BENZOCAINE, USP 500GM by Letco Medical Safety Data Sheet Section 1: Identification Common Name/Trade Name BENZOCAINE USP Supplier Information Letco Medical, LLC 1316 Commerce Drive NW Decatur, AL 35601 1 (800) 239-5288 +1 (734) 843-4693 IN CASE OF EMERGENCY: Chemtrec 1 (800) 424-9300 (24 hours) Product Synonym(s) Benzoic acid, p-amino- ethyl ester; Benzocaine; 4-Aminobenzoic acid ethyl ester Relevant Use(s) of Product Manuf acture or Compounding of Substances Section 2: Hazards Identification Classification of Substance or Mixture Acute Toxicity, Dermal (Category 5), Acute Toxicity, Oral (Category 5), Acute Toxicity, Inhalation (Category 5), Skin Irritation (Category 2), Eye Irritation (Category 2A), Sensitization, Skin (Category 1) Signal Word Warning Hazard Statement(s) H303 May be harmf ul if swallowed H313 May be harmf ul in contact with skin H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H333 May be harmf ul if inhaled Pictogram(s) Precautionary Statement(s) P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/f ace protection. P305+P351+P338 IF IN EYES Rinse cautiously with water f or several minutes. Remove contact lenses if present and easy to do. continue rinsing. Hazards Not Otherwise Classified No data available Ingredient(s) with Unknown Toxicity No data available Section 3: Composition/Information on Ingredients Chemical Name Ethyl 4-aminobenzoate Common Name Benzocaine CAS Number 94-09-7 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice General considerations : The substance is harmf ul and irritant. If Inhaled Remove from exposure and move to fresh air immediately. If not breathing, give artif icial respiration. If breathing is dif f icult, give oxygen. Get medical aid. In Case of Skin Contact Get medical aid. Flush skin with plenty of water f or at least 15 minutes while removing contaminated clothing and shoes. Wash clothing bef ore reuse. In Case of Eye Contact Immediately f lush eyes with plenty of water f or at least 15 minutes, occasionally lif ting the upper and lower eyelids. Get medical aid. If Swallowed Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupf uls of milk or water. Most Important Symptoms and Effects Inhalation : Causes respiratory tract irritation. May be harmf ul if inhaled. Skin : Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be harmf ul if absorbed through the skin. Eyes : Causes eye irritation. May cause chemical conjunctivitis. Ingestion : May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmf ul if swallowed Page 1 of 4 Section 5: Fire Fighting Measures Suitable Extinguishing Media Use water spray, alcohol-resistant f oam, dry chemical or carbon dioxide. Special Hazards Arising From the Substance/Mixture Emits toxic and corrosive f umes of CO, CO2 & Nox. Special PPE and/or Precautions for Firefighters Wear NIOSH/MSHA approved or equivalent self contained breathing apparatus with f ull f ace respirator and f ull protective clothing. Section 6: Accidental Release Measures Personal Precautions, Protective Equipment and Emergency Procedures Wear appropriate NIOSH/MSHA approved respirator, chemical saf ety goggles, compatible chemical resistant gloves, saf ety boots. Saf ety shower, eye bath and mechanical exhaust required. Avoid dust f ormation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Avoid breathing dust. Methods and Materials Used for Containment Prevent f urther leakage or spillage if saf e to do so. Do not let product enter drains. Discharge into the environment must be avoided Cleanup Procedures Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers f or disposal. Section 7: Handling and Storage Precautions for Safe Handling Wash thoroughly af ter handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust. Avoid contact with eyes, skin, and clothing. Avoid inhalation and ingestion. Use with adequate ventilation. Wash clothing bef ore reuse. Conditions for Safe Storage Preserve in well-closed containers(USP 38). Protected from light(BP2015, EP 8.6). Keep away from incompatible substances. Avoid contact with oxidizing agents. Section 8: Exposure Controls/Personal Protection Components with Workplace Control Parameters Exposure Limits : No data available Appropriate Engineering Controls Facilities storing or utilizing this material should be equipped with an eyewash f acility and a saf ety shower. Use adequate ventilation to keep airborne concentrations low PPE - Eye/Face Protection Wear chemical saf ety goggles. PPE - Skin Protection Protective clothing should give complete coverage to avoid skin contact. PPE - Body Protection Wear appropriate protective gloves. Protective clothing should give complete coverage to avoid skin contact. PPE - Respiratory Protection Wear appropriate NIOSH/MSHA approved respirator. Section 9: Physical and Chemical Properties Appearance Small white crystals or white, crystalline powder. Upper/Lower Flammability or Explosive Limits Non-f lammable, May be combustible at high temperature. Odor Odorless Vapor Pressure 0.0006 (250C) -lit. Odor Threshold No data available Vapor Density No data available pH pH (Sat. aq soln.) : 6.0- 7.0 Relative Density No data available Melting Point/Freezing Point 88-92�C (End of melting does not exceed 2�C) Solubility Water solubility : Very slightly soluble in water. Freely soluble in alcohol in chlorof orm and in ether. Sparingly soluble in almond oil and olive oil. Dissolves in dilute acids. Initial Boiling Point and Boiling Range 172�C @ 17.00hPA -lit. Flash Point >100 �C-lit. Evaporation Rate No data available Flammability (Solid, Gas) Non-f lammable, May be combustible at high temperature. Partition Coefficient 2.49 -lit. Auto-Ignition Temperature >450 deg C. -lit. Decomposition Temperature No data available Viscosity No data available Page 2 of 4 Section 10: Stability and Reactivity Reactivity Reacts with strong oxidizing agents, reducing agents, acids, bases. Chemical Stability Stable under normal temperatures and pressures. Light and air sensitive. Possibility of Hazardous Reactions None under normal processing. Conditions to Avoid Incompatible materials, dust generation, excess heat, ignition sources, strong oxidants. Incompatible Materials Strong oxidizing agents, reducing agents, acids, bases. Hazardous Decomposition Products Toxic and corrosive f umes or Nitrogen oxides, carbon monoxide, carbon dioxide. Section 11: Toxicological Information Acute Toxicity - LD50 Oral LD50 Oral - rat - 3042 mg/kg Acute Toxicity - Inhalation Causes respiratory tract irritation. May be harmf ul if inhaled. Acute Toxicity - Dermal Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be harmf ul if absorbed through the skin. Acute Toxicity - Eye Causes eye irritation. May cause chemical conjunctivitis. Skin Corrosion/Irritation No data available Serious Eye Damage/Irritation Causes eye irritation. May cause chemical conjunctivitis. Respiratory or Skin Sensitazation Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be harmf ul if absorbed through the skin. Germ Cell Mutagenicity No data available Carcinogenicity IARC No data available Carcinogenicity ACGIH No data available Carcinogenicity NTP No data available. Carcinogenicity OSHA No data available. Reproductive Toxicity No data available Specific Target Organ Toxicity - Single Exposure No data available Specific Target Organ Toxicity - Repeated Exposure No data available Aspiration Hazard No data available Section 12: Ecological Information Toxicity Toxicity to f ish LC50 - Oncorhynchus mykiss (rainbow trout) - 7,2 mg/l - 96 h. Component Freshwater Algae Freshwater Fish Microtox Water Flea Benzocaine Not listed 7.48 - 11.3 mg/L LC50 96 h 24.9 - 26.9 mg/L LC50 96 h 34.6 - 36.1 mg/L LC50 96 h 5.92 - 9.76 mg/L LC50 96 h 17.9 - 20.1 mg/L LC50 96 h Not listed Not listed Persistence and Degradability Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The products of degradation are more toxic. Bio-accumulative Potential No data available Mobility in Soil log Pow : 1.92 Other Adverse Effects No data available Section 13: Disposal Considerations Waste Treatment Methods Product Observe all f ederal, state, and local environmental regulations. Waste Treatment Methods Packaging Dispose of as unused product. Special Precautions Landfill or Incinerations No data available Other Information No data available Section 14: Transport Information UN Number Not dangerous goods UN Proper Shipping Name N/A Transport Hazard Class(es) N/A Packaging Group N/A Environmental Hazards N/A Page 3 of 4 Section 15: Regulatory Information Substance giving rise to classif ication : Benzocaine CAS Number : 94-09-7 EC (EINECS) No. : 202-303-5 15.1 Other National Regulatory Inf ormation U.S. TSCA listings : Listed on the TSCA Inventory. DOT classif ication : Not regulated as a hazardous substances. OSHA, CERCLA SARA TITLE III : None of the chemicals in this product are considered highly hazardous by OSHA. Other Inf ormation : Listed on the Canadian DSL. Section 16: Other Information Additional Information U.S. HMIS Ratings : Health: 2; Flammability: 1; Reactivity: 0; Personal Protection: E Prepared By Lisa Russell Revision Date 01/15/2019 14:30 Disclaimer Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage resulting from handling, storage, use or from contact with the above product. Page 4 of 4
