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RX ITEM-Sivextro 200Mg Vial 10 By Merck

NDC 67919-0040-01 UPC/GTIN No.3-67919-04001-6 Mfg.Part No.4001BRAND: SIVEXTRO NDC: 67919-0040-01,67919004001 UPC: 3-67919-04001-6,367919040016 Merck & Co.Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Sivextro 200Mg Vial 10 By Merck

$3692.88$3298.38

item No.:RX459040 NDC No.67919004001 UPC No.:367919040016 NDC No. 67919-0040-01 UPC/GTIN No. 3-67919-04001-6 MPN 4001 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No. Rx459040 Sivextro 200mg Vial 10 by Merck Item No. 3459040 NDC No. 67919004001 UPC No. 367919040016 Other Name Sivextro, tedizolid T

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SIVEXTRO- tedizolid phosphate tablet, film coated
SIVEXTRO- tedizolid phosphate injection, powder, lyophilized, for solution
Merck Sharp & Dohme Corp.
1 INDICATIONS AND USAGE
1.1 Acute Bacterial Skin and Skin Structure Infections

SIVEXTRO� is an oxazolidinone-class antibacterial indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible isolates of the following Gram-positive microorganisms: Staphylococcus aureus (including methicillin-resistant [MRSA] and methicillin-susceptible [MSSA] isolates), Streptococcus pyogenes , Streptococcus agalactiae , Streptococcus anginosus Group (including Streptococcus anginosus , Streptococcus intermedius , and Streptococcus constellatus), and Enterococcus faecalis.
1.2 Usage

To reduce the development of drug-resistant bacteria and maintain the effectiveness of SIVEXTRO and other antibacterial drugs, SIVEXTRO should be used only to treat ABSSSI that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
2 DOSAGE AND ADMINISTRATION
2.1 Recommended Dosage

The recommended dosage of SIVEXTRO is 200 mg administered once daily for six (6) days either orally (with or without food) or as an intravenous (IV) infusion in patients 18 years of age or older.
DOSAGE FORMS AND STRENGTHS

SIVEXTRO 200 mg tablet is a yellow film-coated oval tablet; each tablet is debossed with "TZD" on one side and "200? on the other side.

SIVEXTRO for injection is a sterile, white to off-white lyophilized powder for injection in single-use vials of 200 mg. Each 200 mg vial must be reconstituted with Sterile Water for Injection and subsequently diluted only with 0.9% Sodium Chloride Injection, USP.
DESCRIPTION

SIVEXTRO (tedizolid phosphate), a phosphate prodrug, is converted to tedizolid in the presence of phosphatases.

Tedizolid phosphate has the chemical name [(5R)-(3-{3-Fluoro-4-[6-(2-methyl-2H -tetrazol- 5-yl) pyridin-3-yl]phenyl}-2-oxooxazolidin- 5-yl]methyl hydrogen phosphate.

Its empirical formula is C17 H16 FN6 O6 P and its molecular weight is 450.32.
CLINICAL PHARMACOLOGY
12.1 Mechanism of Action

Tedizolid phosphate is the prodrug of tedizolid, an antibacterial agent.

NDC 67919-0040-01 UPC/GTIN No.3-67919-04001-6 Mfg.Part No.4001
RX ITEM-Sivextro 200Mg Vial 10 By Merck
NDC 67919-0040-01 UPC/GTIN No.3-67919-04001-6 Mfg.Part No.4001

BRAND: SIVEXTRO NDC: 67919-0040-01,67919004001 UPC: 3-67919-04001-6,367919040016 Merck & Co.
Sivextro 200Mg Vial 10 By Merck
BRAND: SIVEXTRO NDC: 67919-0040-01,67919004001 UPC: 3-67919-04001-6,367919040016 Merck & Co.

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
TEDIZOLID PHOSPHATE INTRA
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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