Clinical Information
Gen. Code and Des.
1400 magnesium chloride INJECTION VIAL 200 MG/ML
GCN and Des.
4050 magnesium chloride INJECTION VIAL 200 MG/ML
Strength
200MG/ML
Dose Form
VIAL (ML)
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family
AHFS Class
28129200 ANTICONVULSANTS, MISCELLANEOUS
Active Ingredients
786 magnesium chloride 7791186
Inactive Ingredients
3192 benzyl alcohol 100516
MAGNESIUM CHLORIDE- magnesium chloride injection
Mylan Institutional LLC
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
Magnesium Chloride Injection is a sterile solution of Magnesium Chloride Hexahydrate in Water for Injection q.s. Each mL contains Magnesium Chloride Hexahydrate 200 mg, Sodium Chloride 9 mg, Benzyl Alcohol 1% as a preservative, Water for Injection, q.s. pH adjusted with Hydrochloric Acid and/or Sodium Hydroxide. Total osmolarity equivalent to 2.951 mOsm/mL.
Contains 1.97 mEq of Mg++ and Cl- per mL.
The structural formula is MgCl2 �6H2 O
ACTIONS
Magnesium is the second most plentiful cation within cellular fluids. It is an important activator of many enzyme systems and deficits are accompanied by a variety of functional disturbances.
INDICATIONS
As an electrolyte replenisher in magnesium deficiencies.
CONTRAINDICATIONS
Magnesium Chloride Injection should not be administered if there is renal impairment, marked myocardial disease or to comatose patients.
WARNING
Do not use if a precipitate is present.
PRECAUTIONS
The usual precautions for parenteral administration should be observed. Administer with caution if flushing and sweating occurs. A preparation of a calcium salt should be readily available for intravenous injection to counteract potential serious signs of magnesium intoxication. As long as deep tendon reflexes are active it is probable that the patient will not develop respiratory paralysis. Respiration and blood pressure should be carefully observed during and after administration of Magnesium Chloride Injection.
Pregnancy
Teratogenic Effects
Pregnancy Category C
Animal reproduction studies have not been conducted with magnesium chloride. It is also not known whether magnesium chloride can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Magnesium Chloride should be given to a pregnant woman only if clearly needed.
ADVERSE REACTIONS
Flushing, sweating, sharply lowered blood pressure,hypothermia, stupor and ultimately respiratory depression.
DOSAGE AND ADMINISTRATION
For intravenous infusion: 4 grams in 250 mL of 5%Dextrose Injection, at a rate not exceeding 3 mL per minute. Serum magnesium levels should serve as a guide to continued dosage.
USUAL DOSAGE RANGE
1 to 40 grams daily.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.
HOW SUPPLIED
Magnesium Chloride Injection 200 mg/mL (20% w/v).
NDC 67457-134-50
50 mL Multiple-Dose Vial. Individually boxed.
Store at 20� to 25�C (68� to 77�F). [See USP Controlled
Room Temperature.]
Manufactured for:
Mylan Institutional LLC
Rockford, IL 61103
Manufactured by:
Mylan Institutional
Galway, Ireland
0546L104
REVISED FEBRUARY 2013
MI:MAGNIJ:R2
PRINCIPAL DISPLAY PANEL - 200 mg/mL
NDC 67457-134-50 50 mL
Magnesium
Chloride
Injection
200 mg/mL
(20% w/v)
2.951 mOsm/mL
For Intravenous Use After
Dilution
Rx only Multiple-Dose Vial
Manufactured for:
Mylan Institutional LLC
Rockford, IL 61103 U.S.A.
Manufactured by:
Mylan Institutional
Galway, Ireland
MI:134:1C:R2
Mylan.com
Each mL contains: Magnesium
Chloride Hexahydrate 200 mg,
Sodium Chloride 9 mg, Benzyl
Alcohol 1% as a preservative,
Water for Injection q.s. pH adjusted
with Hydrochloric Acid and/or
Sodium Hydroxide.
Total osmolarity equivalent to
2.951 mOsm/mL.
Contains 1.97 mEq of Mg++ and CI�
per mL.
WARNING: DO NOT USE IF A
PRECIPITATE IS PRESENT.
Store at 20� to 25�C (68� to 77�F).
[See USP Controlled Room
Temperature.]
