Active Ingredient
doxycycline hyclate
Description
Doxirobe Gel (doxycycline 8.5%) is indicated for the treatment and control of periodontal disease in dogs. Doxycycline is a semi-synthetic tetracycline derivative that has a wide range of antimicrobial activity against microorganisms, particularly Gram-negative anaerobic bacteria, involved in periodontal disease. Upon contact with the aqueous environment (gingival crevicular fluid) the polymer will coagulate, resulting in the formation of a solid, pliable delivery system within the treated periodontal pocket(s). Doxycycline is released into the gingival crevicular fluid for a local effect on the microorganisms. Do not use in dogs younger than 1 year because the use of tetracyclines during tooth development has been associated with permanent discoloration of the teeth. Do not use in pregnant bitches. The use of the product in breeding dogs has not been evaluated. Clients should be advised to suspend brushing treated teeth for approximately 2 weeks following treatment.
