing through the anti-kink spring. Attach the tube to the draw-off cap. Screw the spring clockwise over the tubing and draw-off spigot.
3. Invert the backpack.
4. Set the dose at the maximum (50 mL) by unscrewing the adjuster at the base of the handle. Gently prime the applicator, checking for leaks. To prime, point the nozzle into a clean, dry receptacle and gently pump the lever back and forth to expel air from the system. When the barrel completely fills after every priming stroke, set the dose.
5. Set the dose as follows:
a) Use the handle to align the middle of the blue plunger ring with the chosen mark on the barrel. Tighten the adjuster screw against the handle.
b) Secure the dose with the adjuster screw locknut.
USE CONDITIONS: Varying weather conditions, including rainfall, do not affect the efficacy of Dectomax Pour-On.
Store Below 30�C (86�F)
Protect From Light
HOW SUPPLIED: Dectomax Pour-On solution is available in 250-mL, 1-L, 2.5-L, and 5-L multi-dose containers.
NADA #141-095, Approved by FDA
Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
Not for human use
