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Rx Item-BRAFTOVI 75MG (13500 MG) CAPSULES 1X180 EA

Item No.:RX70255-0025-01  Generic Name:<br>ENCORAFENIB<br> Description:<br>BRAFTOVI, 75MG, (13500 MG), CAPSULES, 1X180 EA<br> Alt Item #: <br>5436704<br> NDC:<br>70255-0025-01<br> UPC:<br>370255-02501 Generic Name:
ENCORAFENIB

 Description:
BRAFTOVI, 75MG, (13500 MG), CAPSULES, 1X180 EA
 Alt Item #: 
5436704

 NDC:
70255-0025-01

 UPC:
370255-025012
 Contract:

Contract Alias:

Strength:
75MG

 FOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-BRAFTOVI 75MG (13500 MG) CAPSULES 1X180 EA

$0.00

Item No.:RX70255-0025-01 Generic Name:
ENCORAFENIB
Description:
BRAFTOVI, 75MG, (13500 MG), CAPSULES, 1X180 EA
Alt Item #:
5436704
NDC:
70255-0025-01
UPC:
370255-025012
Contract:
Contract Alias:
Strength:
75MG
Form:
CAPSULES
Size:
1X180 EA Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in sco

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hese highlights do not include all the information needed to use BRAFTOVI safely and effectively. See full prescribing information for BRAFTOVI. BRAFTOVI� (encorafenib) capsules, for oral use Initial U.S. Approval: 2018 INDICATIONS AND USAGE BRAFTOVI is a kinase inhibitor indicated, in combination with binimetinib, for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test. (1, 2.1) Limitations of Use: BRAFTOVI is not indicated for treatment of patients with wild-type BRAF melanoma. (1, 5.2) DOSAGE AND ADMINISTRATION Confirm the presence of BRAF V600E or V600K mutation in tumor specimens prior to the initiation of BRAFTOVI. (2.1) The recommended dose is 450 mg orally once daily in combination with binimetinib. Take BRAFTOVI with or without food. (2.2) DOSAGE FORMS AND STRENGTHS Capsules: 50 mg and 75 mg. (3) CONTRAINDICATIONS None. (4) WARNINGS AND PRECAUTIONS New Primary Malignancies, cutaneous and non-cutaneous: Can occur. Monitor for malignancies and perform dermatologic evaluations prior to, while on therapy, and following discontinuation of treatment. (5.1) Tumor Promotion in BRAF Wild-Type Tumors: Increased cell proliferation can occur with BRAF inhibitors. (5.2) Hemorrhage: Major hemorrhagic events can occur. (5.3) Uveitis: Perform ophthalmologic evaluation at regular intervals and for any visual disturbances. (5.4) QT Prolongation: Monitor electrolytes before and during treatment. Correct electrolyte abnormalities and control for cardiac risk factors for QT prolongation. Withhold BRAFTOVI for QTc of 500 ms or greater. (5.5) Embryo-Fetal Toxicity: Can cause fetal harm. Advise females with reproductive potential of potential risk to the fetus and to use effective non-hormonal method of contraception. (5.6, 8.1, 8.3) ADVERSE REACTIONS Most common adverse reactions (?25%) for BRAFTOVI, in combination with binimetinib, are fatigue, nausea, vomiting, abdominal pain, and arthralgia. (6.1) To report SUSPECTED ADVERSE REACTIONS, contact Array BioPharma at 1-844-792-7729 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. DRUG INTERACTIONS Strong or moderate CYP3A4 inhibitors: Concomitant use may increase encorafenib plasma concentration. If concomitant use cannot be avoided, modify BRAFTOVI dose. (2.4, 7.1) Strong or moderate CYP3A4 inducers: Concomitant use may decrease encorafenib plasma concentrations. Avoid concomitant use. (7.1) Sensitive CYP3A4 substrates: Concomitant use with BRAFTOVI may increase toxicity or decrease efficacy of these agents. Avoid hormonal contraceptives. (7.2) USE IN SPECIFIC POPULATIONS Lactation: Advise not to breastfeed. (8.2) Males of Reproductive Potential: BRAFTOVI may impair fertility. (8.3) See 17 for PATIENT COUNSELING INFORMATION and Medication Guide. Revised: 6/2018

Item No.:RX70255-0025-01  Generic Name:<br>ENCORAFENIB<br> Description:<br>BRAFTOVI, 75MG, (13500 MG), CAPSULES, 1X180 EA<br> Alt Item #: <br>5436704<br> NDC:<br>70255-0025-01<br> UPC:<br>370255-02501
BRAFTOVI 75MG (13500 MG) CAPSULES 1X180
Item No.:RX70255-0025-01 Generic Name:
ENCORAFENIB
Description:
BRAFTOVI, 75MG, (13500 MG), CAPSULES, 1X180 EA
Alt Item #:
5436704
NDC:
70255-0025-01
UPC:
370255-02501

 Generic Name:
ENCORAFENIB

 Description:
BRAFTOVI, 75MG, (13500 MG), CAPSULES, 1X180 EA
 Alt Item #: 
5436704

 NDC:
70255-0025-01

 UPC:
370255-025012
 Contract:

Contract Alias:

Strength:
75MG

 F
Array BioPharma Inc
Generic Name: ENCORAFENIB Description: BRAFTOVI, 75MG, (13500 MG), CAPSULES, 1X180 EA Alt Item #: 5436704 NDC: 70255-0025-01 UPC: 370255-025012 Contract: Contract Alias: Strength: 75MG F

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
American Pharma Wholesale
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.