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Rx Item-Ondansetron 2Mg/Ml Vial 25X2Ml Ml By Apotex Pharma Gen Zofran

Item No.:RX551424 NDC No.60505613005 UPC No.:360505613052 NDC No.60505-6130-05 60505-6130-5 UPC/GTIN No.3-60505-61305-2 MPN 13005Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopBRAND: ONDANSETRON NDC: 60505-6130-05,60505613005 UPC: 3-60505-61305-2,360505613052 Claris Lifesciences IncWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.ONDANSETRON INJ 2MG/ML CLARISNDC 36000-0013-01 UPC/GTIN No.3-36000-01301-7 Mfg.Part No.1301

Rx Item-Ondansetron 2Mg/Ml Vial 25X2Ml Ml By Apotex Pharma Gen Zofran

$18.00$13.99

Item No.:RX551424 NDC No.60505613005 UPC No.:360505613052 NDC No.60505-6130-05 60505-6130-5 UPC/GTIN No.3-60505-61305-2 MPN 13005 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No.Rx551424 Ondansetron 2mg/ml Vial 25x2ml ml by Apotex Pharma Item No.551424 NDC No.60505613005 6050561305 UPC No.360505-613

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Clinical Information
Gen. Code and Des.
61716 ondansetron HCl/PF INJECTION VIAL 4 MG/2 ML
GCN and Des.
97502 ondansetron HCl/PF INJECTION VIAL 4 MG/2 ML
Strength
4MG-2ML
Dose Form
VIAL (ML)
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
56222000 5-HT3 RECEPTOR ANTAGONISTS
Active Ingredients
3568 ondansetron HCl 103639049
9870 preservative free
Inactive Ingredients
2332 sodium citrate 68042



ZOFRAN- ondansetron hydrochloride solution
ZOFRAN ODT- ondansetron tablet, orally disintegrating
ZOFRAN- ondansetron hydrochloride tablet, film coated
GlaxoSmithKline LLC


1 INDICATIONS AND USAGE
ZOFRAN� is indicated for the prevention of nausea and vomiting associated with:

highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2.

initial and repeat courses of moderately emetogenic cancer chemotherapy.

radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen.
ZOFRAN is also indicated for the prevention of postoperative nausea and/or vomiting.
2 DOSAGE AND ADMINISTRATION
2.1 Dosage
The recommended dosage regimens for adult and pediatric patients are described in Table 1 and Table 2, respectively.
Corresponding doses of ZOFRAN tablets, ZOFRAN ODT� orally disintegrating tablets and ZOFRAN oral solution may be used interchangeably.
DOSAGE FORMS AND STRENGTHS
ZOFRAN tablets are oval, film-coated tablets engraved with "Zofran" on one side and are available in the following strengths:

4 mg � white tablet with "4" engraved on the other side.

8 mg � yellow tablet with "8" engraved on the other side.
ZOFRAN ODT orally disintegrating tablets are white, round, and plano-convex tablets available in the following strengths:

4 mg � debossed with "Z4" on one side.

8 mg � debossed with "Z8" on one side.
ZOFRAN oral solution, 4 mg/5 mL, is a clear, colorless to light yellow liquid with a characteristic strawberry odor available in a 50-mL bottle.
4 CONTRAINDICATIONS
ZOFRAN is contraindicated in patients:
1.
known to have hypersensitivity (e.g., anaphylaxis) to ondansetron or any of the components of the formulation [see Adverse Reactions (6.2)].
2.
receiving concomitant apomorphine due to the risk of profound hypotension and loss of consciousness.
DESCRIPTION
The active ingredient in ZOFRAN tablets and ZOFRAN oral solution is ondansetron hydrochloride as the dihydrate, the racemic form of ondansetron and a selective blocking agent of the serotonin 5?HT3receptor type. Chemically it is (�) 1, 2, 3, 9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate
Mechanism of Action
Ondansetron is a selective 5?HT3 receptor antagonist. While its mechanism of action has not been fully characterized, ondansetron is not a dopamine?receptor antagonist. Serotonin receptors of the 5?HT3 type are present both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone of the area postrema. It is not certain whether ondansetron's antiemetic action is mediated centrally, peripherally, or in both sites. However, cytotoxic chemotherapy appears to be associated with release of serotonin from the enterochromaffin cells of the small intestine. In humans, urinary 5?hydroxyindoleacetic acid (5?HIAA) excretion increases after cisplatin administration in parallel with the onset of emesis. The released serotonin may stimulate the vagal afferents through the 5?HT3 receptors and initiate the vomiting reflex.


Item No.:RX551424 NDC No.60505613005 UPC No.:360505613052 NDC No.60505-6130-05 60505-6130-5 UPC/GTIN No.3-60505-61305-2 MPN 13005
Ondansetron 2Mg/Ml Vial 25X2Ml
Item No.:RX551424 NDC No.60505613005 UPC No.:360505613052 NDC No.60505-6130-05 60505-6130-5 UPC/GTIN No.3-60505-61305-2 MPN 13005

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
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Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

BRAND: ONDANSETRON NDC: 60505-6130-05,60505613005 UPC: 3-60505-61305-2,360505613052 Claris Lifesciences Inc
Ondansetron 2Mg/Ml Vial 25X2Ml Ml By Apo
BRAND: ONDANSETRON NDC: 60505-6130-05,60505613005 UPC: 3-60505-61305-2,360505613052 Claris Lifesciences Inc

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

ONDANSETRON INJ 2MG/ML CLARIS
36000-0013-01
ONDANSETRON INJ 2MG/ML CLARIS

NDC 36000-0013-01 UPC/GTIN No.3-36000-01301-7 Mfg.Part No.1301
RX ITEM-Ondansetron 2Mg/Ml Vial 25X2Ml M
NDC 36000-0013-01 UPC/GTIN No.3-36000-01301-7 Mfg.Part No.1301