PHENTOLAMINE MESYLATE, USP 100GM by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name PHENTOLAMINE MESYLATE USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) 2-(N-[m-hydroxphenyl]-p-toluidnomethyl)imidazoline Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Skin irritation (Category 2), Eye irritation (Category 2), Specif ic target organ toxicity - single exposure (Category 3), Acute aquatic toxicity (Category 1), Chronic aquatic toxicity (Category 1) Signal Word Warning Hazard Statement(s) H302+H312 Harmf ul if swallowed Harmf ul in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H332 Harmf ul if inhaled H335 May cause respiratory irritation Pictogram(s) Precautionary Statement(s) P261 Avoid breathing dust/f ume/gas/mist/vapours/spray. P264 Wash hands thoroughly af ter handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/f ace protection. P301+P312 IF SWALLOWED Call a POISON CENTER or doctor/physician if you f eel unwell. P302+P352 IF ON SKIN Wash with soap and water. P304+P340 IF INHALED Remove victim to fresh air and keep at rest in a position comf ortable f or breathing. P305+P351+P338 IF IN EYES Rinse cautiously with water f or several minutes. Remove contact lenses if present and easy to do. continue rinsing. P312 Call a POISON CENTER or doctor/physician if you f eel unwell. P330 Rinse mouth. P332+P313 If skin irritation occurs Get medical advice/attention. P337+P313 If eye irritation persists Get medical advice/attention. P362 Take of f contaminated clothing and wash bef ore reuse. P403+P233 Store in a well ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container to an approved waste disposal plant. Hazards Not Otherwise Classified No data available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name 2-(N-[m-hydroxphenyl]-p-toluidnomethyl)imidazoline Common Name Phentolamine Mesylate CAS Number 65-28-1 Impurities and/or Stabilizing Additives No data available Page 1 of 4 Section 4: First Aid Measures General Advice Consult a physician. Show this saf ety data sheet to the doctor in attendance. Move out of dangerous area. If Inhaled If breathed in, move person into fresh air. If not breathing give artif icial respiration. Consult a physician. In Case of Skin Contact Wash of f with soap and plenty of water. Consult a physician. In Case of Eye Contact Rinse thoroughly with plenty of water f or at least 15 minutes and consult a physician. If Swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most Important Symptoms and Effects No data available Section 5: Fire Fighting Measures Suitable Extinguishing Media Use water spray, alcohol-resistant f oam, dry chemical and carbon dioxide. Special Hazards Arising From the Substance/Mixture No data available Special PPE and/or Precautions for Firefighters Wear self contained breathing apparatus f or f ire f ighting if necessary. Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Use personal protective equipment. Avoid dust f ormation. Avoid breathing dust. Ensure adequate ventilation. Methods and Materials Used for Containment Pick up and arrange disposal without creating dust. Keep in suitable, closed containers f or disposal. Cleanup Procedures Pick up arrange disposal without creating dust. Keep in suitable, closed containers f or disposal. Do not let product enter drains. Section 7: Handling and Storage Precautions for Safe Handling Avoid contact with skin and eyes. Avoid f ormation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust if f ormed. Normal measures f or preventive f ire protection. Conditions for Safe Storage Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters Contains no substances with occupational exposure limit values. Appropriate Engineering Controls Handle in accordance with good industrial hygiene and saf ety practice. Wash hands bef ore breaks and at the end of workday. PPE - Eye/Face Protection Saf ety glasses with side-shields conf orming to EN166. PPE - Skin Protection Handle with gloves. PPE - Body Protection Choose body protection according to the amount and concentration of the dangerous substance at the work place. Handle with gloves. PPE - Respiratory Protection Where risk assessment shows air-purif ying respirators are appropriate use a dust mask type N95 (US) or type P-1 (EN143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Page 2 of 4 Section 9: Physical and Chemical Properties Appearance Form: Powder Colour: No data available Upper/Lower Flammability or Explosive Limits No data available Odor No data available Vapor Pressure No data available Odor Threshold No data available Vapor Density No data available pH No data available Relative Density No data available Melting Point/Freezing Point Melting point 180-182�C (356-360�F)-lit Solubility No data available Initial Boiling Point and Boiling Range No data available Flash Point No data available Evaporation Rate No data available Flammability (Solid, Gas) No data available Partition Coefficient No data available Auto-Ignition Temperature No data available Decomposition Temperature No data available Viscosity No data available Section 10: Stability and Reactivity Reactivity No data available Chemical Stability Stable under recommended storage conditions. Possibility of Hazardous Reactions No data available Conditions to Avoid No data available Incompatible Materials Oxidizing agents Hazardous Decomposition Products Hazardous decomposition products f ormed under f ire conditions - Carbon oxides, nitrogen oxides, (NOx), Sulphur oxides. Section 11: Toxicological Information Acute Toxicity - LD50 Oral LD50 Intravenous-mouse-75 mg/kg Acute Toxicity - Inhalation No data available Acute Toxicity - Dermal No data available Acute Toxicity - Eye No data available Skin Corrosion/Irritation No data available Serious Eye Damage/Irritation No data available Respiratory or Skin Sensitazation No data available Germ Cell Mutagenicity No data available Carcinogenicity IARC No component of this product present at levels greater than 0.1% is identif ied as probable, possible or conf irmed human carcinogen by IARC. Carcinogenicity ACGIH No component of this product present at levels greater than 0.1% is identif ied as a carcinogen or potential carcinogen by ACGIH. Carcinogenicity NTP No component of this product present at levels greater than or equal to 0.1% is identif ied as a known or anticipated carcinogen by NTP. Carcinogenicity OSHA No component of this product present at levels greater than or equal to 0.1% is identif ied as a carcinogen or potential carcinogen by OSHA. Reproductive Toxicity Reproductive toxicity -rat - Intraperitoneal Maternal Ef f ects: Uterus, cervix, vagina. Specific Target Organ Toxicity - Single Exposure Inhalation - May cause respiratory irritation. Specific Target Organ Toxicity - Repeated Exposure No data available Aspiration Hazard No data available Page 3 of 4 Section 12: Ecological Information Toxicity No data available Persistence and Degradability No data available Bio-accumulative Potential No data available Mobility in Soil No data available Other Adverse Effects No data available Section 13: Disposal Considerations Waste Treatment Methods Product Observe all f ederal, state, and local environmental regulations. Contact a licensed prof essional waste disposal service to dispose of this material. Waste Treatment Methods Packaging Dispose of as unused product. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number Not dangerous goods. UN Proper Shipping Name N/A Transport Hazard Class(es) N/A Packaging Group N/A Environmental Hazards N/A Section 15: Regulatory Information OSHA Hazards: Target Organ Ef f ect, Irritant. DSL Status: This product contains the f ollowing components that are not Canadian DSL or NDSL list Phentolamine Mesylate CAS-No. 65-28-1 SARA 302 Components: SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components: SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313. SARA 311/312 Hazards: Acute Health Hazard, Chronic Health Hazard. Massachusetts Right To Know Components: No components are subject to the Massachusetts Right To Know Act. Pennsylvania Right To Know Components: Phentolamine Mesylate CAS-No. 65-28-1. New Jersey Right To Know Components: Phentolamine Mesylate CAS-No. 65-28-1 Calif ornia Prop. 65 Components: This product does not contain any chemicals know to State of Calif ornia to cause cancer, birth def ects, or any other reproductive harm. Section 16: Other Information Additional Information N/A Prepared By Lisa Russell Revision Date 01/10/2019 11:58 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
