FLURBIPROFEN, USP 100GM by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name FLURBIPROFEN USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) [1,1'Biphenyl] -4-acetic acid ,2-f luoro-?-methyl-,(�)-2-(2-f luoro-4- biphenylyl) propionic acid Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Acute toxicity, Oral (Category 3) Signal Word Danger Hazard Statement(s) H301 Toxic if swallowed H315 Causes skin irritation Pictogram(s) Precautionary Statement(s) P264 Wash hands thoroughly af ter handling. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/f ace protection. P302+P312 IF ON SKIN Call a POISON CENTER or doctor/physician if you f eel unwell. P302+P352 IF ON SKIN Wash with soap and water. P305+P351+P338 IF IN EYES Rinse cautiously with water f or several minutes. Remove contact lenses if present and easy to do. continue rinsing. P308+P313 IF exposed or concerned Get medical advice/attention. P332+P313 If skin irritation occurs Get medical advice/attention. P337+P313 If eye irritation persists Get medical advice/attention. P501 Dispose of contents/container to an approved waste disposal plant. Hazards Not Otherwise Classified No inf ormation available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name [1,1'Biphenyl] -4-acetic acid ,2-f luoro-?-methyl-,(�)-2-(2-f luoro-4- biphenylyl) propionic acid Common Name Flurbiprof en CAS Number 5104-49-4 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice Consult a physician. Show this saf ety data sheet to the doctor in attendance. Move out of dangerous area. If Inhaled Remove patient from exposure, keep warm and at rest. If symptoms persist, obtain medical attention. In Case of Skin Contact Remove contaminated clothing immediately and drench af f ected skin with plenty of water, then wash with soap and water. If symptoms persist, obtain medical attention. In Case of Eye Contact If substance has got into the eyes, immediately wash out with plenty of water f or at least 15 minutes. If symptoms persist, obtain medical attention. If Swallowed Do not induce vomiting. Provided the patient is conscious, wash out mouth with water. Obtain immediate medical attention. Most Important Symptoms and Effects May cause allergic skin reaction. Cardiovascular ef f ects. Indication of any immediate medical attention and special treatment needed: In case of accident or if you f eel unwell, seek medical advice immediately (show the label where possible). Page 1 of 4 Section 5: Fire Fighting Measures Suitable Extinguishing Media Water spray, f oam, dry powder or CO2. Special Hazards Arising From the Substance/Mixture No unusual f ire or explosion hazards noted. Special PPE and/or Precautions for Firefighters A self contained breathing apparatus and suitable protective clothing should be worn in f ire conditions. Keep f ire exposed containers cool by spraying with water. Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Eliminate sources of ignition. Avoid contact with skin and eyes. Avoid inhalation of dusts. Wear suitable protective clothing and gloves. Provide adequate ventilation. Methods and Materials Used for Containment Avoid release to the environment. Spillages or uncontrolled discharges into watercourses must be alerted to the Environment Cleanup Procedures Sweep up or vacuum up spillage and collect in suitable container f or disposal. Avoid the generation of dusts during clean-up. Section 7: Handling and Storage Precautions for Safe Handling Eliminate sources of ignition. Provide adequate ventilation. Avoid inhalation of vapours. Avoid contact with skin and eyes. Wear suitable protective clothing.See Section:8. Conditions for Safe Storage Preserve in tight, light resistant containers at controlled temperature between 15o C and 30o C. This material should be handled and stored as per label instructions to ensure product integrity Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters No inf ormation available Appropriate Engineering Controls Provide adequate ventilation, including appropriate local extraction if dusts, f umes or vapours are likely to be evolved. PPE - Eye/Face Protection Goggles giving complete protection to eyes. PPE - Skin Protection Wear suitable gloves and suitable protective clothing. PPE - Body Protection Wear suitable gloves and suitable protective clothing. PPE - Respiratory Protection In case of insuf f icient ventilation or workplace exposure limits are exceeded wear suitable respiratory equipment. Section 9: Physical and Chemical Properties Appearance White crystalline powder Upper/Lower Flammability or Explosive Limits No data available Odor No data available Vapor Pressure No data available Odor Threshold No data available Vapor Density No data available pH No inf ormation available Relative Density No data available Melting Point/Freezing Point Between 114� C and 117� C Solubility Solubility (Water): Practically insoluble. Solubility (Other): Freely soluble in acetone, in dehydrated ethanol, in ether, and in methanol; soluble in acetonitrile. Initial Boiling Point and Boiling Range No data available Flash Point No inf ormation available Evaporation Rate No data available Flammability (Solid, Gas) No data available Partition Coefficient 4.16 Auto-Ignition Temperature No inf ormation available Decomposition Temperature No data available Viscosity No data available Page 2 of 4 Section 10: Stability and Reactivity Reactivity No inf ormation available Chemical Stability Stable under normal conditions. Possibility of Hazardous Reactions No inf ormation available. Conditions to Avoid Avoid friction, sparks, or other means of ignition. Keep away from heat and direct sunlight. Incompatible Materials Strong oxidizing agents. Strong acids. Strong bases Hazardous Decomposition Products May give of f toxic f umes in a f ire condition. Section 11: Toxicological Information Acute Toxicity - LD50 Oral Acute toxicity LD50 Rat Oral 117 mg/kg LD50 Rabbit Dermal 500 mg/kg Acute Toxicity - Inhalation No inf ormation available Acute Toxicity - Dermal Toxic in contact with skin. May cause an allergic skin reaction. Acute Toxicity - Eye May causes eye irritation Skin Corrosion/Irritation Toxic in contact with skin. May cause an allergic skin reaction. Serious Eye Damage/Irritation No inf ormation available. Respiratory or Skin Sensitazation No inf ormation available. Germ Cell Mutagenicity No inf ormation available. Carcinogenicity IARC Due to lack of data the classif ication is not possible. This material is not considered to be a carcinogen by IARC, NTP, or OSHA. Carcinogenicity ACGIH Due to lack of data the classif ication is not possible. This material is not considered to be a carcinogen by IARC, NTP, or OSHA. Carcinogenicity NTP Due to lack of data the classif ication is not possible. This material is not considered to be a carcinogen by IARC, NTP, or OSHA. Carcinogenicity OSHA Due to lack of data the classif ication is not possible. This material is not considered to be a carcinogen by IARC, NTP, or OSHA. Reproductive Toxicity Suspected of damaging f ertility or the unborn child. Specific Target Organ Toxicity - Single Exposure No inf ormation available. Specific Target Organ Toxicity - Repeated Exposure Causes damage to organs (cardiovascular system, gastrointestinal tract) through prolonged or repeated exposure. Aspiration Hazard No inf ormation available. Section 12: Ecological Information Toxicity No inf ormation available. Persistence and Degradability No inf ormation available. Bio-accumulative Potential No inf ormation available. Mobility in Soil No inf ormation available. Other Adverse Effects No inf ormation available. Section 13: Disposal Considerations Waste Treatment Methods Product Do not empty into drains, dispose of this material and its container at hazardous or special waste collection point. To be disposed of as hazardous waste. Disposal should be in accordance with local, state or national legislation. Waste Treatment Methods Packaging No f urther data available. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number 2811 UN Proper Shipping Name Toxic solids, organic, n.o.s. (Flurbiprof en) Transport Hazard Class(es) 6.1 Packaging Group III Environmental Hazards No data available Page 3 of 4 Section 15: Regulatory Information Saf ety, health and environmental regulations/legislation specif ic f or the substance or mixture substance or mixture This Saf ety Data Sheet was prepared in According to GHS Classif ication in accordance with 29 CFR 1910 (OSHA HCS). Chemical Saf ety Assessment No inf ormation available. Superf und Amendments and Reauthorization Act of 1986 (SARA) Hazard categories: Immediate Hazard � Yes Delayed Hazard � Yes Fire Hazard � No Pressure Hazard � No Reactivity Hazard - No Section 16: Other Information Additional Information N/A Prepared By Lisa Russell Revision Date 01/11/2019 16:21 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
