Rx Item-Chromic Chloride 4mcg/ml Vial 25X10ml By Hospira Worldwide

CHROMIC CHLORIDE - chromic chloride injection, solution
American Regent, Inc.

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Rx Only

STERILE, NONPYROGENIC, TRACE ELEMENT

ADDITIVE FOR IV USE AFTER DILUTION

(Chromium 4 mcg/mL)



PRESERVATIVE FREE

DESCRIPTION

Chromic Chloride Injection, USP is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN). Each mL contains Chromic Chloride Hexahydrate 20.5 mcg, Water for Injection q.s. pH adjusted with Hydrochloric Acid if necessary. It delivers elemental Chromium 4 mcg/mL. The 10 mL vial is a single dose preservative free vial. Discard any unused portion.

CLINICAL PHARMACOLOGY

Trivalent chromium is part of glucose tolerance factor, an activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function.

Providing chromium during TPN prevents development of the following deficiency symptoms: impaired glucose tolerance, ataxia, peripheral neuropathy and a confusional state similar to mild/moderate hepatic encephalopathy.

Chromic Chloride Indications and Usage

Chromic Chloride Injection, USP is indicated for use as a supplement to intravenous solutions given for Total Parenteral Nutrition (TPN). Administration helps to maintain plasma levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

CONTRAINDICATIONS

Chromic Chloride Injection, USP should not be given undiluted by direct injection into a peripheral vein because of the potential for infusion phlebitis and increased renal loss of chromium from a bolus injection.

WARNINGS

This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum.

Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration.

Rx Item-Chromic Chloride 4mcg/ml Vial 25
Item No.: RX162404 NDC No.409409301 UPC No.:304094093017 NDC No. 00409-4093-01 UPC/GTIN No. 3-04094-09301-7 MPN No. 409301 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.L

Chromic Chloride 4Mcg/Ml Vial 25X10Ml By
BRAND: CHROMIC-CHLORIDE NDC: 00409-4093-01,409409301 UPC: 3-04094-09301-7,304094093017 Hospira Worldwide Inc.

CHROMIC CHLORIDE INTRAVEN
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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