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RX ITEM-Zorbtive 8.8Mg Vial 7 By Serono Labs

NDC 44087-3388-07 UPC/GTIN No.3-44087-33887-9 Mfg.Part No.338807BRAND: ZORBTIVE  NDC: 44087-3388-07,44087338807 UPC: 3-44087-33887-9,344087338879 Serono Labs, Inc.Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Zorbtive 8.8Mg Vial 7 By Serono Labs

$9287.11$9199.00

item No.:RX803167 NDC No.44087338807 UPC No.:344087338879 NDC No.44087-3388-07 UPC/GTIN No.3-44087-33887-9 MPN 338807 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No.Rx803167 Zorbtive 8.8mg Vial 7 by Serono Labs, Item No.3803167 NDC No.44087338807 UPC No.344087338879 Other Name Zorbtive Therapeutic

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ZORBTIVE - somatropin (rdna origin)
EMD Serono, Inc.
DESCRIPTION

ZorbtiveŽ [somatropin (rDNA origin) for injection] is a human growth hormone (hGH) produced by recombinant DNA technology. ZorbtiveŽ has 191 amino acid residues and a molecular weight of 22,125 daltons. Its amino acid sequence and structure are identical to the dominant form of human pituitary GH. ZorbtiveŽ is produced by a mammalian cell line (mouse C127) that has been modified by the addition of the hGH gene. ZorbtiveŽ is secreted directly through the cell membrane into the cell-culture medium for collection and purification.
ZorbtiveŽ is available in 8.8 mg vials for multi-dose administration. Each 8.8 mg vial contains 8.8 mg somatropin, 60.19 mg sucrose and 2.05 mg phosphoric acid. The pH is adjusted with sodium hydroxide or phosphoric acid to give a pH of 7.4 to 8.5 after reconstitution.

CLINICAL PHARMACOLOGY

ZorbtiveŽ [somatropin (rDNA origin) for injection] is an anabolic and anticatabolic agent which exerts its influence by interacting with specific receptors on a variety of cell types including myocytes, hepatocytes, adipocytes, lymphocytes, and hematopoietic cells. Some, but not all of its effects, are mediated by insulin-like growth factor-1 (IGF-1).

MECHANISM OF ACTION – IN SHORT BOWEL SYNDROME (SBS) PATIENTS
Intestinal mucosa contains receptors for growth hormone and for insulin-like growth factor-1 (IGF-1), which is known to mediate many of the cellular actions of growth hormone. Thus, the actions of growth hormone on the gut may be direct or mediated via the local or systemic production of IGF-1.

In human clinical studies the administration of growth hormone has been shown to enhance the transmucosal transport of water, electrolytes, and nutrients.
DOSAGE AND ADMINISTRATION

ZorbtiveŽ should be administered to patients with short bowel syndrome (SBS) at a dose of approximately 0.1 mg/kg subcutaneously daily to a maximum of 8 mg daily. Administration for more than 4 weeks has not been adequately studied.



Injections should be administered daily for 4 weeks. Changes to concomitant medications should be avoided. Patients and physicians should monitor for adverse events. Treat moderate fluid retention and arthralgias symptomatically or dose reduce by 50%. Discontinue ZorbtiveŽ for up to 5 days for severe toxicities. Upon resolution of symptoms, resume at 50% of original dose. Permanently discontinue treatment if severe toxicity recurs or does not disappear within 5 days.

Injection sites should be rotated.

Safety and effectiveness in pediatric patients with short bowel syndrome have not been established.

NDC 44087-3388-07 UPC/GTIN No.3-44087-33887-9 Mfg.Part No.338807
RX ITEM-Zorbtive 8.8Mg Vial 7 By Serono
NDC 44087-3388-07 UPC/GTIN No.3-44087-33887-9 Mfg.Part No.338807

BRAND: ZORBTIVE  NDC: 44087-3388-07,44087338807 UPC: 3-44087-33887-9,344087338879 Serono Labs, Inc.
Zorbtive 8.8Mg Vial 7 By Serono Labs
BRAND: ZORBTIVE NDC: 44087-3388-07,44087338807 UPC: 3-44087-33887-9,344087338879 Serono Labs, Inc.

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
SOMATROPIN SUB-Q VIAL 8.8
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.