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Cephalexin 500mg Cap 500 by Aurobindo Pharma eXP 2/19

NDC 65862-0019-05 UPC/GTIN No.3-65862-01905-9 Mfg.Part No.1905Aurobindo Pharma USAThis Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).Aurobindo Pharma USAImage 4 of Cephalexin 500mg Cap 500 by Aurobindo Pharma eXP 2/19

Cephalexin 500mg Cap 500 by Aurobindo Pharma eXP 2/19

$605.00$549.00

NDC No. 65862-0019-05 UPC/GTIN No. 3-65862-01905-9 MPN 1905 Only Physician,Pharmacy or Licensed Facility can order this Rx Item No. Rx606259 Cephalexin 500mg Cap 500 by Aurobindo Pharma Item No. 3606259 NDC No. 65862001905 UPC No. 365862019059 Other Name Keflex,Panixine,Biocef,Zartan Therapeutic Code 081206 Therapeutic Class Second Generation Cephalosporins Item Class Non Controlled Rx. Case Qnty: 12 Therapeutic Code 081206 Second Generation Cephalosporins Info Cephalosporin Antibacterial [Epc],

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CEPHALEXIN - cephalexin capsule
Sun Pharmaceutical Industries Limited


DESCRIPTION

Cephalexin Capsules, USP is a semisynthetic cephalosporin antibiotic intended for oral administration. It is 7-(D-a-Amino-a-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid monohydrate. Cephalexin has the molecular formula C16 H17 N3 O4 S•H2 O and the molecular weight is 365.41.
The nucleus of cephalexin is related to that of other cephalosporin antibiotics. The compound is a zwitterion; ie, the molecule contains both a basic and an acidic group. The isoelectric point of cephalexin in water is approximately 4.5 to 5.

The crystalline form of cephalexin which is available is a monohydrate. It is a white crystalline solid having a bitter taste. Solubility in water is low at room temperature; 1 or 2 mg/mL may be dissolved readily, but higher concentrations are obtained with increasing difficulty.

The cephalosporins differ from penicillins in the structure of the bicyclic ring system. Cephalexin has a D -phenylglycyl group as substituent at the 7-amino position and an unsubstituted methyl group at the 3-position.

Each capsule contains cephalexin monohydrate equivalent to 250 mg (720 ?mol) or 500 mg (1,439 ?mol) of cephalexin. The capsules also contain colloidal silicon dioxide, D & C Yellow No. 10, FD & C Blue No. 2, gelatin, magnesium stearate, sodium starch glycolate, and titanium dioxide.

CLINICAL PHARMACOLOGY

Human Pharmacology
Cephalexin is acid stable and may be given without regard to meals. It is rapidly absorbed after oral administration. Following doses of 250 mg, 500 mg, and 1 g, average peak serum levels of approximately 9, 18, and 32 mcg/mL respectively were obtained at 1 hour. Measurable levels were present 6 hours after administration. Cephalexin is excreted in the urine by glomerular filtration and tubular secretion. Studies showed that over 90% of the drug was excreted unchanged in the urine within 8 hours. During this period, peak urine concentrations following the 250-mg, 500-mg, and 1-g doses were approximately 1,000, 2,200, and 5,000 mcg/mL respectively.

Microbiology
In vitro tests demonstrate that the cephalosporins are bactericidal because of their inhibition of cell-wall synthesis. Cephalexin has been shown to be active against most strains of the following microorganisms both in vitro and in clinical infections as described in the INDICATIONS AND USAGE section.

Aerobes, Gram-positive:

Staphylococcus aureus (including penicillinase-producing strains)
Streptococcus pneumoniae (penicillin-susceptible strains)
Streptococcus pyogenes
Aerobes, Gram-negative:

Escherichia coli
Haemophilus influenzae
Klebsiella pneumoniae
Moraxella (Branhamella) catarrhalis
Proteus mirabilis
Note –Methicillin-resistant staphylococci and most strains of enterococci (Enterococcus faecalis [formerly Streptococcus faecalis ]) are resistant to cephalosporins, including cephalexin. It is not active against most strains of Enterobacter spp., Morganella morganii , and Proteus vulgaris. It has no activity against Pseudomonas spp. or Acinetobacter calcoaceticus. Penicillin-resistant Streptococcus pneumoniae is usually cross-resistant to beta-lactam antibiotics.

NDC 65862-0019-05 UPC/GTIN No.3-65862-01905-9 Mfg.Part No.1905
Cephalexin 500mg Cap 500 by Aurobindo Ph
NDC 65862-0019-05 UPC/GTIN No.3-65862-01905-9 Mfg.Part No.1905

Aurobindo Pharma USA
Aurobindo Pharma USA

This Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).
Click above for Keflex
This Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).

Aurobindo Pharma USA
Aurobindo Pharma USA

Image 4 of Cephalexin 500mg Cap 500 by Aurobindo Pharma eXP 2/19