L-TRYPTOPHAN, USP 1KG by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name TRYPTOPHAN (L) USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) L-Tryptophan, L(-)-Tryptophan; (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid; L-alphs-Amino-3-indolepropionic acid; Indole-3-alanine. Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Not a hazardous substance or mixture. Signal Word None Hazard Statement(s) N/A Pictogram(s) N/A Precautionary Statement(s) N/A Hazards Not Otherwise Classified No data available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name L-Tryptophan Common Name L-Tryptophan CAS Number 73-22-3 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice No data available If Inhaled If inhaled, remove to fresh air. If not breathing, give artif icial respiration. If breathing is dif f icult, give oxygen. Get medical attention.. In Case of Skin Contact Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used. In Case of Eye Contact Check f or and remove any contact lenses. In case of contact, immediately f lush eyes with plenty of water f or at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs. If Swallowed Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Most Important Symptoms and Effects No data available Section 5: Fire Fighting Measures Suitable Extinguishing Media SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, f og or f oam. Do not use water jet. Special Hazards Arising From the Substance/Mixture Flammability of the Product: May be combustible at high temperature. Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...). Slightly f lammable to f lammable in presence of heat. Nonf lammable in presence of oxidizing materials. Explosion Hazards in Presence of Various Substances: Slightly explosive in presence of open f lames and sparks. Non-explosive in presence of shocks. Special Remarks on Fire Hazards: As with most organic solids, f ire is possible at elevated temperatures. Special Remarks on Explosion Hazards: Fine dust dispersed in air in suf f icient concentrations, and in the presences of an ignition source is a potential dust explosion hazard. Special PPE and/or Precautions for Firefighters Wear self contained breathing apparatus f or f ire f ighting if necessary. Page 1 of 4 Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be suf f icient; consult a specialist BEFORE handling this product. Methods and Materials Used for Containment Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surf ace and dispose of according to local and regional authority requirements. Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surf ace and allow to evacuate through the sanitary system. Cleanup Procedures Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surf ace and dispose of according to local and regional authority requirements. Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surf ace and allow to evacuate through the sanitary system. Section 7: Handling and Storage Precautions for Safe Handling Precautions: Keep away from heat. Keep away from sources of ignition. Do not ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, acids. Conditions for Safe Storage Store in a closed container, at 22C ~25C in a dry and cool place and relative humidity 55~65%. Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters No data available Appropriate Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, f ume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. PPE - Eye/Face Protection Saf ety glasses PPE - Skin Protection Gloves. Full suit. Boots. PPE - Body Protection Lab coat and gloves. PPE - Respiratory Protection A self contained breathing apparatus should be used to avoid inhalation of the product. Dust respirator. Be sure to use an approved/certif ied respirator or equivalent. Section 9: Physical and Chemical Properties Appearance Solid. Crystalline solid. White. Upper/Lower Flammability or Explosive Limits No data available Odor Odorless Vapor Pressure No data available Odor Threshold No data available Vapor Density No data available pH (1% soln/water): 5.5-6.4 Relative Density No data available Melting Point/Freezing Point Melting point: 282 deg. C. Decomposition temperature: 289C (552.2F) Solubility Soluble in hot water. Partially soluble in cold water. Insoluble in diethyl ether. Slightly soluble in acetic acid. Solubility in water. Insoluble in chlorof orm. Soluble in hot alcohol and solutions of dilute acids, and alkali hydroxides. Initial Boiling Point and Boiling Range No data available Flash Point No data available Evaporation Rate No data available Flammability (Solid, Gas) No data available Partition Coefficient No data available Auto-Ignition Temperature No data available Decomposition Temperature No data available Viscosity No data available Page 2 of 4 Section 10: Stability and Reactivity Reactivity No data available Chemical Stability The product is stable. Possibility of Hazardous Reactions Polymerization: Will not occur. Conditions to Avoid Conditions of Instability: Excess heat, incompatible materials. Special Remarks on Reactivity: Protect from light Incompatible Materials Reactive with oxidizing agents, acids. Hazardous Decomposition Products Other decomposition products-No data available Section 11: Toxicological Information Acute Toxicity - LD50 Oral Acute oral toxicity (LD50): >16000 mg/kg [Rat]. Acute Toxicity - Inhalation Slightly hazardous in case of inhalation. May cause respiratory tract irritation. Acute Toxicity - Dermal Slightly hazardous in case of skin contact (irritant) Acute Toxicity - Eye May cause eye irritation. Skin Corrosion/Irritation Slightly hazardous in case of skin contact (irritant). May cause skin irritation. Serious Eye Damage/Irritation No data available Respiratory or Skin Sensitazation Slightly hazardous in case of skin contact (irritant) Germ Cell Mutagenicity MUTAGENIC EFFECTS: Mutagenic f or bacteria and/or yeast. May af f ect genetic material (mutagenic) on Humans. Carcinogenicity IARC No data available. Carcinogenicity ACGIH No data available. Carcinogenicity NTP No data available. Carcinogenicity OSHA No data available. Reproductive Toxicity No data available Specific Target Organ Toxicity - Single Exposure No data available Specific Target Organ Toxicity - Repeated Exposure No data available Aspiration Hazard No data available Section 12: Ecological Information Toxicity No data available Persistence and Degradability Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Bio-accumulative Potential The product itself and its products of degradation are not toxic. Mobility in Soil No data available Other Adverse Effects No data available Section 13: Disposal Considerations Waste Treatment Methods Product Waste must be disposed of in accordance with f ederal, state and local environmental control regulations.. Waste Treatment Methods Packaging Waste must be disposed of in accordance with f ederal, state and local environmental control regulations. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number Not dangerous goods. UN Proper Shipping Name N/A Transport Hazard Class(es) N/A Packaging Group N/A Environmental Hazards N/A Page 3 of 4 Section 15: Regulatory Information Federal and State Regulations: TSCA 8(b) inventory: L-Tryptophan Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances. Other Classif ications: WHMIS (Canada): Not controlled under WHMIS (Canada). DSCL (EEC): This product is not classif ied according to the EU regulations. S24/25- Avoid contact with skin and eyes. HMIS (U.S.A.): Health Hazard: 1 Fire Hazard: 1 Reactivity: 0 Personal Protection: E National Fire Protection Association (U.S.A.): Health: 1 Flammability: 1 Reactivity: 0 Personal Protection: E National Fire Protection Association (U.S.A.): Health: 1 Flammability: 1 Reactivity: 0 Specif ic hazard: Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certif ied respirator or equivalent. Saf ety glasses. Section 16: Other Information Additional Information N/A Prepared By Scarlotte Smith Revision Date 01/16/2019 17:20 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
