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RX ITEM-Zirgan 0.15% Gel 5Gm By Valeant Pharma

NDC 24208-0535-35 UPC/GTIN No.3-24208-53535-6 Mfg.Part No.53535BRAND: ZIRGAN NDC: 24208-0535-35,24208053535 UPC: 3-24208-53535-6,324208535356 Valeant PharmaOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Zirgan 0.15% Gel 5Gm By Valeant Pharma

$397.66$363.85

item No.:RX046821 NDC No.24208053535 UPC No.:324208535356 NDC No.24208-0535-35 UPC/GTIN No.3-24208-53535-6 MPN 53535 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No.Rx046821 Zirgan 0.15% Gel 5gm by Valeant Pharma Item No.3046821 NDC No.24208053535 UPC No.324208535356 Other Name Zirgan Therapeutic Co

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ZIRGAN- ganciclovir gel
Bausch & Lomb Incorporated

1 INDICATIONS AND USAGE

ZIRGAN (ganciclovir ophthalmic gel) 0.15% is indicated for the treatment of acute herpetic keratitis (dendritic ulcers).
DOSAGE AND ADMINISTRATION



The recommended dosing regimen for ZIRGAN is 1 drop in the affected eye 5 times per day (approximately every 3 hours while awake) until the corneal ulcer heals, and then 1 drop 3 times per day for 7 days.

3 DOSAGE FORMS AND STRENGTHS

ZIRGAN contains 0.15% of ganciclovir in a sterile preserved topical ophthalmic gel.

4 CONTRAINDICATIONS

None.

5 WARNINGS AND PRECAUTIONS

5.1 Topical Ophthalmic Use Only
ZIRGAN is indicated for topical ophthalmic use only.

5.2 Avoidance of Contact Lenses
Patients should not wear contact lenses if they have signs or symptoms of herpetic keratitis or during the course of therapy with ZIRGAN.

6 ADVERSE REACTIONS

Most common adverse reactions reported in patients were blurred vision (60%), eye irritation (20%), punctate keratitis (5%), and conjunctival hyperemia (5%).

8 USE IN SPECIFIC POPULATIONS

8.1 Pregnancy Teratogenic Effects
Pregnancy Category C: Ganciclovir has been shown to be embryotoxic in rabbits and mice following intravenous administration and teratogenic in rabbits.
DESCRIPTION

ZIRGAN (ganciclovir ophthalmic gel) 0.15% contains a sterile, topical antiviral for ophthalmic use. The chemical name is 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (CAS number 82410-32-0).

Mechanism of Action
ZIRGAN (ganciclovir ophthalmic gel) 0.15% contains the active ingredient, ganciclovir, which is a guanosine derivative that, upon phosphorylation, inhibits DNA replication by herpes simplex viruses (HSV). Ganciclovir is transformed by viral and cellular thymidine kinases (TK) to ganciclovir triphosphate, which works as an antiviral agent by inhibiting the synthesis of viral DNA in 2 ways: competitive inhibition of viral DNA-polymerase and direct incorporation into viral primer strand DNA, resulting in DNA chain termination and prevention of replication.
HOW SUPPLIED/STORAGE AND HANDLING

ZIRGAN is supplied as 5 grams of a sterile, preserved, clear, colorless, topical ophthalmic gel containing 0.15% of ganciclovir in a polycoated aluminum tube with a white polyethylene tip and cap and protective band (NDC 24208-535-35).

Storage

Store at 15°C-25°C (59°F-77°F). Do not freeze.

NDC 24208-0535-35 UPC/GTIN No.3-24208-53535-6 Mfg.Part No.53535
RX ITEM-Zirgan 0.15% Gel 5Gm By Valeant
NDC 24208-0535-35 UPC/GTIN No.3-24208-53535-6 Mfg.Part No.53535

BRAND: ZIRGAN NDC: 24208-0535-35,24208053535 UPC: 3-24208-53535-6,324208535356 Valeant Pharma
Zirgan 0.15% Gel 5Gm By Valeant Pharma
BRAND: ZIRGAN NDC: 24208-0535-35,24208053535 UPC: 3-24208-53535-6,324208535356 Valeant Pharma

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
GANCICLOVIR OPHTHALMIC GE
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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