Please email us at [email protected] with our item No, NDC#, UPC# or the product link if you have any quetions. We are located in Oceanside, California. Search over 110,000 items by Name, Item No., NDC, UPC (without dashes) or by Mfg.Name. Please note, Prescription items can only be ordered by a Drug Manufacturer, Wholesaler, Hospital, Governmental Medical Facility, VA, Pharmacy, Physician, Physician Assistant, Nurse Practitioner, Dentist, Podiatrist, Optometrist, Veterinarian, Naturopath, Licensed Lab, Physical Therapist & Pharmacist in their scope of practice. No order will ship, unless you you have provided us the Medical License (and DEA Lic. in case of controlled drug) and we had verified that. Rx items can only be shipped to AZ, AR, CA, CT, DE, FL, GA, GU, HI, IL, KS, KY, LA, ME, MA, MI, NJ, NY, PA, PR, TX, TN, VA, WA, WI and WV. If you are an International Physician or Pharmacist, please contact us before ordering.


Menu

Rx Item-Scopolamine 1Mg/3Days Generic Transderm Scop 1.5Mg 3Day Patch 10 By Perr

NDC 00067-4345-04 UPC/GTIN No.3-00674-34504-2 Mfg.Part No.434504BRAND: TRANSDERM SCOP NDC: 00067-4345-04,67434504 UPC: 3-00674-34504-2,300674345042 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Scopolamine 1Mg/3Days Generic Transderm Scop 1.5Mg 3Day Patch 10 By Perr

$230.00$219.04

Item No.: RX686586 NDC No.67434504 UPC No.:300674345042 NDC No. 45802-0580-46 UPC/GTIN No. MPN 58046 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx686586 SCOPOLAMINE 1MG/3DAYS Generic Transderm Scop 1.5mg 3Day Patch 10 by Perrigo Pharma Item No. 686598 NDC No. 45802058046 UPC No. Other Name Tra

Have a question?

TRANSDERM SCOP- scopolamine patch, extended release
INDICATIONS AND USAGE

1.1 Motion Sickness
Transderm Scōp� is indicated in adults for prevention of nausea and vomiting associated with motion sickness.[see Clinical Studies (14.1)]

1.2 Post Operative Nausea and Vomiting (PONV)


Transderm Scōp� is indicated in adults for prevention of nausea and vomiting associated with recovery from anesthesia and/or opiate analgesia and surgery. [ see Clinical Studies (14.2)]

2 DOSAGE AND ADMINISTRATION

Each Transderm Scōp� patch is formulated to deliver in-vivo approximately 1mg of scopolamine over 3 days. Only one patch should be worn at any time. Do not cut the patch.

The patch should be applied only to the skin in the postauricular (hairless area behind one ear) area.

Handling

After the patch is applied on the dry skin behind the ear, the hands should be washed thoroughly with soap and water and dried. Upon removal, the patch should be discarded. To prevent any traces of scopolamine from coming into direct contact with the eyes, after administration of the patch, the hands and the application site should be washed thoroughly with soap and water and dried. [see How Supplied/Storage and Handling (16) and Patient Counseling Information (17)]

2.1 Initiation of Therapy
Motion sickness


To prevent the nausea and vomiting associated with motion sickness, one Transderm Scōp� patch (formulated to deliver approximately 1mg of scopolamine over 3 days) should be applied to the hairless area behind one ear at least 4 hours before the antiemetic effect is required.
Post Operative Nausea and Vomiting


To prevent post operative nausea and vomiting, one Transderm Scōp� patch should be applied the evening before scheduled surgery, except for caesarian section.

For caesarian section surgery, to minimize exposure of the newborn baby to the drug, apply the patch one hour prior to caesarian section.
DOSAGE FORMS AND STRENGTHS

The Transderm Scōp� system is a tan-colored circular flat patch which contains 1.5 mg of scopolamine base and is formulated to deliver in-vivo approximately 1mg of scopolamine over 3 days.

4 CONTRAINDICATIONS

Transderm Scōp� is contraindicated in the following populations:


Patients with angle closure glaucoma. [see Adverse Reactions (6)]

Persons who are hypersensitive to the drug scopolamine or other belladonna alkaloids or to any ingredient or component in the formulation or delivery system. [see Drug Interactions (7) and Description (11)]
5 WARNINGS AND PRECAUTIONS

5.1 Open Angle Glaucoma
Patients currently being treated for Open Angle Glaucoma

Glaucoma therapy in patients with open angle glaucoma should be monitored and may need to be adjusted during Transderm Scōp� use, as the mydriatic effect of scopolamine may cause an increase in intraocular pressure.

Patients should be advised to remove the patch immediately and promptly contact a physician in the event that they experience symptoms of acute angle closure glaucoma (pain and reddening of the eyes, accompanied by dilated pupils).

5.2 Temporary Dilation of the Pupil
Scopolamine can cause temporary dilation of the pupils and blurred vision if it comes in contact with the eyes.

Patients should be strongly advised to wash their hands thoroughly with soap and water immediately after handling the patch. [see Adverse Reactions (6)] In addition, it is important that used patches be disposed of properly to avoid contact with children or pets. [ see How Supplied/ Storage and Handling (16)]

5.3 Preexisting Gastrointestinal or Urinary Bladder Obstructions
Transderm Scōp� should be used with caution in patients with pyloric obstruction or urinary bladder neck obstruction. Caution should be exercised when administering an antiemetic or anticholinergic drug, including

Transderm Scōp� , to patients suspected of having intestinal obstruction.

Patients should be instructed to remove the patch if they develop any difficulties in urinating. [see Adverse Reactions (6)]

5.4 History of Seizures or Psychosis
Transderm Scōp� should be used with caution in patients with a history of seizures or psychosis since scopolamine can potentially aggravate both disorders.

5.5 Idiosyncratic Reactions
Idiosyncratic reactions may occur with ordinary therapeutic doses of scopolamine. The most serious of these that have been reported are: acute toxic psychosis, including confusion, agitation, speech disorder, hallucinations, paranoia, and delusions.
DESCRIPTION

The Transderm Scōp� (scopolamine) transdermal system is a circular flat patch designed for continuous release of scopolamine following application to an area of intact skin on the head, behind the ear. Each system contains 1.5 mg of scopolamine base. Scopolamine is α -(hydroxymethyl) benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo [3.3.1.0 2,4 ] non-7-yl ester. The empirical formula is C17 H21 NO4
Scopolamine is a viscous liquid that has a molecular weight of 303.35 and a pKa of 7.55-7.81. The Transderm Scōp� system is a film 0.2 mm thick and 2.5 cm2 , with four layers. Proceeding from the visible surface towards the surface attached to the skin, these layers are: (1) a backing layer of tan-colored, aluminized, polyester film; (2) a drug reservoir of scopolamine, light mineral oil, and polyisobutylene; (3) a microporous polypropylene membrane that controls the rate of delivery of scopolamine from the system to the skin surface; and (4) an adhesive formulation of mineral oil, polyisobutylene, and scopolamine. A protective peel strip of siliconized polyester, which covers the adhesive layer, is removed before the system is used. The inactive components, light mineral oil (12.4 mg) and polyisobutylene (11.4 mg), are not released from the system.
CLINICAL PHARMACOLOGY

12.1 Mechanism of Action
Scopolamine, a belladonna alkaloid, is an anticholinergic agent. Scopolamine acts: i) as a competitive inhibitor at postganglionic muscarinic receptor sites of the parasympathetic nervous system, and ii) on smooth muscles that respond to acetylcholine but lack cholinergic innervation. It has been suggested that scopolamine acts in the central nervous system (CNS) by blocking cholinergic transmission from the vestibular nuclei to higher centers in the CNS and from the reticular formation to the vomiting center. Scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, cause drowsiness, dilate the pupils, increase heart rate, and depress motor function.
PATIENT INFORMATION

Transderm Scōp� , pronounced tran(t)s-derm skōp

(scopolamine)

transdermal system patch

Read this Patient Information before you start using Transderm Scōp� and each time you get a refill. There may be new information. This information does not take the place of talking to your doctor about your medical condition or your treatment.



What is Transderm Scōp� ?

The Transderm Scōp� patch is a prescription medicine used for adults to:


help prevent nausea and vomiting from motion sickness

help prevent nausea and vomiting from anesthesia or taking opioid pain medicines after surgery
It is not known if Transderm Scōp� is safe or effective in children.

Who should not use Transderm Scōp� ?

Do not use Transderm Scōp� if you:


have an eye problem called angle closure glaucoma

if you are allergic to any of the ingredients in Transderm Scōp� or other medicines called belladonna alkaloids. See the end of this leaflet for a list of the ingredients in Transderm Scōp�. Ask your doctor if you are not sure.
What should I tell my doctor before using Transderm Scōp� ?

Before you use Transderm Scōp� , tell your doctor if you:


are scheduled to have a gastric secretion test

have glaucoma (increased pressure in the eye)

have liver or kidney problems

have problems with your stomach or intestines

have trouble urinating

have a history of seizures or psychosis

have any other medical conditions

are pregnant or plan to become pregnant. It is not known if Transderm Scōp� can harm your unborn baby.

are breast-feeding or plan to breast-feed. Transderm Scōp� can pass into your breast milk and may harm your baby. Talk to your doctor about the best way to feed your baby if you use Transderm Scōp�.
Tell your doctor about all the medicines you take , including prescription and non-prescription medicines, vitamins and herbal supplements. Transderm Scōp� may affect the way other medicines work, and other medicines may affect how Transderm Scōp� works. Medicines that you take by mouth may not be absorbed well while you use Transderm Scōp�.

Especially tell your doctor if you take:


a sedative or tranquilizer (medicines that make you sleepy)

an antidepressant medicine

an anticholinergic medicine, such as an allergy or cold medicine, a medicine to treat bladder or bowel spasms, certain asthma medicines, or other medicines for motion sickness.
Ask your doctor if you are not sure if your medicine is one that is listed above.

Know the medicines you take. Keep a list of them and show it to your doctor or pharmacist when you get a new medicine.

How should I use Transderm Scōp� ?

Use Transderm Scōp � exactly as your doctor tells you to use it.
Transderm Scōp� is a tan-colored circle shaped patch.
Wear only one patch at any time.
Do not cut the patch.
To help prevent nausea and vomiting from motion sickness:


Apply one Transderm Scōp� patch to your skin on a hairless area behind one ear at least 4 hours before the activity to prevent nausea and vomiting.

If the treatment is needed for longer than 3 days, remove the patch from the hairless area behind your ear. Get a new Transderm Scōp� patch and place it on the hairless area behind your other ear.
To help prevent nausea and vomiting after surgery:


Follow your doctor's instructions about when to apply Transderm Scōp� before your scheduled surgery.

The Transderm Scōp� patch should be left in place for 24 hours after surgery. After 24 hours the patch should be removed and thrown away.
Apply Transderm Scōp� as follows:

Inside the Transderm Scōp� package, you will find one Transderm Scōp� patch. A tan colored patch with a metallic (silver) sticky surface is adhered to a clear disposable backing (See Figure 1).

Figure 1
(click image for full-size original)
1. Select a hairless area of skin behind one of your ears. Avoid areas on your skin that may have cuts, pain or tenderness. Wipe the area of your skin with a clean, dry tissue.

2. Cut along dotted line on the Transderm Scōp� package to open (See Figure 2).

Figure 2
(click image for full-size original)
3. Remove the clear plastic backing from the tan-colored round patch (See Figure 3).

Figure 3
(click image for full-size original)
4. Avoid touching the metallic adhesive (sticky) surface on the patch with your hands (See Figure 4).

Figure 4
(click image for full-size original)
5. Apply the metallic adhesive surface of the patch firmly to the dry area of skin behind your ear. The tan-colored side of the patch should be facing up and showing (See Figure 5). Wash your hands with soap and water right away after applying the patch, so that any medicine from the patch that gets on your hands will not get into your eyes.

Figure 5
(click image for full-size original)
After removing the patch, be sure to wash your hands and the area behind your ear thoroughly with soap and water. Note that the used patch will still contain some of the active ingredient after use. To avoid accidental contact or ingestion by children or pets, fold the used patch in half with the sticky side together. Dispose in the trash out of the reach of children and pets.

If you use too much Transderm Scōp� , call your doctor or local poison control center, or go to the nearest hospital emergency room right away.

What should I avoid while using Transderm Scōp� ?


You should not drink alcohol while using Transderm Scōp�. It can increase your chances of having serious side effects.

You should not drive, operate heavy machinery, or do other dangerous activities until you know how Transderm Scōp� affects you.

You should not use Transderm Scōp� during a Magnetic Resonance Imaging scan (MRI). Remove Transderm Scōp� patch before undergoing an MRI; it can cause your skin to burn.

You should be careful if you use Transderm Scōp� while you participate in watersports because you may feel lost or confused (disoriented).

Limit contact with water while swimming and bathing because the Transderm Scōp� patch may fall off. If the patch falls off, throw it away and apply a new one on the hairless area behind your other ear.
What are the possible side effects of Transderm Scōp� ?

Transderm Scōp� may cause serious side effects, including:


angle closure glaucoma. If you have open angle glaucoma and use Transderm Scōp� , remove the patch and call a doctor right away if you get pain and reddening of your eyes with an increase in the size of your pupil (the small dark circle in the eye).

temporary increase in the size of your pupil and blurry vision , especially if Transderm Scōp� comes in contact with your eyes

difficulties in urinating

difficulties in food passing from the stomach to the small intestines, which may cause abdominal pain, nausea or vomiting.

worsening of seizures. Tell your doctor about any worsening of seizures while using Transderm Scōp�.

an unusual reaction called acute psychosis: Tell your doctor if you have any of these symptoms:

confusion

agitation

rambling speech

hallucinations (seeing or hearing things that are not there)

paranoid behaviors and delusions (false belief in something)

skin burns at the site of the patch. This can happen during a medical test called a Magnetic Resonance Imaging scan (MRI). Transderm Scōp� contains aluminum and should be removed from your skin before you have an MRI.
The most common side effects of using Transderm Scōp� include:


dry mouth

drowsiness

disorientation (confusion)

blurred vision

pharyngitis

memory trouble

dizziness

restlessness

agitation

problems urinating

skin rashes or redness, application site burning

dry itchy, or reddened whites of the eyes, and eye pain

NDC 00067-4345-04 UPC/GTIN No.3-00674-34504-2 Mfg.Part No.434504
RX ITEM-Scopolamine 1Mg/3Days Generic Tr
NDC 00067-4345-04 UPC/GTIN No.3-00674-34504-2 Mfg.Part No.434504

BRAND: TRANSDERM SCOP NDC: 00067-4345-04,67434504 UPC: 3-00674-34504-2,300674345042
Scopolamine 1Mg/3Days Generic Transderm
BRAND: TRANSDERM SCOP NDC: 00067-4345-04,67434504 UPC: 3-00674-34504-2,300674345042

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
Click above for all Transderm Scop
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
Buy More Save More!
Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.