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Rx Item-Adakveo (crizanlizumab-tmca) Injection BY Novartis Pharma

NDC No. 0078-0883-61 00078-0883-61 00078088361 0078088361 UPC/GTIN No. 3-00780-88361-0 300780-883610 300780883610 MPN No. 88361NDC No. 0078-0883-61 00078-0883-61 00078088361 0078088361 UPC/GTIN No. 3-00780-88361-0 300780-883610 300780883610 MPN No. 88361Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Rx Item-Adakveo (crizanlizumab-tmca) Injection BY Novartis Pharma

$2943.53$2799.00

NDC No. 0078-0883-61 00078-0883-61 00078088361 0078088361 UPC/GTIN No. 3-00780-88361-0 300780-883610 300780883610 MPN No. 88361 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order Rx Item. Other Name: Crizanlizumab-tmca for: Prevention of Vaso-Occlusive Crises (VOCs) in Sickle Cell Diseas

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These highlights do not include all the information needed to use ADAKVEO safely and effectively. See full prescribing information for ADAKVEO.

ADAKVEO� (crizanlizumab-tmca) injection, for intravenous use
Initial U.S. Approval: 2019
INDICATIONS AND USAGE

ADAKVEO is a selectin blocker indicated to reduce the frequency of vasoocclusive crises in adults and pediatric patients aged 16 years and older with sickle cell disease. (1)
DOSAGE AND ADMINISTRATION

Administer 5 mg/kg by intravenous infusion over a period of 30 minutes on Week 0, Week 2, and every 4 weeks thereafter. (2.1)

See Full Prescribing Information for instructions on preparation and administration. (2.2)
DOSAGE FORMS AND STRENGTHS

Injection: 100 mg/10 mL (10 mg/mL) solution in a single-dose vial. (3)
CONTRAINDICATIONS

None. (4)
WARNINGS AND PRECAUTIONS

Infusion-Related Reactions: Monitor patients for signs and symptoms. Discontinue ADAKVEO infusion for severe reactions and manage medically. (5.1)
Interference With Automated Platelet Counts (platelet clumping): Run test as soon as possible or use citrate tubes. (5.2)

ADVERSE REACTIONS

Most common adverse reactions (incidence > 10%) are nausea, arthralgia, back pain, and pyrexia. (6.1)


To report SUSPECTED ADVERSE REACTIONS, contact Novartis Pharmaceuticals Corporation at 1-888-669-6682 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
USE IN SPECIFIC POPULATIONS

Pregnancy: May cause fetal harm. (8.1)

See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.

Revised: 11/2019

NDC No. 0078-0883-61 00078-0883-61 00078088361 0078088361 UPC/GTIN No. 3-00780-88361-0 300780-883610 300780883610 MPN No. 88361
Rx Item-Adakveo (crizanlizumab-tmca) Inj
NDC No. 0078-0883-61 00078-0883-61 00078088361 0078088361 UPC/GTIN No. 3-00780-88361-0 300780-883610 300780883610 MPN No. 88361

NDC No. 0078-0883-61 00078-0883-61 00078088361 0078088361 UPC/GTIN No. 3-00780-88361-0 300780-883610 300780883610 MPN No. 88361
Rx Item-Adakveo (crizanlizumab-tmca) Inj
NDC No. 0078-0883-61 00078-0883-61 00078088361 0078088361 UPC/GTIN No. 3-00780-88361-0 300780-883610 300780883610 MPN No. 88361

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
AmericanPharmaWholesale.com
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop