Active Ingredient
cloprostenol sodium
Description
Estrumate (cloprostenol injection) is indicated for the following:
1. For unobserved or non-detected estrus in beef cows, lactating dairy cows, and replacement beef and dairy heifers
2. For treatment of pyometra or chronic endometritis in beef cows, lactating dairy cows, and replacement beef and dairy heifers
3. For treatment of mummified fetus in beef cows, lactating dairy cows, and replacement beef and dairy heifers
4. For treatment of luteal cysts in beef cows, lactating dairy cows, and replacement beef and dairy heifers
5. For abortion of beef cows, lactating dairy cows, and replacement beef and dairy heifers
6. For estrus synchronization in beef cows, lactating dairy cows, and replacement beef and dairy heifers
7. For use with Fertagyl® (gonadorelin) to synchronize estrous cycles to allow for fixed time artificial insemination (FTAI) in lactating dairy cows.
Estrumate causes functional and morphological regression of the corpus luteum (luteolysis) in cattle. In normal, non-pregnant cycling animals, this effect on the life span of the corpus luteum usually results in estrus 2 to 5 days after treatment. In animals with prolonged luteal function (pyometra, mummified fetus, and luteal cysts), the induced luteolysis usually results in resolution of the condition and return to cyclicity. Pregnant animals may abort depending on the stage of gestation. See package insert for complete product details.
