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Albon Oral Sulfadimethoxine Suspension 5% 2 oz By Zoetis

Albon Oral Suspension 5% 2OZ by Zoetis MFR
Zoetis Animal Health
SKU
032754
Unit
60ML
MFR Code
10000295
Vendor SKUs
10000295
Rx
Yes
Size
2oz
Form
liquid
Strength
0.05
Brand
Albon
AdAmericanPharmaWholesale.comWe offer OTC, Rx, Medical Supplies and More.  Retail@wholesaleAlbon Oral Suspension 5% 2 oz By Zoetis Item No.:Vet-Rx-MW 00032754

Albon Oral Sulfadimethoxine Suspension 5% 2 oz By Zoetis

$26.99$20.38

Albon Oral Suspension 5% 2 oz By Zoetis Item No.:Vet-Rx-MW 00032754 MFR
Zoetis Animal Health
SKU
032754
Unit
60ML
MFR Code
10000295
Vendor SKUs
10000295
Case Qty
24
Rx
Yes
Size
2oz
Form
liquid
Strength
0.05
Brand
Albon
Administration
oral
Species
canine | feline

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Albon Oral Suspension 5%
Albon Oral Suspension is indicated for the treatment of respiratory, genitourinary tract, enteric, and soft tissue infections in dogs and cats: tonsillitis, cystitis, pustular dermatitis, bacterial enteritis, pharyngitis, nephritis, anal gland infections, canine salmonellosis, bronchitis, metritis, abscesses, bacterial enteritis associated with coccidiosis in dogs, pneumonia, pyometra and wound infections when caused by streptococci, staphylococci, escherichia, salmonella, klebsiella, proteus or shigella organisms sensitive to sulfadimethoxine. Each tsp (5 mL) contains 250 mg sulfadimethoxine in a custard-flavored carrier.


ALBON�

Zoetis
(sulfadimethoxine)
Oral Suspension 5%
For the treatment of sulfadimethoxine-sensitive bacterial infections in dogs and cats and bacterial enteritis associated with coccidiosis in dogs.
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
DESCRIPTION: Albon is a low-dosage, rapidly absorbed, long-acting sulfonamide, effective for the treatment of a wide range of bacterial infections commonly encountered in dogs and cats.
Sulfadimethoxine is a white, almost tasteless and odorless compound. Chemically, it is N1-(2,6-dimethoxy-4-pyrimidinyl) sulfanilamide. The structural formula is:

CLINICAL PHARMACOLOGY: Sulfadimethoxine has been demonstrated clinically or in the laboratory to be effective against a variety of organisms, such as streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.1,2 These organisms have been demonstrated in respiratory, genitourinary, enteric, and soft tissue infections of dogs and cats.
The systemic sulfonamides which include sulfadimethoxine are bacteriostatic agents. Sulfonamides competitively inhibit bacterial synthesis of folic acid (pterolyglutamic acid) from para-aminobenzoic acid. Mammalian cells are capable of utilizing folic acid in the presence of sulfonamides.
The tissue distribution of sulfadimethoxine, as with all sulfonamides, is a function of plasma levels, degree of plasma protein binding, and subsequent passive distribution in the tissues of the lipid-soluble un-ionized form. The relative amounts are determined by both its pKa and by the pH of each tissue. Therefore, levels tend to be higher in less acid tissue and body fluids or those diseased tissues having high concentrations of leucocytes.2
In the dog, sulfadimethoxine is not acetylated as in most other animals, and it is excreted predominantly as the unchanged drug.3 Sulfadimethoxine has a relatively high solubility at the pH normally occurring in the kidney, precluding the possibility of precipitation and crystalluria. Slow renal excretion results from a high degree of tubular reabsorption,4 and plasma protein binding is very high, providing a blood reservoir of the drug. Thus, sulfadimethoxine maintains higher blood levels than most other long-acting sulfonamides. Single, comparatively low doses of Albon give rapid and sustained therapeutic blood levels.1
To assure successful sulfonamide therapy (1) the drug must be given early in the course of the disease, and it must produce a high sulfonamide level in the body rapidly after administration, (2) therapeutically effective sulfonamide levels must be maintained in the body throughout the treatment period, (3) treatment should continue for a short period of time after the clinical signs have disappeared, and (4) the causative organisms must be sensitive to this class of drugs.
INDICATIONS AND USAGE: Albon is indicated for the treatment of respiratory, genitourinary tract, enteric, and soft tissue infections in dogs and cats:
tonsillitis
pharyngitis
bronchitis
pneumonia
cystitis
nephritis
metritis
pyometra
pustular dermatitis
anal gland infections
abscesses
wound infections
bacterial enteritis
canine salmonellosis
bacterial enteritis associated with coccidiosis in dogs
when caused by streptococci, staphylococci, escherichia, salmonella, klebsiella, proteus or shigella organisms sensitive to sulfadimethoxine.
Limitations: Sulfadimethoxine is not effective in viral or rickettsial infections, and as with any antibacterial agent, occasional failures in therapy may occur due to resistant microorganisms. The usual precautions in sulfonamide therapy should be observed.
WARNING: Not for human use.
PRECAUTION: During treatment period, make certain that animals maintain adequate water intake.
If animals show no improvement within 2 or 3 days, reevaluate your diagnosis.
DOSAGE AND ADMINISTRATION:
Initial Dose: 25 mg/lb (55 mg/kg) of animal body weight.
Subsequent Daily Doses: 12.5 mg/lb (27.5 mg/kg) of animal body weight.
Dogs and cats should receive 1 teaspoonful of Albon Oral Suspension 5% per 10 lb of body weight (25 mg/lb or 55 mg/kg) as an initial dose, followed by 1/2 teaspoonful per 10 lb of body weight (12.5 mg/lb or 27.5 mg/kg) every 24 hours thereafter. Representative weights and doses are indicated in the following table:
Animal Weight
Initial Dose
25 mg/lb (55 mg/kg)
Subsequent Daily Doses
12.5 mg/lb (27.5 mg/kg)
5 lb (2.2 kg)
1/2 tsp (2 1/2 mL)
1/4 tsp (1 1/4 mL)
10 lb (4.5 kg)
1 tsp (5 mL)
1/2 tsp (2 1/2 mL)
20 lb (9.1 kg)
2 tsp (10 mL)
1 tsp (5 mL)
40 lb (18.2 kg)
4 tsp (20 mL)
2 tsp (10 mL)
80 lb (36.4 kg)
8 tsp (40 mL)
4 tsp (20 mL)
Treatment may be initiated with Albon Injection 40% to obtain effective blood levels almost immediately or to facilitate treatment of the fractious animal.
Length of treatment depends on the clinical response. In most cases treatment for 3-5 days is adequate. Treatment should be continued until the animal is asymptomatic for 48 hours.
TOXICITY AND SAFETY: Data regarding acute and chronic toxicities of sulfadimethoxine indicate the drug is very safe. The LD50 in mice is greater than 2 g/kg of body weight when administered intraperitoneally and greater than 16 g/kg when administered orally. In dogs receiving massive single oral doses of 3.2 g/kg of body weight, diarrhea was the only adverse effect observed. Dogs given 160 mg/kg of body weight orally daily for 13 weeks showed no signs of toxicity.
STORAGE: Store at controlled room temperature 15�-30�C (59�-86�F).
HOW SUPPLIED: Albon Oral Suspension is available in 60- and 473-mL bottles; each tsp (5 mL) contains 250 mg sulfadimethoxine in a custard-flavored carrier.
REFERENCES:
1. Data on file, Pfizer Animal Health.
2. Stowe CM: The sulfonamides. In Jones LM (ed), Veterinary Pharmacology and Therapeutics, Ames, Iowa, Iowa State University Press, chapter 33, 1965.
3. Bridges JW, Kirby MR, Walker SR, et al: Species differences in the metabolism of sulfadimethoxine. Biochem J 109:851, 1968.
4. Baggot JD: Some aspects of drug persistence in domestic animals. Res Vet Sci 11(2):130, 1970.
NADA #43-785, Approved by FDA
Distributed by: Zoetis Inc., Kalamazoo, MI 49007
PAA035062
Revised: January 2013
CPN: 3690177.4

Albon Oral Suspension 5% 2OZ by Zoetis MFR
Zoetis Animal Health
SKU
032754
Unit
60ML
MFR Code
10000295
Vendor SKUs
10000295
Rx
Yes
Size
2oz
Form
liquid
Strength
0.05
Brand
Albon
Ad
10000295 Albon Oral Sulfadimet
Albon Oral Suspension 5% 2OZ by Zoetis MFR Zoetis Animal Health SKU 032754 Unit 60ML MFR Code 10000295 Vendor SKUs 10000295 Rx Yes Size 2oz Form liquid Strength 0.05 Brand Albon Ad

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Albon Oral Suspension 5% 2 oz by Zoetis
AmericanPharmaWholesale.com

We offer OTC, Rx, Medical Supplies and More.  Retail@wholesale
Zoetis
We offer OTC, Rx, Medical Supplies and More. Retail@wholesale

Albon Oral Suspension 5% 2 oz By Zoetis Item No.:Vet-Rx-MW 00032754
Albon Oral Suspension 5% 2 oz By Zoetis
Albon Oral Suspension 5% 2 oz By Zoetis Item No.:Vet-Rx-MW 00032754