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Rx Item-Colistimethate 150Mg Vial By Xellia Pharma

Item No.:RX871165 871165  NDC No.70594-0023-01 70594-023-01 7059402301 70594002301  UPC No.:3-70594-02301-4 370594-023014 370594023014 MPN 002301 BRAND: COLISTIMETHATE NDC: 42023-0131-01,42023013101 UPC: 3-42023-13101-6,342023131016 JHP PharmaOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.Item No.:RX871165 871165  NDC No.70594-0023-01 70594-023-01 7059402301 70594002301  UPC No.:3-70594-02301-4 370594-023014 370594023014 MPN 002301 XELLIA PHARMA USA

Rx Item-Colistimethate 150Mg Vial By Xellia Pharma

$33.60$27.99

Item No.:RX871165 871165 NDC No.70594-0023-01 70594-023-01 7059402301 70594002301 UPC No.:3-70594-02301-4 370594-023014 370594023014 MPN 002301 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx194151 Colistimethate 150mg Vial by Xellia Pharma Coly-Mycin M

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COLISTIMETHATE - colistimethate sodium injection, powder, lyophilized, for solution
Fresenius Kabi USA, LLC

Rx only

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Colistimethate for Injection, USP and other antibacterial drugs, Colistimethate for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

FOR INTRAMUSCULAR AND INTRAVENOUS USE

DESCRIPTION



Colistimethate for Injection, USP is a sterile parenteral antibiotic product which, when reconstituted (see Reconstitution), is suitable for intramuscular or intravenous administration. The color of the reconstituted solution is colorless to light yellow.

Each vial contains colistimethate sodium or pentasodium colistinmethanesulfonate (150 mg colistin base activity) as a white to slightly yellow lyophilized cake. The sodium content is approximately 0.07 mg (0.003 mEq) of sodium per milligram of Colistin.

Colistimethate sodium is a polypeptide antibiotic with an approximate molecular weight of 1,750. The molecular formula is C58 H105 N16 Na5 O28 S5 and the structural formula is represented below:

structure
(click image for full-size original)
pentasodium colistinmethanesulfonate (colistimethate sodium) Dbu is 2, 4-diaminobutanoic acid, R is 5-methylheptyl in colistin A and 5-methylhexyl in colistin B

CLINICAL PHARMACOLOGY

Typical serum and urine levels following a single 150 mg dose of colistimethate IM or IV in normal adult subjects are shown in Figure 1.

graph
(click image for full-size original)

Higher serum levels were obtained at 10 minutes following IV administration. Serum concentration declined with a half-life of 2 to 3 hours following either intravenous or intramuscular administration in adults and in the pediatric population, including premature infants.

Average urine levels ranged from about 270 mcg/mL at 2 hours to about 15 mcg/mL at 8 hours after intravenous administration and from 200 to about 25 mcg/mL during a similar period following intramuscular administration.

Microbiology
Colistimethate sodium is a surface active agent which penetrates into and disrupts the bacterial cell membrane. It has been shown to have bactericidal activity against most strains of the following microorganisms, both in vitro and in clinical infections as described in INDICATIONS AND USAGE:

Item No.:RX871165 871165  NDC No.70594-0023-01 70594-023-01 7059402301 70594002301  UPC No.:3-70594-02301-4 370594-023014 370594023014 MPN 002301
Colistimethate 150Mg Vial
Item No.:RX871165 871165 NDC No.70594-0023-01 70594-023-01 7059402301 70594002301 UPC No.:3-70594-02301-4 370594-023014 370594023014 MPN 002301

BRAND: COLISTIMETHATE NDC: 42023-0131-01,42023013101 UPC: 3-42023-13101-6,342023131016 JHP Pharma
Colistimethate 150Mg Vial By JHP Pharma
BRAND: COLISTIMETHATE NDC: 42023-0131-01,42023013101 UPC: 3-42023-13101-6,342023131016 JHP Pharma

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
COLISTIN (COLISTIMETHATE
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Item No.:RX871165 871165  NDC No.70594-0023-01 70594-023-01 7059402301 70594002301  UPC No.:3-70594-02301-4 370594-023014 370594023014 MPN 002301
Colistimethate 150Mg Vial
Item No.:RX871165 871165 NDC No.70594-0023-01 70594-023-01 7059402301 70594002301 UPC No.:3-70594-02301-4 370594-023014 370594023014 MPN 002301

XELLIA PHARMA USA
XELLIA PHARMA USA
XELLIA PHARMA USA