NIACINAMIDE, USP 5KG by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name NIACINAMIDE USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) Nicotinamide, 3-Pyridinecarboxamide Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Skin irritation (Category 2), Serious eye damage/eye irritation (Category 2), Specif ic target organ toxicity - single exposure (Category 3), Specif ic target organ toxicity (repeated exposure) (Category 2) Signal Word Warning Hazard Statement(s) H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H336 May cause drowsiness or dizziness H373 May cause damage to organs through prolonged or repeated exposure Pictogram(s) Precautionary Statement(s) P260 Do not breathe dust/f ume/gas/mist/vapours/spray. P264 Wash hands thoroughly af ter handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/f ace protection. P302+P352 IF ON SKIN Wash with soap and water. P304+P340 IF INHALED Remove victim to fresh air and keep at rest in a position comf ortable f or breathing. P305+P351+P338 IF IN EYES Rinse cautiously with water f or several minutes. Remove contact lenses if present and easy to do. continue rinsing. P312 Call a POISON CENTER or doctor/physician if you f eel unwell. P314 Get Medical advice/attention if you f eel unwell. P321 Specif ic treatment (see on this label). P332+P313 If skin irritation occurs Get medical advice/attention. P337+P313 If eye irritation persists Get medical advice/attention. P362 Take of f contaminated clothing and wash bef ore reuse. P403 Store in a well ventilated place. P405 Store locked up. P501 Dispose of contents/container to an approved waste disposal plant. Hazards Not Otherwise Classified No data available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name Niacinamide Common Name Niacinamide CAS Number 98-92-0 Impurities and/or Stabilizing Additives No data available Page 1 of 4 Section 4: First Aid Measures General Advice Show this saf ety data sheet to the doctor in attendance. If Inhaled Move to fresh air. If breathing is dif f icult, give oxygen. If not breathing, give artif icial respiration.Consult a physician. In Case of Skin Contact Wash of f immediately with soap and plenty of water removing all contaminated clothes and shoes. Wash contaminated clothing bef ore reuse. Consult a physician In Case of Eye Contact Rinse immediately with plenty of water, also under the eyelids, f or at least 15 minutes. Consult a physician If Swallowed Rinse mouth. Never give anything by mouth to an unconscious person. Consult a physician. Most Important Symptoms and Effects No inf ormation available. Treat symptomatically. Section 5: Fire Fighting Measures Suitable Extinguishing Media Water spray. Carbon dioxide (CO2). Dry chemical. Alcohol-resistant f oam. Special Hazards Arising From the Substance/Mixture Thermal decomposition or combustion may produce hazardous gases and/or materials. Keep product and empty container away from heat and sources of ignition. Special PPE and/or Precautions for Firefighters As in any f ire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and f ull protective gear. Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Evacuate personnel to saf e areas. Ensure adequate ventilation. Use personal protective equipment. Avoid contact with skin, eyes and clothing. In case of insuf f icient ventilation, wear suitable respiratory equipment. Methods and Materials Used for Containment Local authorities should be advised if signif icant spillages cannot be contained. Prevent f urther leakage or spillage if saf e to do so. Do not allow material to contaminate ground water system. Prevent product from entering drains. Do not f lush into surf ace water or sanitary sewer system. Should not be released into the environment. Cleanup Procedures Evacuate personnel to saf e areas. Sweep up and shovel into suitable containers f or disposal. Avoid dust f ormation. Clean contaminated surf ace thoroughly. Section 7: Handling and Storage Precautions for Safe Handling Use only in an area equipped with a saf ety shower. Ensure that eyewash stations and saf ety showers are close to the workstation location. Ensure adequate ventilation. Do not breathe vapours/dust. Avoid contact with skin, eyes and clothing. Avoid repeated exposure. Conditions for Safe Storage Keep container tightly closed in a dry and well-ventilated place. Keep in properly labelled containers. Incompatible Materials Strong oxidizing agents. Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters This product does not contain any hazardous materials with occupational exposure limits established by the region specif ic regulatory bodies. Appropriate Engineering Controls Ensure adequate ventilation, especially in conf ined areas. Handle in accordance with good industrial hygiene and saf ety practice. PPE - Eye/Face Protection Tightly f itting saf ety goggles. PPE - Skin Protection Wear protective gloves and protective clothing. PPE - Body Protection Wear protective gloves and protective clothing. PPE - Respiratory Protection In case of insuf f icient ventilation, wear suitable respiratory equipment. Page 2 of 4 Section 9: Physical and Chemical Properties Appearance White Crystalline Powder Upper/Lower Flammability or Explosive Limits No inf ormation available Odor Characteristic Vapor Pressure 24 mmHg @ 25°C Odor Threshold No inf ormation available Vapor Density Not available pH No data available Relative Density No data available Melting Point/Freezing Point 128 - 131 °C Solubility Water Solubility 58.5g/100ml @ 25 °C Initial Boiling Point and Boiling Range 150 - 160 °C Flash Point 182 °C Evaporation Rate Not available Flammability (Solid, Gas) No inf ormation available Partition Coefficient Not available Auto-Ignition Temperature 480 °C Estimated Decomposition Temperature No data available Viscosity No inf ormation available Section 10: Stability and Reactivity Reactivity Not applicable. Chemical Stability Stable under normal conditions. Possibility of Hazardous Reactions None under normal processing Conditions to Avoid Heat, f lames and sparks. Avoid dust f ormation. Incompatible Materials Strong oxidizing agents. Hazardous Decomposition Products Carbon Oxides Nitrogen Oxides (NOx) Section 11: Toxicological Information Acute Toxicity - LD50 Oral LD50 Oral - rat - 3,500 mg/kg ATEmix (oral) 3500 mg/kg Acute Toxicity - Inhalation No data available Acute Toxicity - Dermal > 2000 mg/kg ( Rabbit ) Acute Toxicity - Eye Irritating to eyes. Avoid contact with eyes. Skin Corrosion/Irritation May be harmf ul by skin contact. Irritating to skin. Avoid contact with skin. Serious Eye Damage/Irritation Irritating to eyes. Avoid contact with eyes. Respiratory or Skin Sensitazation May be harmf ul by inhalation. Irritating to respiratory system. May cause irritation of the mucous membranes. Avoid breathing dust. Germ Cell Mutagenicity No data available Carcinogenicity IARC There are no known carcinogenic chemicals in this product. Carcinogenicity ACGIH There are no known carcinogenic chemicals in this product. Carcinogenicity NTP There are no known carcinogenic chemicals in this product. Carcinogenicity OSHA There are no known carcinogenic chemicals in this product. Reproductive Toxicity No inf ormation available. Specific Target Organ Toxicity - Single Exposure No inf ormation available Specific Target Organ Toxicity - Repeated Exposure No inf ormation available. Chronic Toxicity Avoid repeated exposure. Target Organ Ef f ects. Aspiration Hazard No inf ormation available Page 3 of 4 Section 12: Ecological Information Toxicity Water Flea Data: > 1000 mg/L EC50 Persistence and Degradability No inf ormation available Bio-accumulative Potential No inf ormation available Mobility in Soil No inf ormation available Other Adverse Effects No data available Section 13: Disposal Considerations Waste Treatment Methods Product Contact waste disposal services. Dispose of in accordance with local regulations. Waste Treatment Methods Packaging Dispose of in accordance with local regulations. Empty containers should be taken f or local recycling, recovery or waste disposal. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number Not dangerous goods. UN Proper Shipping Name N/A Transport Hazard Class(es) N/A Packaging Group N/A Environmental Hazards N/A Section 15: Regulatory Information U.S.A. (TSCA) Complies 100 % of the mixture consists of components(s) of unknown hazards to the aquatic environment Niacinamide USP 98-92-0 Canada (DSL) Complies EU (EINECS) Complies EU (ELINCS) Does not Comply Japan (ENCS) Complies China Complies Korea (KECL) Complies Philippines (PICCS) Complies Australia (AICS) Complies. SARA 313 Section 313 of Title III of the Superf und Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372. SARA 311/312 Hazardous Categorization China Complies Niacinamide USP Present (5)-736 Acute Health Hazard Yes Present Present Chronic Health Hazard Yes Present Present Fire Hazard No Australia (AICS) Complies Sudden Release of Pressure Hazard No Reactive Hazard CWA (Clean Water Act) This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42) Federal Regulations Chemical Name U.S.A. (TSCA) Canada (DSL) CERCLA This material, as supplied, does not contain any substances regulated as hazardous substances under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superf und Amendments and Reauthorization Act (SARA) (40 CFR 355). There may be specif ic reporting requirements at the local, regional, or state level pertaining to releases of this material Calif ornia Proposition 65 This product does not contain any Proposition 65 chemicals. Present Present - SARA 313 Section 313 of Title III of the Superf und Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372. State Right-to-Know This product does not contain any State Right-to-Know chemicals. EPA Pesticide Registration Number Not applicable WHMIS Statement This product has been classif ied in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the inf ormation required by the CPR. Section 16: Other Information Additional Information N/A Prepared By Lisa Russell Revision Date 01/10/2019 12:13 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
