METHOCEL K100M PREMIUM (HYPROMELLOSE 2208, USP (100,000 CPS)) 1KG by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name METHOCEL K100M PREMIUM USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) N/A Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Not classif ied. Signal Word None Hazard Statement(s) N/A Pictogram(s) N/A Precautionary Statement(s) N/A Hazards Not Otherwise Classified No data available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name N/A Common Name METHOCEL(TM) K100M Premium Hydroxypropyl Methylcellulose CAS Number 9004-65-3 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice CAUTION: Powdered material may f orm explosive dust-air mixture. Slipping hazard. Avoid temperatures above 130°C (266°F) If potential f or exposure exists ref er to Section 8 f or specif ic personal protective equipment. If Inhaled Move person to fresh air. If ef f ects occur, consult a physician. In Case of Skin Contact Wash skin with plenty of water. In Case of Eye Contact Flush eyes with plenty of water, rempve contact lenses af ter the f irst 1-2 minutes then continue f lushing f or several minutes. Only mechanical ef f ects expected. If ef f ects occur, consult a physician, pref erably an opthamologist. If Swallowed No emergency medical treatment necessary. Most Important Symptoms and Effects Aside from all the inf ormation f ound under Description of f irst aid measures (above) and Indication of immediate medical attention and special treatment needed (below), no additional symptoms and ef f ects are anticipated. Section 5: Fire Fighting Measures Suitable Extinguishing Media Water. Dry chemical f ire extinguishers. Carbon dioxide f ire extinguishers. Special Hazards Arising From the Substance/Mixture During a f ire, smoke may contain original material in addition to combustion products of varying composition which may be toxic and/or irritating. Combustion products may include and are not limited to: Carbon monoxide. Carbon dioxide. Unusual Fire and Explosion Hazards: Do not permit dust to accumulate. When suspended in air dust can pose an explosion hazard. Minimize ignition sources. If dust layers are exposed to elevated temperatures, spontaneous combustion may occur. Pneumatic conveying and other mechanical handling operations can generate combustible dust. To reduce the potential f or dust explosions, electrically bond and ground equipment and do not permit dust to accumulate. Dust can be ignited by static discharge. Special PPE and/or Precautions for Firefighters Wear positive-pressure self-contained breathing apparatus and protective f ire f ighting clothing (including f ire helmet, coat, trousers, boots, and gloves). If protective equipment is not available or not used, f ight f ire from a protected location or saf e distant. Page 1 of 4 Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Spilled material may cause a slipping hazard. Use appropriate saf ety equipment. For additional inf ormation, ref er to Section 8, Exposure controls and Personal Protection. Methods and Materials Used for Containment Contain spilled material if possible. Sweep up. Use care to minimize generation of airborne dust. Do not use water f or cleanup. Collect in suitable and properly labeled containers. See Section 13, Disposal Considerations, f or additional inf ormation. Cleanup Procedures Contain spilled material if possible. Sweep up. Use care to minimize generation of airborne dust. Do not use water f or cleanup. Collect in suitable and properly labeled containers. See Section 13, Disposal Considerations, f or additional inf ormation. Prevent from entering into soil, ditches, sewers, waterways and/or groundwater. See Section 12, Ecological Inf ormation. Section 7: Handling and Storage Precautions for Safe Handling Keep away from heat, sparks and f lames. No smoking, open f lames of sources of ignition in handling and storage area. Electrically ground and bond all equipment. Good housekeeping and controlling of dusts are necessary f or saf e handling of product. Pneumatic conveying and other mechanical handling operations can generate combustible dust. To reduce the potential f or dust explosions, electrically bond and ground equipment and do not permit dust to accumulate. Dust can be ignited by static discharge. See Section 8, EXPOSURE CONTROLS AND PERSONAL PROTECTION. Conditions for Safe Storage Store in a dry place. See Section 10 f or more specif ic inf ormation. Storage temperature: 5 - 35 °C Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters Component: Hydroxypropyl methyl cellulose List: Dow IHG Type: TWA Total dust Value: 10 mg/m3 Appropriate Engineering Controls Use local exhaust ventilation, or other engineering controls to maintain airborne levels below exposure limit requirements or guidelines. If there are no applicable exposure limit requirements or guidelines, general ventilation should be suf f icient f or most operations. Local exhaust ventilation may be necessary f or some operations. Use good personal hygiene. Do not consume or store f ood in the work area. Wash hands bef ore smoking or eating. PPE - Eye/Face Protection Use saf ety glasses with side-shields. If there is potential f or exposure to particles which could cause eye discomf ort, wear chemical goggles. PPE - Skin Protection Chemical protective gloves should not be needed when handling this material. Consistent with general hygienic practice f or any material, skin contact should be minimized. PPE - Body Protection No precautions other than clean body-covering clothing should be needed. Chemical protective gloves should not be needed when handling this material. Consistent with general hygienic practice f or any material, skin contact should be minimized. PPE - Respiratory Protection Respiratory protection should be worn when there is potential to exceed the exposure limit requirements or guidelines. If there is no applicable exposure limit requirements or guidelines, wear respiratory protection when adverse ef f ects, such as respiratory irritation or discomf ort have been experienced, or where indicated by your risk assessment process. For most conditions, no respiratory protection should be needed, however, in dusty atmospheres, use and approved particle respirator. The f ollowing should be ef f ective types of air-purif ying respirators: Particulate f ilter. Section 9: Physical and Chemical Properties Appearance Form: Powder Colour: White to of f-white Upper/Lower Flammability or Explosive Limits No data available Odor Odorless Vapor Pressure No data available Odor Threshold No data available Vapor Density No data available pH No data available Relative Density No data available Melting Point/Freezing Point No data available Solubility Solubility in water completely soluble in water Initial Boiling Point and Boiling Range No data available Flash Point No data available Evaporation Rate No data available Flammability (Solid, Gas) No data available Partition Coefficient No data available Auto-Ignition Temperature No data available Decomposition Temperature No data available Viscosity No data available Page 2 of 4 Section 10: Stability and Reactivity Reactivity No dangerous reaction known under conditions of normal use. Chemical Stability Stable under recommended storage conditions. Possibility of Hazardous Reactions Polymerization will not occur. Conditions to Avoid Avoid temperatures above 130 °C (266 °F). Exposure to elevated temperatures can cause product to decompose. Avoid static discharge. Incompatible Materials Avoid contact with oxidizing materials. Avoid contact with: Strong acids. Strong bases. Hazardous Decomposition Products Decomposition products depend upon temperature, air supply and the presence of other materials. Section 11: Toxicological Information Acute Toxicity - LD50 Oral LD50, rat > 10,000 mg/kg Acute Toxicity - Inhalation The LC50 has not been determined. Acute Toxicity - Dermal The dermal LD50 has not been determined. Acute Toxicity - Eye Solid or dust may cause irritation or corneal injury due to mechanical action. Skin Corrosion/Irritation Essentially nonirritating to skin. Serious Eye Damage/Irritation Solid or dust may cause irritation or corneal injury due to mechanical action. Respiratory or Skin Sensitazation A similar material did not cause allergic skin reactions when tested in humans. Germ Cell Mutagenicity No data available Carcinogenicity IARC No data available Carcinogenicity ACGIH No data available Carcinogenicity NTP No data available Carcinogenicity OSHA No data available Reproductive Toxicity In animal studies, a similar cellulosic has been shown not to interf ere with reproduction. Specific Target Organ Toxicity - Single Exposure No data available Specific Target Organ Toxicity - Repeated Exposure Repeated ingestion of similar cellulosics by humans has not resulted in known signif icant adverse. Aspiration Hazard Based on physical properties, not likely to be an aspiration hazard. Section 12: Ecological Information Toxicity Material is practically non-toxic to aquatic organisms on an acute basis (LC50/EC50/EL50/LL50 >100 mg/L in the most sensitive species tested). Persistence and Degradability Material is expected to biodegrade only very slowly (in the environment). Fails to pass OECD/EEC tests f or ready biodegradability. Bio-accumulative Potential No bioconcentration is expected because of the relatively high molecular weight (MW greater than 1000). Mobility in Soil No data available Other Adverse Effects No data available Section 13: Disposal Considerations Waste Treatment Methods Product DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All disposal practices must be in compliance with all Federal, State/Provincial and local laws and regulations. Regulations may vary in dif f erent locations. Waste characterizations and compliance with applicable laws are the responsibility solely of the waste generator. AS YOUR SUPPLIER, WE HAVE NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF PARTIES HANDLING OR USING THIS MATERIAL. THE INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION AS DESCRIBED IN MSDS SECTION: Composition Inf ormation. FOR UNUSED & UNCONTAMINATED PRODUCT, the pref erred options include sending to a licensed, permitted: Recycler. Reclaimer. Incinerator or other thermal destruction device. Landf ill. Waste Treatment Methods Packaging DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All disposal practices must be in compliance with all Federal, State/Provincial and local laws and regulations. Regulations may vary in dif f erent locations. Waste characterizations and compliance with applicable laws are the responsibility solely of the waste generator. AS YOUR SUPPLIER, WE HAVE NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF PARTIES HANDLING OR USING THIS MATERIAL. THE INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION AS DESCRIBED IN MSDS SECTION: Composition Inf ormation. FOR UNUSED & UNCONTAMINATED PRODUCT, the pref erred options include sending to a licensed, permitted: Recycler. Reclaimer. Incinerator or other thermal destruction device. Landf ill. Special Precautions Landfill or Incinerations No data available Other Information No data available Page 3 of 4 Section 14: Transport Information UN Number Not dangerous goods. UN Proper Shipping Name N/A Transport Hazard Class(es) N/A Packaging Group N/A Environmental Hazards N/A Section 15: Regulatory Information OSHA Hazard Communication Standard This product is not a "Hazardous Chemical" as def ined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200. Superf und Amendments and Reauthorization Act of 1986 Title III (Emergency Planning and Community Right-to-Know Act of 1986) Sections 311 and 312 Immediate (Acute) Health Hazard: No Delayed (Chronic) Health Hazard: No Fire Hazard: No Reactive Hazard: No Sudden Release of Pressure Hazard: No Superf und Amendments and Reauthorization Act of 1986 Title III (Emergency Planning and Community Right-to-Know Act of 1986) Section 313 To the best of our knowledge, this product does not contain chemicals at levels which require reporting under this statute. Pennsylvania (Worker and Community Right-To-Know Act): Pennsylvania Hazardous Substances List and/or Pennsylvania Environmental Hazardous Substance List: To the best of our knowledge, this product does not contain chemicals at levels which require reporting under this statute. Pennsylvania (Worker and Community Right-To-Know Act): Pennsylvania Special Hazardous Substances List: To the best of our knowledge, this product does not contain chemicals at levels which require reporting under this statute. Calif ornia Proposition 65 (Saf e Drinking Water and Toxic Enf orcement Act of 1986) This product contains no listed substances known to the State of Calif ornia to cause cancer, birth def ects or other reproductive harm, at levels which would require a warning under the statute. US. Toxic Substances Control Act All components of this product are on the TSCA Inventory or are exempt from TSCA Inventory requirements under 40 CFR 720.30 CEPA - Domestic Substances List (DSL) All substances contained in this product are listed on the Canadian Domestic Substances List (DSL) or are not required to be listed. Section 16: Other Information Additional Information Prepared By Lisa Russell Revision Date 01/08/2019 14:21 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
