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Albon (Sulfadimethoxine) 500mg 500 Tablets By Zoetis

Albon Tabs 500mg B500 by Zoetis MFR
Zoetis Animal Health
SKU
033189
Unit
B500
MFR Code
10000294
Vendor SKUs
10000294
Case Qty
12
Rx
Yes
Size
B500
Form
tablet
Strength
500 mg
Brand
AmericanPharmaWholesale.com MFR
Zoetis Animal Health
SKU
033189
Unit
B500
MFR Code
10000294
Vendor SKUs
10000294
Case Qty
12
Rx
Yes
Size
B500
Form
tablet
Strength
500 mg
Brand
AlbWe offer OTC, Rx, Medical Supplies and More.  Retail@wholesale MFR
Zoetis Animal Health
SKU
033189
Unit
B500
MFR Code
10000294
Vendor SKUs
10000294
Case Qty
12
Rx
Yes
Size
B500
Form
tVet Rx Item Can Only Be Orderred By A Veterinarian Or Facility Staffed With. This Rx Item Can Only Be Used In Established Veterianarian/Client/Patient Relationships. Non Vet But Rx Item Can Only Be Or

Albon (Sulfadimethoxine) 500mg 500 Tablets By Zoetis

$489.99$385.61

VET-RX-MW033189 033189 Vet Rx Item Can Only Be Ordered By A Veterinarian Or Facility Staffed With. This Rx Item Can Only Be Used In Established Veterinarian/Client/Patient Relationships. Non Vet But Rx Item Can Only Be Ordered By Physicians, Pharmacies Or Facilities Properly Licensed To Order This Item. Albon Tabs 500mg B500 By Zoetis Item No.:Vet-Rx-MW 00033189

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Albon Tabs 500mg: MFR
Zoetis Animal Health
SKU
033189
Unit
B500
MFR Code
10000294
Vendor SKUs
10000294
Case Qty
12
Rx
Yes
Size
B500
Form
tablet
Strength
500 mg
Brand
Albon
Species
canine | feline

Albon Tablets are indicated for the treatment of respiratory, genitourinary tract, enteric, and soft tissue infections in dogs and cats: tonsillitis, cystitis, pustular dermatitis, bacterial enteritis, pharyngitis, nephritis, anal gland infections, canine salmonellosis, bronchitis, metritis, abscesses, bacterial enteritis associated with coccidiosis in dogs, pneumonia, pyometra and wound infections when caused by streptococci, staphylococci, escherichia, salmonella, klebsiella, proteus or shigella organisms sensitive to sulfadimethoxine.

ALBON�

Zoetis
(sulfadimethoxine)
Tablets
For the treatment of sulfadimethoxine-sensitive bacterial infections in dogs and cats and bacterial enteritis associated with coccidiosis in dogs.
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
DESCRIPTION: Albon is a low-dosage, rapidly absorbed, long-acting sulfonamide, effective for the treatment of a wide range of bacterial infections commonly encountered in dogs and cats.
Sulfadimethoxine is a white, almost tasteless and odorless compound. Chemically, it is N1-(2,6-dimethoxy-4-pyrimidinyl) sulfanilamide. The structural formula is:

Action: Sulfadimethoxine has been demonstrated clinically or in the laboratory to be effective against a variety of organisms, such as streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.1,2 These organisms have been demonstrated in respiratory, genitourinary, enteric, and soft tissue infections of dogs and cats.
The systemic sulfonamides which include sulfadimethoxine are bacteriostatic agents. Sulfonamides competitively inhibit bacterial synthesis of folic acid (pterolyglutamic acid) from para-aminobenzoic acid. Mammalian cells are capable of utilizing folic acid in the presence of sulfonamides.
The tissue distribution of sulfadimethoxine, as with all sulfonamides, is a function of plasma levels, degree of plasma protein binding, and subsequent passive distribution in the tissues of the lipid-soluble un-ionized form. The relative amounts are determined by both its pKa and by the pH of each tissue. Therefore, levels tend to be higher in less acid tissue and body fluids or those diseased tissues having high concentrations of leucocytes.2
In the dog, sulfadimethoxine is not acetylated as in most other animals, and it is excreted predominantly as the unchanged drug.3 Sulfadimethoxine has a relatively high solubility at the pH normally occurring in the kidney, precluding the possibility of precipitation and crystalluria. Slow renal excretion results from a high degree of tubular reabsorption,4 and plasma protein binding is very high, providing a blood reservoir of the drug. Thus, sulfadimethoxine maintains higher blood levels than most other long-acting sulfonamides. Single, comparatively low doses of Albon give rapid and sustained therapeutic blood levels.1
To assure successful sulfonamide therapy (1) the drug must be given early in the course of the disease, and it must produce a high sulfonamide level in the body rapidly after administration, (2) therapeutically effective sulfonamide levels must be maintained in the body throughout the treatment period, (3) treatment should continue for a short period of time after the clinical signs have disappeared, and (4) the causative organisms must be sensitive to this class of drugs.
INDICATIONS AND USAGE: Albon is indicated for the treatment of respiratory, genitourinary tract, enteric, and soft tissue infections in dogs and cats:
tonsillitis
pharyngitis
bronchitis
pneumonia
cystitis
nephritis
metritis
pyometra
pustular dermatitis
anal gland infections
abscesses
wound infections
bacterial enteritis
canine salmonellosis
bacterial enteritis associated with coccidiosis in dogs
when caused by streptococci, staphylococci, escherichia, salmonella, klebsiella, proteus or shigella organisms sensitive to sulfadimethoxine.
Limitations: Sulfadimethoxine is not effective in viral or rickettsial infections, and as with any antibacterial agent, occasional failures in therapy may occur due to resistant microorganisms. The usual precautions in sulfonamide therapy should be observed.
WARNING: Not for human use.
PRECAUTION: During treatment period, make certain that animals maintain adequate water intake.
If animals show no improvement within 2 or 3 days, reevaluate your diagnosis.
DOSAGE AND ADMINISTRATION:
Initial Dose: 25 mg/lb (55 mg/kg) of animal body weight.
Subsequent Daily Doses: 12.5 mg/lb (27.5 mg/kg) of animal body weight.
For ease of administration in animals of varying weights, 3 tablet sizes are provided. The following table indicates how dosage may be adjusted depending on tablet size and body weight. Subsequent doses should be given at 24-hour intervals.
Tablet Size
Approximate Animal Weight
Initial Dose
25 mg/lb (55 mg/kg)
Subsequent Daily Doses
12.5 mg/lb (27.5 mg/kg)
125 mg
5 lb (2.2 kg)
1 tablet
1/2 tablet
250 mg
10 lb (4.5 kg)
1 tablet
1/2 tablet
500 mg
20 lb (9.1 kg)
1 tablet
1/2 tablet
Treatment may be initiated with Albon Injection 40% to obtain effective blood levels almost immediately or to facilitate treatment of the fractious animal.
Length of treatment depends on the clinical response. In most cases treatment for 3-5 days is adequate. Treatment should be continued until the animal is asymptomatic for 48 hours.
TOXICITY AND SAFETY: Data regarding acute and chronic toxicities of sulfadimethoxine indicate the drug is very safe. The LD50 in mice is greater than 2 g/kg of body weight when administered intraperitoneally and greater than 16 g/kg when administered orally. In dogs receiving massive single oral doses of 3.2 g/kg of body weight, diarrhea was the only adverse effect observed. Dogs given 160 mg/kg of body weight orally daily for 13 weeks showed no signs of toxicity.
STORAGE: Store at controlled room temperature 15�-30�C (59�-86�F).
HOW SUPPLIED: Albon Tablets are available in the following strengths for dogs and cats: 125 mg, 250 mg, or 500 mg sulfadimethoxine per tablet.
REFERENCES:
1. Data on file, Pfizer Animal Health.
2. Stowe CM: The sulfonamides. In Jones LM (ed), Veterinary Pharmacology and Therapeutics, Ames, Iowa, Iowa State University Press, chapter 33, 1965.
3. Bridges JW, Kirby MR, Walker SR, et al: Species differences in the metabolism of sulfadimethoxine. Biochem J 109:851, 1968.
4. Baggot JD: Some aspects of drug persistence in domestic animals. Res Vet Sci 11(2):130, 1970.
NADA #15-102, Approved by FDA for Tablets
Distributed by: Zoetis Inc., Kalamazoo, MI 49007
13908600
Revised: January 2013
CPN: 3690178.4

Albon Tabs 500mg B500 by Zoetis MFR
Zoetis Animal Health
SKU
033189
Unit
B500
MFR Code
10000294
Vendor SKUs
10000294
Case Qty
12
Rx
Yes
Size
B500
Form
tablet
Strength
500 mg
Brand
10000294 Albon (Sulfadimethoxi
Albon Tabs 500mg B500 by Zoetis MFR Zoetis Animal Health SKU 033189 Unit B500 MFR Code 10000294 Vendor SKUs 10000294 Case Qty 12 Rx Yes Size B500 Form tablet Strength 500 mg Brand

AmericanPharmaWholesale.com MFR
Zoetis Animal Health
SKU
033189
Unit
B500
MFR Code
10000294
Vendor SKUs
10000294
Case Qty
12
Rx
Yes
Size
B500
Form
tablet
Strength
500 mg
Brand
Alb
Albon Tabs 500mg B500 by Zoetis Item No.
AmericanPharmaWholesale.com MFR Zoetis Animal Health SKU 033189 Unit B500 MFR Code 10000294 Vendor SKUs 10000294 Case Qty 12 Rx Yes Size B500 Form tablet Strength 500 mg Brand Alb

We offer OTC, Rx, Medical Supplies and More.  Retail@wholesale MFR
Zoetis Animal Health
SKU
033189
Unit
B500
MFR Code
10000294
Vendor SKUs
10000294
Case Qty
12
Rx
Yes
Size
B500
Form
t
Zoetis Albon (Sulfadimethoxine
We offer OTC, Rx, Medical Supplies and More. Retail@wholesale MFR Zoetis Animal Health SKU 033189 Unit B500 MFR Code 10000294 Vendor SKUs 10000294 Case Qty 12 Rx Yes Size B500 Form t

Vet Rx Item Can Only Be Orderred By A Veterinarian Or Facility Staffed With. This Rx Item Can Only Be Used In Established Veterianarian/Client/Patient Relationships. Non Vet But Rx Item Can Only Be Or
Albon Tabs 500mg B500 By Zoetis
Vet Rx Item Can Only Be Orderred By A Veterinarian Or Facility Staffed With. This Rx Item Can Only Be Used In Established Veterianarian/Client/Patient Relationships. Non Vet But Rx Item Can Only Be Or