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Rx Item-Hydroquinone USP 500gm By Letco Medical

Hydroquinone USP 500gm By Letco Medical Item No.Letco685368 NDC No. 62991-1196-03 62991119603 Category: Reagents Reagents UPC No.: 90872010002900Just change the quantity and save!Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.COMPOUNDING ITEMS SPECIALIST

Rx Item-Hydroquinone USP 500gm By Letco Medical

$6710.00$171.43

Item No.:RX-LETCO685368, Hydroquinone USP 500gm By Letco Medical Item No.Letco685368 NDC No. 62991-1196-03 62991119603 Category: Reagents Reagents UPC No.: 90872010002900

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HYDROQUINONE USP 500GM by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name Hydroquinone Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) 116 Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Acute toxicity, oral (Category 4), Skin corrosion/irritation (Cateogory 2), Serious eye damage/eye irritation (Category 1), Sensitization, skin (Category 1), Germ cell mutagenicity (Category 2), Carcinogenicity (Category 2) Signal Word Danger Hazard Statement(s) H302 Harmf ul if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H341 Suspected of causing genetic def ects H351 Suspected of causing cancer Pictogram(s) Precautionary Statement(s) P201 Obtain special instructions bef ore use. P202 Do not handle until all saf ety precautions have been read and understood. P264 Wash hands thoroughly af ter handling. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/f ace protection. P301+P312 IF SWALLOWED Call a POISON CENTER or doctor/physician if you f eel unwell. P302+P352 IF ON SKIN Wash with soap and water. P305+P351+P338 IF IN EYES Rinse cautiously with water f or several minutes. Remove contact lenses if present and easy to do. continue rinsing. P308+P313 IF exposed or concerned Get medical advice/attention. P310 Immediately call a POISON CENTER or doctor/physician. P330 Rinse mouth. P333+P313 If skin irritation or a rash occurs Get medical advice/attention. P362 Take of f contaminated clothing and wash bef ore reuse. P405 Store locked up. P501 Dispose of contents/container to an approved waste disposal plant. Hazards Not Otherwise Classified Not classif ied. Ingredient(s) with Unknown Toxicity None known Section 3: Composition/Information on Ingredients Chemical Name 1,4-Benzenediol Common Name Hydroquinone CAS Number 123-31-9 Impurities and/or Stabilizing Additives N/A Page 1 of 5 Section 4: First Aid Measures General Advice Remove from exposure. Remove contaminated clothing. For treatment advice, seek guidance from an occupational health physician or other licensed health-care provider f amiliar with workplace chemical exposures. In the United States, the national poison control center phone number is 1-800-222-1222. If person is not breathing, give artif icial respiration. If breathing is dif f icult, give oxygen if available. Persons developing serious hypersensitivity (anaphylactic) reactions must receive immediate medical attention. If Inhaled Move to fresh air. Call a physician if symptoms develop or persist. In Case of Skin Contact Remove contaminated clothing. Wash of f with soap and plenty of water. For minor skin contact, avoid spreading material on unaf f ected skin. If skin irritation or rash occurs: Get medical advice/attention. In Case of Eye Contact Rinse cautiously with water f or several minutes. Remove contact lenses, if present and easy to do.Continue rinsing. Call a physician or poison control center immediately. If Swallowed IF SWALLOWED: Call a POISON CENTER or doctor/physician if you f eel unwell. Rinse mouth. Most Important Symptoms and Effects Irritation of eyes, skin, and mucous membranes. May cause allergic skin reaction. Indication of immediate medical attention and special treatment needed: Treatment of overdose should be symptomatic and supportive and may include the f ollowing: 1. Immediately dilute with water or milk. 2. Induced vomiting is NOT recommended. 3. Administer activated charcoal as a slurry. 4. Perf orm gastric lavage soon af ter ingestion. Protect airway by placement in Trendelenburg and lef t lateral decubitus position or by endotracheal intubation. Control any seizures f irst. 5. For seizures, administer intravenous diazepam or lorazepam. If seizures recur, consider phenobarbital. Monitor f or hypotension, dysrhythmias, respiratory depression, and need f or endotracheal intubation. Evaluate f or hypoglycemia, electrolyte disturbances, and hypoxia. 6. For methemoglobinemia, slowly administer intravenous methylene blue in symptomatic patients. Additional doses my be required. Section 5: Fire Fighting Measures Suitable Extinguishing Media Use f ire-extinguishing media appropriate f or surrounding materials. Water. Foam. Dry chemical or CO2. Special Hazards Arising From the Substance/Mixture No unusual f ire or explosion hazards noted. Special PPE and/or Precautions for Firefighters Wear suitable protective equipment. Use water spray to cool unopened containers. As with all f ires, evacuate personnel to a saf e area. Firef ighters should use self-contained breathing equipment and protective clothing. Specif ic methods Use standard f iref ighting procedures and consider the hazards of other involved materials. Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Keep unnecessary personnel away. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Ensure adequate ventilation. Avoid inhalation of dust from the spilled material. Wear appropriate personal protective equipment. Methods and Materials Used for Containment Sweep up or vacuum up spillage and collect in suitable container f or disposal. Avoid the generation of dusts during clean-up. For waste disposal, see section 13 of the SDS. Clean surf ace thoroughly to remove residual contamination. Cleanup Procedures Sweep up or vacuum up spillage and collect in suitable container f or disposal. Avoid the generation of dusts during clean-up. For waste disposal, see section 13 of the SDS. Clean surf ace thoroughly to remove residual contamination. Section 7: Handling and Storage Precautions for Safe Handling As a general rule, when handling the sample, avoid all contact and inhalation of dust, mists, and/or vapors associated with the material. Clean equipment and work surf aces with suitable detergent or solvent af ter use. Af ter removing gloves, wash hands and other exposed skin thoroughly. Use of a designated area is recommended f or handling of potent materials. Conditions for Safe Storage Store in tight container as def ined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity. Page 2 of 5 Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters US. OSHA Table Z-1 Limits f or Air Contaminants (29 CFR 1910.1000): Hydroquinone (CAS 123-31-9) PEL 2 mg/m3. US. NIOSH: Pocket Guide to Chemical Hazards: Hydroquinone (CAS 123-31-9) Ceiling 2 mg/m3. US. ACGIH Threshold Limit Values: Hydroquinone (CAS 123-31-9) TWA 1 mg/m3 Biological limit values No biological exposure limits noted f or the ingredient(s). Appropriate Engineering Controls Airborne exposure should be controlled primarily by engineering controls such as general dilution ventilation, local exhaust ventilation, or process enclosure. Local exhaust ventilation is generally pref erred to general exhaust because it can control the contaminant at its source, preventing dispersion into the work area. An industrial hygiene survey involving air monitoring may be used to determine the ef f ectiveness of engineering controls. Ef f ectiveness of engineering controls intended f or use with highly potent materials should be assessed by use of nontoxic surrogate materials. Local exhaust ventilation such as a laboratory f ume hood or other vented enclosure is recommended, particularly f or grinding, crushing, weighing, or other dust-generating procedures. General hygiene considerations Handle in accordance with good industrial hygiene and saf ety practice. PPE - Eye/Face Protection Saf ety glasses with sideshields are recommended. Face shields or goggles may be required if splash potential exists or if corrosive materials are present. Approved eye protection (e.g., bearing the ANSI Z87 or CSA stamp) is pref erred. Maintain eyewash f acilities in the work area. PPE - Skin Protection Chemically compatible gloves. For handling solutions, ensure that the glove material is protective against the solvent being used. Use handling practices that minimize direct hand contact. Employees who are sensitive to natural rubber (latex) should use nitrile or other synthetic nonlatex gloves. Use of powdered latex gloves should be avoided due to the risk of latex allergy. To reduce the risk of contamination of skin and surf aces, wear two pairs of gloves. Remove the outer gloves af ter handling and cleanup of the material, and remove the inner gloves only af ter removing other personal protective equipment. PPE - Body Protection For handling of laboratory scale quantities, a disposable lab coat or isolation gown over street clothes is recommended. Where signif icant quantities are handled, work clothing and booties may be necessary to prevent takehome contamination. PPE - Respiratory Protection Where respirators are deemed necessary to reduce or control occupational exposures, use NIOSH-approved respiratory protection and have an ef f ective respirator program in place (applicable U.S. regulation OSHA 29 CFR 1910.134). Section 9: Physical and Chemical Properties Appearance Tan, gray, colorless or white needles or crystals. Upper/Lower Flammability or Explosive Limits Not available. Odor Odorless. Vapor Pressure 48 Odor Threshold Not available. Vapor Density 3.81 (air=1) pH 3.7 (7% concentration) Relative Density Not available. Melting Point/Freezing Point 77 Solubility Solubility in water 70 g/l Freely soluble. Solubility (other) Freely soluble in alcohol and in ether; very soluble in carbontetrachloride; soluble in acetone; slightly soluble in benzene. Initial Boiling Point and Boiling Range 73 Flash Point 51 Evaporation Rate Not available. Flammability (Solid, Gas) Not applicable. Partition Coefficient Partition coef f icient (n-octanol/water) 0.59 Auto-Ignition Temperature 65 Decomposition Temperature Not available. Viscosity Not available. Section 10: Stability and Reactivity Reactivity Not available. Chemical Stability Material is stable under normal conditions. Possibility of Hazardous Reactions No dangerous reaction known under conditions of normal use. Conditions to Avoid None known. Incompatible Materials None known. Hazardous Decomposition Products Irritating and/or toxic f umes or gases. Emits toxic f umes under f ire conditions. Page 3 of 5 Section 11: Toxicological Information Acute Toxicity - LD50 Oral LD50 Mouse 245 mg/kg Rat 320 mg/kg Acute Toxicity - Inhalation No data available Acute Toxicity - Dermal LD50 Guinea pig > 1000 mg/kg Acute Toxicity - Eye No data available Skin Corrosion/Irritation Causes skin irritation. Serious Eye Damage/Irritation Causes serious eye damage. Respiratory or Skin Sensitazation Respiratory sensitization: due to lack of data the classif ication is not possible. Skin sensitization May cause an allergic skin reaction. Skin sensitization Magnussen-Kligman test Result: Positive. Species: Guinea pig Germ Cell Mutagenicity Suspected of causing genetic def ects. Hydroquinone was not mutagenic in S. typhimurium, with or without activation. It induced trif luorothymidine (Tf t) resistance in mouse lymphoma cells, with and without activation. An equivocal response was obtained in tests f or induction of sex-linked recessive lethal mutations in Drosophila. Hydroquinone induced sister-chromatid exchanges (SCE) in CHO cells, with and without activation and chromosomal aberrations with activation, SCEs in human lymphocytes in vitro, and chromosomal aberrations in mammalian erythrocytes. Carcinogenicity IARC IARC: No data available. Carcinogenicity: Suspected of causing cancer. In 2-year studies in mice and rats administered hydroquinone at doses up to 100 and 50 mg/kg, respectively, male rats had an increase in tubular cell adenomas of the kidney, f emale rats showed an increase in mononuclear leukemia, male mice showed no evidence of carcinogenicity, and f emale mice showed an increase in hepatocellular neoplasms (mainly adenomas). Administration of hydroquinone was associated with thyroid f ollicular cell hyperplasia in both male and f emale mice and anisokaryosis, multinucleated hepatocytes, and basophilic f oci of the liver in male mice. Carcinogenicity ACGIH No data available Carcinogenicity NTP No data available Carcinogenicity OSHA No data available Reproductive Toxicity Based on available data, the classif ication criteria are not met. Hydroquinone did not cause birth def ects when given orally to pregnant rats at doses up to 300 mg/kg/day. The frequency of f etal death was increase among rats f ed 2500 mg/kg of hydroquinone. The rate of malf ormations was not signif icantly increased among the of f spring of rabbits administered doses up to 150 mg/kg/day during pregnancy. Specific Target Organ Toxicity - Single Exposure Due to lack of data the classif ication is not possible. Specific Target Organ Toxicity - Repeated Exposure Due to lack of data the classif ication is not possible. Aspiration Hazard Not classif ied. Section 12: Ecological Information Toxicity Very toxic to aquatic lif e. Aquatic Species Test Results Crustacea Fish EC50 LC50 Water f lea (Daphnia magna) Rainbow trout,donaldson trout (Oncorhynchus mykiss) 0.12 - 0.15 mg/l, 48 hours 0.044 mg/l, 96 hours Persistence and Degradability No data is available on the degradability of this product. Bio-accumulative Potential Not available. Mobility in Soil Not available. Other Adverse Effects Not available. Section 13: Disposal Considerations Waste Treatment Methods Product Dispose in accordance with all applicable regulations. Under RCRA, it is the responsibility of the user of the product to determine, at the time of disposal, whether the product meets RCRA criteria f or hazardous waste. Waste Treatment Methods Packaging Dispose of in accordance with local regulations. Empty containers or liners may retain some product residues. This material and its container must be disposed of in a saf e manner (see: Disposal instructions). Empty containers should be taken to an approved waste handling site f or recycling or disposal. Since emptied containers may retain product residue, f ollow label warnings even af ter container is emptied. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number UN3077 UN Proper Shipping Name Environmentally hazardous substances, solid, n.o.s. (Hydroquinone RQ = 100 LBS) Transport Hazard Class(es) 9 Packaging Group III Environmental Hazards Yes Page 4 of 5 Section 15: Regulatory Information US f ederal regulations CERCLA/SARA Reportable Quantities: 100 lb (45.4 kg) All components are on the U.S. EPA TSCA Inventory List. Superf und Amendments and Reauthorization Act of 1986 (SARA) Hazard categories Immediate Hazard - Yes Delayed Hazard - Yes Fire Hazard - No Pressure Hazard - No Reactivity Hazard - No SARA 302 Extremely hazardous substance Chemical name CAS number Reportable Threshold Threshold Threshold quantity planning quantity planning quantity, planning quantity, Hydroquinone 123-31-9 100 lower value 500 lbs upper value 10000 lbs SARA 311/312 Hazardous chemical SARA 313 (TRI reporting) Yes Chemical name CAS number % by wt. Hydroquinone 123-31-9 100 Other f ederal regulations Saf e Drinking Water Act (SDWA) Food and Drug Administration (FDA) Not regulated. Not regulated. US state regulations Calif ornia Saf e Drinking Water and Toxic Enf orcement Act of 1986 (Proposition 65): This material is not known to contain any chemicals currently listed as carcinogens or reproductive toxins. US. Calif ornia Proposition 65 Not Listed. International Inventories: Country(s) or region Inventory name On inventory (yes/no)* Australia Australian Inventory of Chemical Substances (AICS) Canada Domestic Substances List (DSL) Canada Non-Domestic Substances List (NDSL) China Inventory of Existing Chemical Substances in China (IECSC) Europe European Inventory of Existing Commercial Chemical Substances (EINECS) Europe European List of Notif ied Chemical Substances (ELINCS) Japan Inventory of Existing and New Chemical Substances (ENCS) Korea Existing Chemicals List (ECL) New Zealand New Zealand Inventory Philippines Philippine Inventory of Chemicals and Chemical Substances (PICCS) United States & Puerto Rico Toxic Substances Control Act (TSCA) Inventory *A "Yes" indicates that all components of this product comply with the inventory requirements administered by the governing country(s) Yes Yes No Yes Yes No Yes Yes Yes Yes Yes A "No" indicates that one or more components of the product are not listed or exempt from listing on the inventory administered by the governing country(s). Section 16: Other Information Additional Information N/A Prepared By Lisa Russell Revision Date 01/03/2019 15:32 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 5 of 5

Hydroquinone USP 500gm By Letco Medical Item No.Letco685368 NDC No. 62991-1196-03 62991119603 Category: Reagents Reagents UPC No.: 90872010002900
HYDROQUINONE USP 500GM by Letco Medical
Hydroquinone USP 500gm By Letco Medical Item No.Letco685368 NDC No. 62991-1196-03 62991119603 Category: Reagents Reagents UPC No.: 90872010002900

Just change the quantity and save!
Buy more Save More!
Just change the quantity and save!

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

COMPOUNDING ITEMS SPECIALIST
LETCO MEDICAL
COMPOUNDING ITEMS SPECIALIST