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Rx Item-Liothyronine Sodium USP 5gm By Letco Medical

Liothyronine Sodium, USP 5gm By Letco Medical Item No.Letco686347 NDC No. 62991-1096-03 62991109603 Category: Rx This Prescription Item Can Only Be Ordered By Physicians, Pharmacies, Dentists, WholesaJust change the quantity and save!Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.COMPOUNDING ITEMS SPECIALIST

Rx Item-Liothyronine Sodium USP 5gm By Letco Medical

$1892.18$1229.71

Item No.:RX-LETCO686347, Liothyronine Sodium, USP 5gm By Letco Medical Item No.Letco686347 NDC No. 62991-1096-03 62991109603 Category: Rx This Prescription Item Can Only Be Ordered By Physicians, Pharmacies, Dentists, Wholesalers, Hospitals, Government, Va, Physician Assistants, Nurse Practitioners , Podiatrists, Opticians, Optometrists, Veterinarians, Naturalists, Licensed Labs, Physical Therapists & Pharmacists In Their Scope Of Practice. UPC No.: 28100020102900

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LIOTHYRONINE SODIUM, USP 5GM by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name Liothyronine Sodium Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) L-Tyrosine, O-(4-hydroxy -3-iodophenyl)-3, 5-diiodo-, monosodium salt. Monosodium L-3-[4-(4-hydroxy-3- iodophenoxy)-3, 5- diiodophenyl] alanine Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Acute Toxicity (Category 3), Acute Toxicity (Category 4) Signal Word Danger Hazard Statement(s) H301 Toxic if swallowed H311 Toxic in contact with skin H332 Harmf ul if inhaled Pictogram(s) Precautionary Statement(s) P261 Avoid breathing dust/f ume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/f ace protection. P301+P310 IF SWALLOWED Immediately call a POISON CENTER or doctor/physician. P405 Store locked up. P501 Dispose of contents/container to an approved waste disposal plant. Hazards Not Otherwise Classified N/A Ingredient(s) with Unknown Toxicity N/A Section 3: Composition/Information on Ingredients Chemical Name L-Tyrosine, O-(4-hydroxy -3-iodophenyl)-3, 5-diiodo-, monosodium salt.  Monosodium L-3-[4-(4-hydroxy-3- iodophenoxy)-3, 5- diiodophenyl] alanine Common Name Liothyronine Sodium CAS Number 55-06-1 Impurities and/or Stabilizing Additives N/A Section 4: First Aid Measures General Advice Not available. If Inhaled Slight inhalation allows the victim to rest in a well ventilated area. Seek medical attention. Hazardous inhalation remove source of contamination or move victim to fresh air. If breathing has stopped, cardiopulmonary resuscitation (CPR) immediately (use protective mask with one way valve). If breathing is dif f icult give oxygen. Seek medical attention. In Case of Skin Contact Skin contact f lushes the contact area with lukewarm running water. Hazardous skin contact f lushes the contact area with lukewarm running water f or at least 15 minutes. Remove contaminated clothing, taking care not to spread the chemical. Seek medical attention if irritation persists. In Case of Eye Contact Eye contact immediately f lush eyes with running water f or at least 15 minutes, keeping eye lids open. Take care not to rinse contaminated water into the non-af f ected eye. Always seek medical attention f or accidents involving the eyes. If Swallowed Slight ingestion may cause irritation. Flush out mouth with water. Hazardous ingestion Never give anything by mouth if victim is rapidly losing consciousness or is unconscious convulsing. Rinse mouth thoroughly with water. If breathing has stopped, trained personnel should begin artif icial respiration (use protective mask with one â??way valve), or if the heart has stopped, cardiopulmonary resuscitation (CPR) immediately. Seek medical attention. Adults rarely experience symptoms with one time ingestions of up to 3 mg, but ingestion of larger amounts can be serious. Most Important Symptoms and Effects Routes of entry eye contact, skin contact, inhalation, ingestion Toxicity data RTECS#:XP3583000 General observations Behavior (headache, coma) Cardiac (change in rate) Gastrointestinal (hyper motility, diarrhea)Overdose treatment includes the f ollowing. 1. For recent ingestions, empty the stomach by induced vomiting. Charcoal instillation may be usef ul up to 3 to 4 hours f ollowing ingestion. 2. Administer cardiac glycosides if congestive heart f ailure develops. 3. Use appropriate measures to control f ever, hypoglycemia, and f luid loss. 4. Give ant adrenergic agents such as propranolol f or treatment of increased sympathetic activity. 5. Intravenous hydrocortisone can be used to partially inhibit conversion of T4 to T3. Page 1 of 5 Section 5: Fire Fighting Measures Suitable Extinguishing Media Extinguishing media Water spray, dry chemical, carbon dioxide, or f oam as appropriate f or surrounding f ire and materials. Special Hazards Arising From the Substance/Mixture Risks of explosion of the product in presence of mechanical impact: Not available Risks of explosion of the product in presence of static discharger: Fine air bone dust can be ignited by static discharge. Flammability emits toxic f umes under f ire conditions. Fire degradation products these products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), halogenated compounds. Special PPE and/or Precautions for Firefighters Special f iref ighting procedures as with all f ires, evacuate personnel to a saf e area. Firef ighters should use selfcontained breathing equipment and protective clothing Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Protective clothing in case of large spill Hooded f ull suit â?? Tyvek coveralls or equivalent air purif ying respirator with particulate cartridge P100 (HEPA). Boots gloves. Methods and Materials Used for Containment Small spill and leak Vacuum or sweep up spillage. Avoid dust. Place spillage in appropriate labeled solid pharmaceutical waste class 261N container f or waste disposal. Wash contaminated clothing bef ore reuse. Ventilate area and wash spill site. Follow appropriate saf e work practice. Large spill and leak Use a shovel put the material into a appropriate labeled waste disposal container. Finish cleaning by spreading water on the contaminated surf ace. Label and dispose as pharmaceutical waste class 261N. Follow appropriate saf e work practices. Cleanup Procedures Small spill and leak Vacuum or sweep up spillage. Avoid dust. Place spillage in appropriate labeled solid pharmaceutical waste class 261N container f or waste disposal. Wash contaminated clothing bef ore reuse. Ventilate area and wash spill site. Follow appropriate saf e work practice. Large spill and leak Use a shovel put the material into a appropriate labeled waste disposal container. Finish cleaning by spreading water on the contaminated surf ace. Label and dispose as pharmaceutical waste class 261N. Follow appropriate saf e work practices. Section 7: Handling and Storage Precautions for Safe Handling Use with adequate dust control. In case of insuf f icient ventilation, wear suitable respiratory equipment. Avoid inhalation, skin and eye contact. Wash thoroughly af ter handling. Dispose as pharmaceutical waste 261N. Conditions for Safe Storage Material shall be packed in HDPE container. Preserve in tight containers, store at 2-8�?°C (As per USP monograph). In an air tight container, Protected from light, at a temperature between 2-8�?ºC (As per Ph. Eur. monograph). Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters Not established. Appropriate Engineering Controls Exposure to This material can be controlled in many ways. The measures appropriate f or a particular worksite depend on how this material is used and on the extent of exposure. This general inf ormation can be used to help develop specif ic control measures. Ensure that control systems are properly designed and maintained. Comply with occupational, environmental, f ire and other applicable regulations. Engineering methods to control hazardous conditions are pref erred. Methods include mechanical (local exhaust) ventilation, process or personnel enclosure and control of process conditions. Administrative controls and personnel enclosure and control of process conditions. Administrative controls and personnel protective equipment may also be required. Supply suf f icient replacement air to make up f or air removed by exhaust system. Remove contaminated clothing promptly. Launder bef ore re wearing. Inf orm laundry personnel of contaminants hazards. Do not eat, drink or smoke in work areas. Wash hands to thoroughly af ter handling this material. Maintain good housekeeping. PPE - Eye/Face Protection Saf ety goggles PPE - Skin Protection Impervious gloves (eg. Natural or butyl rubber, nitrile, neoprene or PVC). Azico Biophore standards require that all latex gloves should be medical grade hypoallergenic gloves or those who have type 1 hyper sensitive reaction to latex nitrile gloves are recommended. Hooded f ull impervious suit and boots (eg. Shield 2 or Tyvek brands and/or equivalent resistant protective clothing). Have a saf ety shower/eye wash f ountain readily available the immediate work area. PPE - Body Protection Full suit with hood, or disposable/washable cover all. Boots rubber. Guidelines: GOOD: natural, butyl or styrenebutadiene rubber (SBR), neoprene, nitrile, polyvinyl chloride (PVC), polyurethane, nitrile + PVC, neoprene + SBR, neoprene + natural rubber, SBR/neoprene NOTE: Resistance of specif ic materials can vary from product to product. Evaluate resistance under conditions of use and maintain clothing caref ully. PPE - Respiratory Protection Half f ace piece Air purif ying respirator with particulate cartridge P100 (HEPA) (Less than 1g). Powdered air purif ying respirator (PAPR) with particulate cartridge P100 (HEPA) (greater than 1g). Where barrier technology or a high degree of process contaminant exists, respiratory protection may not be required. When working with quantities less than 1 kg and in the absence of appropriate local exhaust ventilation (LEV) or other containment, a half f ace piece Air purif ying respirator with particulate cartridge P100 (HEPA) and goggles is adequate. When working with quantities greater than 1 kg and in the absence of local exhaust ventilation (LEV) or other containment, a powdered Air purif ying respirator (PAPR) with particulate cartridge P100 (HEPA) and helmet/hooder supplied air respirator is recommended. The specif ic respirator selected must be based on contamination levels f ound in the work place, the specif ic operation and not exceed the working limits of the respirator. When perf orming cleaning activities ref er to appropriate cleaning solution MSDS. NOTE: barrier technology utilizes physical containment f acilities and methods to prevent human contact with a chemical or biological material with hazardous properties. Examples include glove boxes, f lexible isolators, robotics or remote operation. Page 2 of 5 Section 9: Physical and Chemical Properties Appearance Solid. Light tan, odorless, crystalline powder. Upper/Lower Flammability or Explosive Limits No data available. Odor No data available. Vapor Pressure Not applicable. Odor Threshold Not available. Vapor Density Not applicable. pH not available Relative Density No data available. Melting Point/Freezing Point Decomposes. Solubility Very slightly Soluble in cold water Initial Boiling Point and Boiling Range Not applicable. Flash Point No data available. Evaporation Rate Not available Flammability (Solid, Gas) No data available. Partition Coefficient No data available. Auto-Ignition Temperature No data available. Decomposition Temperature No data available. Viscosity No data available. Section 10: Stability and Reactivity Reactivity Strong oxidizing agents, strong acids Chemical Stability The product is stable. Possibility of Hazardous Reactions The product is stable. Reactivity/Incompatibility: Strong oxidizing agents, strong acids. Conditions to Avoid Strong oxidizing agents, strong acids. Incompatible Materials Strong oxidizing agents, strong acids Hazardous Decomposition Products Hazardous decomposition products these products are halogenated compounds Page 3 of 5 Section 11: Toxicological Information Acute Toxicity - LD50 Oral Hazardous in case of ingestion. Acute Toxicity - Inhalation Hazardous in case of inhalation (lung irritant). Acute Toxicity - Dermal Very hazardous in case of skin contact (irritant). Skin inf lammation is characterized by itching, scaling, reddening or occasionally blistering. Acute Toxicity - Eye Inf lammation of the eye is characterized by redness, watering, and itching. Skin Corrosion/Irritation Slightly hazardous in case of skin contact (permeator). Skin inf lammation is characterized by itching, scaling, reddening or occasionally blistering. Serious Eye Damage/Irritation Inf lammation of the eye is characterized by redness, watering, and itching. Respiratory or Skin Sensitazation Slightly hazardous in case of skin contact (permeator). Germ Cell Mutagenicity No inf ormation available Carcinogenicity IARC This product is not listed in IARC monographs, the NTP annual reports or the current ACGIH TLVs as a carcinogen or potential carcinogen. Carcinogenicity ACGIH This product is not listed in IARC monographs, the NTP annual reports or the current ACGIH TLVs as a carcinogen or potential carcinogen. Carcinogenicity NTP This product is not listed in IARC monographs, the NTP annual reports or the current ACGIH TLVs as a carcinogen or potential carcinogen. Carcinogenicity OSHA It is not regulated by OSHA as a carcinogen. Reproductive Toxicity no inf ormation available. Teratogenicity pregnancy category: A clinical experience humans has shown that appropriate therapeutic use of thyroid hormones does not cause adverse ef f ects the f etus. Specific Target Organ Toxicity - Single Exposure No inf ormation available Specific Target Organ Toxicity - Repeated Exposure No inf ormation available Aspiration Hazard No inf ormation available Section 12: Ecological Information Toxicity Not available Persistence and Degradability Toxicity of the products of bio degradation: degradation are as toxicas the product itself . Special remarks Bio-accumulative Potential Product of bio degradation: possibly hazardous short term degradation products are not likely, however, long term degradation products may arise. Mobility in Soil Not available Other Adverse Effects Not available Section 13: Disposal Considerations Waste Treatment Methods Product Collect in sealed containers and place in appropriate labeled pharmaceuticals solid waste class 261N container according to internal and external standards and procedures. Follow all appropriate saf e work procedures and f ederal, provincial and local regulations f or disposal. Use only licensed disposal and waste hauling companies. Waste Treatment Methods Packaging Collect in sealed containers and place in appropriate labeled pharmaceuticals solid waste class 261N container according to internal and external standards and procedures. Follow all appropriate saf e work procedures and f ederal, provincial and local regulations f or disposal. Use only licensed disposal and waste hauling companies. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number Not dangerous goods. UN Proper Shipping Name N/A Transport Hazard Class(es) N/A Packaging Group N/A Environmental Hazards N/A Section 15: Regulatory Information USA Classif ications NATIONAL FIRE PROTECTION ASSOCIATION (NFPA) HAZARD INDEX: NFPA-HEALTH-blue : 1-slightly hazardous to health NFPAFLAMMABILITY-red: 1-materails that must be preheated bef ore ignition can occur NFPA-REACTIVITY-yellow: 0-normally stable Hazardous material inf ormation system (U.S.A) HCS (Hazardous communication system). (OSHA. U.S.A) HCS CLASS: Harmf ul DOT (Department of Transportation) (U.S.A) (Pictograms) Not a DOT controlled material. European Classif ications DSCL (Dangerous substances classif ications) (Europe) (Pictograms) DSCL Risk (R) and saf ety (S) Phrases R20/21/22-Harmf ul by inhalation, in contact with skin and if swallowed. R48-Danger of serious damage to health by prolonged exposure. S36- Wear suitable protective clothing. ADR (European agreement of Dangerous goods by road) (Pictograms) Not controlled under ADR (Europe) Other regulations Not available Page 4 of 5 Section 16: Other Information Additional Information Medical conditions aggravated by exposure: l hypersensitivity to material, adrenocortical insuf f iciency, cardiovascular disease, hypertension, diabetes mellitus, hyperthyroidism, pituitary insuf f iciency, thyrotoxicosis, and long standing hypothyroidism or my edema. Short term ef f ects and signs & symptoms of over exposure Possible eye, skin, gastrointestinal and/or respiratory tract irritation. The usual oral adult dose of Liothyronine (as the sodium salt) is 0.05mg as a single daily dose, which may be gradually increased up to 0.15 mg. NOTE: signs of toxicity may be delayed as long as 5 â?? 11 days af ter ingestion of Liothyronine. Possible allergic reaction to material of inhaled, ingested or in contact with skin. Ef f ects from overdose can be delayed f or several days and may include changes in appetite, changes in menstrual periods, sensitivity to heat, weight loss, palpitations, rapid and irregular pulse, headache, dizziness hand tremors nervousness or irritability, insomnia, delirium, leg cramps, shortness of breath, chest pain, sweating, high f ever, vomiting, diarrhea, seizures, collapse and coma. Remark The above adverse ef f ects are based on clinical studies when the product was taken orally Prepared By Lisa Russell Revision Date 01/03/2019 14:49 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 5 of 5

Liothyronine Sodium, USP 5gm By Letco Medical Item No.Letco686347 NDC No. 62991-1096-03 62991109603 Category: Rx This Prescription Item Can Only Be Ordered By Physicians, Pharmacies, Dentists, Wholesa
LIOTHYRONINE SODIUM, USP 5GM by Letco Me
Liothyronine Sodium, USP 5gm By Letco Medical Item No.Letco686347 NDC No. 62991-1096-03 62991109603 Category: Rx This Prescription Item Can Only Be Ordered By Physicians, Pharmacies, Dentists, Wholesa

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

COMPOUNDING ITEMS SPECIALIST
LETCO MEDICAL
COMPOUNDING ITEMS SPECIALIST