Cestex Tabs (Brown) 25mg
Cestex (epsiprantel) tablets are indicated for the removal of tapeworms in cats (Dipylidium caninum and Taenia taeniaeformis) and dogs (Dipylidium caninum and Taenia pisiformis). Only one dose is needed. Fasting is not necessary or recommended. Do not use in animals younger than 7 weeks.
Cestex®
Zoetis
(epsiprantel)
Veterinary Tablets
Cestex (epsiprantel) tablets are indicated for the removal of tapeworms in the cat (Dipylidium caninum and Taenia taeniaeformis) and dog (Dipylidium caninum and Taenia pisiformis).
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
DESCRIPTION: Cestex tablets are film-coated and contain 12.5 mg, 25 mg, 50 mg or 100 mg of epsiprantel per tablet.
Epsiprantel is an anthelmintic that is active as a single dose against the common tapeworms of cats and dogs. Epsiprantel has a molecular weight of 326 and is chemically 2-(cyclohexylcarbonyl)-4-oxo 1,2,3,4,6,7,8,12b-octahydropyrazino[2,1-a][2]benza-zepine. It is a stable white solid which is sparingly soluble in water. Its chemical structure is presented below.
Action: Epsiprantel acts directly on the tapeworm. Since it is minimally absorbed following oral administration, epsiprantel remains at the site of action within the gastrointestinal tract. Due to digestive process, tapeworm fragments or proglottids may not be readily visible in the stool.
INDICATIONS AND USAGE: Cestex tablets are indicated for the removal of the following:
Feline cestodes: Dipylidium caninum and Taenia taeniaeformis
Canine cestodes: Dipylidium caninum and Taenia pisiformis
CONTRAINDICATIONS: There are no known contraindications to the use of this drug.
WARNINGS: For use in cats and dogs only. Safety of use in pregnant or breeding animals has not been determined. Keep out of reach of children. Not for use in humans.
PRECAUTION: Do not use in kittens or puppies less than 7 weeks of age.
DOSAGE AND ADMINISTRATION: Cestex tablets should be administered orally.
The recommended dosage of epsiprantel is: cats, 1.25 mg/lb of body weight; dogs, 2.5 mg/lb of body weight. The following table may be used as a guide:
Dosage Schedule
Feline
|
Body Weight
|
Dose
|
|
Seven weeks old
|
|
up to 10 lb
|
12.5 mg
|
|
11-20 lb
|
25.0 mg
|
Canine
|
Body Weight
|
Dose
|
|
Seven weeks old
|
|
up to 5 lb
|
12.5 mg
|
|
6-10 lb
|
25.0 mg
|
|
11-20 lb
|
50.0 mg
|
|
21-40 lb
|
100.0 mg
|
|
41-50 lb
|
125.0 mg
|
|
51-60 lb
|
150.0 mg
|
|
61-80 lb
|
200.0 mg
|
|
81-90 lb
|
225.0 mg
|
|
91-100 lb
|
250.0 mg
|
|
101+ lb
|
2.5 mg/lb, rounding up to next whole tablet combination
|
Fasting is not necessary or recommended.
Unless exposure to the infected intermediate hosts is controlled, reinfection is likely and retreatment may be required. In the case of D. caninum, an effective flea control program should be instituted.
STORAGE: Store at controlled room temperature 20°-25°C (68°-77°F) with excursions between 15°-30°C (59°-86°F).
HOW SUPPLIED: Cestex tablets are film-coated and contain 12.5 mg, 25 mg, 50 mg or 100 mg of epsiprantel per tablet. Cestex is supplied as described below:
|
Concentration
|
Weight (lbs)
|
Number Tablets/Bottle
|
|
Cat
|
Dog
|
|
12.5 mg
|
10
|
5
|
50, 100
|
|
25.0 mg
|
20
|
10
|
50, 100
|
|
50.0 mg
|
- -
|
20
|
25, 50
|
|
100.0 mg
|
- -
|
40
|
25, 50
|
