ACETAZOLAMIDE, USP 100GM by Letco Medical Safety Data Sheet
Section 1: Identification
Common Name/Trade Name ACETAZOLAMIDE USP
Supplier Information
Letco Medical, LLC
1316 Commerce Drive NW
Decatur, AL 35601
1 (800) 239-5288
+1 (734) 843-4693
IN CASE OF EMERGENCY:
Chemtrec
1 (800) 424-9300 (24 hours)
Product Synonym(s) N-(5-Sulf amoyl-1,3,4-thiadiazol-2-yl)acetamide, N-(5-[Aminosulf onyl]-1,3,4-thiadiazol-2-yl)acetamide, 5-Acetamido1,3,4-thiadiazole-2-sulf onamide
Relevant Use(s) of Product Manuf acture or Compounding of Substances
Section 2: Hazards Identification
Classification of Substance
or Mixture Skin irritation (Category 2), Eye irritation (Category 2)
Signal Word Warning
Hazard Statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
Pictogram(s)
Precautionary Statement(s) P305+P351+P338
IF IN EYES Rinse cautiously with water f or several minutes. Remove contact lenses if
present and easy to do. continue rinsing.
Hazards Not Otherwise
Classified None
Ingredient(s) with Unknown
Toxicity
No data Available
Section 3: Composition/Information on Ingredients
Chemical Name Acetazolamide
Common Name Acetazolamide
CAS Number 59-66-5
Impurities and/or Stabilizing
Additives No data available
Section 4: First Aid Measures
General Advice
In case of reactions described in hazards identif ication or other severe immediate or persisting symptoms, seek medical advice and call the nearest poison center. Show the label and this saf ety data sheet.
If Inhaled Assure fresh air breathing. Rest. If you f eel unwell, seek medical advice.
In Case of Skin Contact Remove af f ected clothing and wash all exposed skin area with mild soap and water, f ollowed by warm water rinse.
In Case of Eye Contact Rinse immediately with plenty of water. Obtain medical attention if pain, blinking, tears or redness persist.
If Swallowed Rinse mouth. If swallowed, seek medical advice immediately and show this container or label.
Most Important Symptoms
and Effects No data available
Section 5: Fire Fighting Measures
Suitable Extinguishing
Media
Water spray. Carbon dioxide. Dry powder. Do not use a heavy water stream. Use water spray or f og f or cooling
exposed containers. Do not enter f ire area without proper protective equipment, including respiratory protection.
Special Hazards Arising
From the
Substance/Mixture
Incomplete combustion will generate poisonous carbon monoxide, carbon dioxide and other toxic gases.
Special PPE and/or
Precautions for Firefighters Wear proper protective equipment, including respiratory protection.
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Section 6: Accidental Release Measures
Personal Precautions,
Protective Equipment and
Emergency Procedures
Spill should be handled by trained cleaning personnel properly equipped with respiratory and eye protection.
Methods and Materials
Used for Containment Remove ignition sources. Evacuate area. Avoid dust production. Ensure adequate ventilation.
Cleanup Procedures
To clean the f loor and all objects contaminated by this material, use: Water/Detergent. Avoid dust production. Ensure
adequate ventilation.
Section 7: Handling and Storage
Precautions for Safe
Handling
Avoid contact with skin and eyes. Avoid f ormation of dust and aerosols. Avoid all unnecessary exposure. Ensure
prompt removal from eyes, skin and clothing. Material should be handled in a laboratory hood whenever possible.
Handle in accordance with good industrial hygiene and saf ety procedurs.
Conditions for Safe Storage Store at room temperature. Keep container tightly closed in a dry and well-ventilated place. Store away from all heat
sources, including direct sunlight. Open f lame. Sources of ignition. Sparks. Incompatible materials.
Section 8: Exposure Controls/Personal Protection
Components with
Workplace Control
Parameters
No data available
Appropriate Engineering
Controls Provide local exhaust or general room ventilation.
PPE - Eye/Face Protection Chemical goggles or saf ety glasses.
PPE - Skin Protection Wear suitable gloves resistant to chemical penetration. Wear suitable protective clothing.
PPE - Body Protection Wear suitable gloves resistant to chemical penetration. Wear suitable protective clothing.
PPE - Respiratory
Protection Wear approved mask. (P1) In case of insuf f icient ventilation, wear suitable respiratory equipment.
Section 9: Physical and Chemical Properties
Appearance Powder, White.
Upper/Lower Flammability
or Explosive Limits No data available
Odor No data available
Vapor Pressure No data available
Odor Threshold No data available
Vapor Density No data available
pH 4-6
Relative Density No data available
Melting Point/Freezing
Point
258 - 259 �C
Solubility
Sparingly soluble in cold water, slightly soluble in alcohol, acetone; practically insoluble in chlorof orm, carbon
tetrachloride and ether. It dissolves in dilute alkali.
Initial Boiling Point and
Boiling Range No data available
Flash Point No data available
Evaporation Rate No data available
Flammability (Solid, Gas) No data available
Partition Coefficient No data available
Auto-Ignition Temperature No data available
Decomposition
Temperature No data available
Viscosity No data available
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Section 10: Stability and Reactivity
Reactivity No data available
Chemical Stability Stable under normal conditions.
Possibility of Hazardous
Reactions None under normal conditions.
Conditions to Avoid None known.
Incompatible Materials Strong oxidizers.
Hazardous Decomposition
Products Hazardous polymerization will not occur.
Section 11: Toxicological Information
Acute Toxicity - LD50 Oral LD50 Oral - mouse - 4,300 mg/kg (Acetazolamide)
Acute Toxicity - Inhalation No data available
Acute Toxicity - Dermal No data available
Acute Toxicity - Eye No data available
Skin Corrosion/Irritation No data available
Serious Eye
Damage/Irritation No data available
Respiratory or Skin
Sensitazation No data available
Germ Cell Mutagenicity No data available
Carcinogenicity IARC No data available
Carcinogenicity ACGIH No data available
Carcinogenicity NTP No data available.
Carcinogenicity OSHA No data available
Reproductive Toxicity No data available
Specific Target Organ
Toxicity - Single Exposure No data available
Specific Target Organ
Toxicity - Repeated
Exposure
No data available
Aspiration Hazard No data available
Section 12: Ecological Information
Toxicity No data available
Persistence and
Degradability
No data available
Bio-accumulative Potential No data available
Mobility in Soil No data available
Other Adverse Effects No data available
Section 13: Disposal Considerations
Waste Treatment Methods
Product
Dispose of this material and its container at hazardous or special waste collection point. Dispose in a saf e manner in
accordance with local/national regulations.
Waste Treatment Methods
Packaging
No data available
Special Precautions Landfill
or Incinerations No data available
Other Information No data available
Section 14: Transport Information
UN Number Not dangerous goods.
UN Proper Shipping Name N/A
Transport Hazard Class(es) N/A
Packaging Group N/A
Environmental Hazards N/A
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Section 15: Regulatory Information
This saf ety data sheet complies with the requirements of Globally Harmonized System of Classif ication and Labeling of Chemicals
Section 16: Other Information
Additional Information N/A
Prepared By Lisa Russell
Revision Date 01/15/2019 15:21
Disclaimer
Letco Medical, LLC believes that the above information is correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is
based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. If the product is used as a component in another
product, this information may not be applicable. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE, WARRANTY OF MERCHANTABILITY OR ANY OTHER
WARRANTY, EXPRESSED OR IMPLIED, IS MADE CONCERNING THE INFORMATION PROVIDED ABOVE. Letco Medical shall not be held liable for any loss or damage
resulting from handling, storage, use or from contact with the above product.
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