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Rx Item-Zomig Zmt 5Mg Tab 3 By Impax Pharma

NDC 64896-0692-50 UPC/GTIN No.3-64896-69250-4 Mfg.Part No.69250BRAND: ZOMIG NDC: 64896-0692-50,64896069250 UPC: 3-64896-69250-4,364896692504 Impax PharmaceuticalsOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Zomig Zmt 5Mg Tab 3 By Impax Pharma

$465.70$423.12

Item No.: RX182523 NDC No.64896069250 UPC No.:364896692504 NDC No.64896-0692-50 UPC/GTIN No.3-64896-69250-4 MPN 69250 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No.Rx182523 Zomig Zmt 5mg Tab 3 by Impax Pharma Item No.3182523 NDC No.64896069250 UPC No.364896692504 Other Name Zomig Zmt Therapeutic

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ZOMIG- zolmitriptan spray, metered
Impax Laboratories, Inc.
ZOLMITRIPTAN- zolmitriptan tablet, film coated
Glenmark Generics Inc.,USA
INDICATIONS AND USAGE
Zolmitriptan tablets are indicated for the acute treatment of migraine with or without aura in adults.
Limitations of Use

Only use zolmitriptan tablets if a clear diagnosis of migraine has been established. If a patient has no response to zolmitriptan tablets treatment for the first migraine attack, reconsider the diagnosis of migraine before zolmitriptan tablets are administered to treat any subsequent attacksZolmitriptan tablets are not indicated for the prevention of migraine attacks
Safety and effectiveness of zolmitriptan tablets have not been established for cluster headache.


ZOMIG Nasal Spray is indicated for the acute treatment of migraine with or without aura in adults ?and pediatric patients 12 years of age and older.
Only use ZOMIG if a clear diagnosis of migraine has been established. If a patient has no response to ZOMIG treatment for the first migraine attack, reconsider the diagnosis of migraine before ZOMIG is administered to treat any subsequent attacks.
ZOMIG is not indicated for the prevention of migraine attacks.
Safety and effectiveness of ZOMIG have not been established for cluster headache.
Not recommended in patients with moderate or severe hepatic impairment [see Dosage and Administration (2.2)].
2 DOSAGE AND ADMINISTRATION
2.1 Dosing Information
The recommended starting dose for ZOMIG nasal spray ?in adult and pediatric patients 12 years of age and older is 2.5 mg. As the individual response to ZOMIG nasal spray may vary, the dose should be adjusted on an individual basis. The maximum recommended single dose of ZOMIG is 5 mg.
If the migraine has not resolved by 2 hours after taking ZOMIG, or returns after a transient improvement, another dose may be administered at least 2 hours after the previous dose.
The maximum daily dose should not exceed 10 mg in any 24?hour period.
The safety of ZOMIG in the treatment of an average of more than four headaches in a 30?day period has not been established
Nasal Spray 2.5 mg and 5 mg.
The recommended starting dose of zolmitriptan tablets is 1.25 mg or 2.5 mg. The 1.25 mg dose can be achieved by manually breaking the functionally-scored 2.5 mg tablet in half. The maximum recommended single dose of zolmitriptan tablets is 5 mg.
In controlled clinical trials, a greater proportion of patients had headache response following a 2.5 mg or 5 mg dose than following a 1 mg dose. There was little added benefit from the 5 mg dose compared to the 2.5 mg dose, but adverse reactions were more frequent with the 5 mg dose.
If the migraine has not resolved by 2 hours after taking zolmitriptan tablets, or returns after a transient improvement, a second dose may be administered at least 2 hours after the first dose. The maximum daily dose is 10 mg in any 24-hour period.
DESCRIPTION
Zolmitriptan tablets contain zolmitriptan, which is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D ) receptor agonist. Zolmitriptan is chemically designated as (S)-4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-2-oxazolidinone
CLINICAL PHARMACOLOGY
12.1 Mechanism of Action
Zolmitriptan binds with high affinity to human recombinant 5-HT1D and 5-HT1B receptors, and moderate affinity for 5-HT1A receptors. The N-desmethyl metabolite also has high affinity for 5-HT1B/1D and moderate affinity for 5-HT1A receptors.
Migraines are likely due to local cranial vasodilatation and/or to the release of sensory neuropeptides (vasoactive intestinal peptide, substance P and calcitonin gene-related peptide) through nerve endings in the trigeminal system. The therapeutic activity of zolmitriptan for the treatment of migraine headache is thought to be due to the agonist effects at the 5-HT1B/1D receptors on intracranial blood vessels (including the arteriovenous anastomoses) and sensory nerves of the trigeminal system which result in cranial vessel constriction and inhibition of pro-inflammatory neuropeptide release.


NDC 64896-0692-50 UPC/GTIN No.3-64896-69250-4 Mfg.Part No.69250
RX ITEM-Zomig Zmt 5Mg Tab 3 By Impax Pha
NDC 64896-0692-50 UPC/GTIN No.3-64896-69250-4 Mfg.Part No.69250

BRAND: ZOMIG NDC: 64896-0692-50,64896069250 UPC: 3-64896-69250-4,364896692504 Impax Pharmaceuticals
Zomig Zmt 5Mg Tab 3 By Impax Pharma
BRAND: ZOMIG NDC: 64896-0692-50,64896069250 UPC: 3-64896-69250-4,364896692504 Impax Pharmaceuticals

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
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