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RX ITEM-Sfrowasa 4 G 60 Ml Enm 7X60Ml By Meda Pharma

NDC 68220-0022-07 UPC/GTIN No.3-68220-02207-4 Mfg.Part No.2207BRAND: SFROWASA NDC: 68220-0022-07,68220002207 UPC: 3-68220-02207-4,368220022074 Meda PharmaceuticalsOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Sfrowasa 4 G 60 Ml Enm 7X60Ml By Meda Pharma

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Item No.: RX042616 NDC No.68220002207 UPC No.:368220022074 NDC No.68220-0022-07 UPC/GTIN No.3-68220-02207-4 MPN 2207 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No.Rx042616 Sfrowasa 4 G/60 ml Enm 7X60ml by Meda Pharma Item No.3042616 NDC No.68220002207 UPC No.368220022074 Other Name Mesalamine Caps

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SFROWASA SULFITE-FREE FORMULATION- mesalamine suspension
MEDA Pharmaceuticals
DESCRIPTION

The active ingredient in sfROWASA� (mesalamine) Rectal Suspension, a disposable (60 mL) unit, is mesalamine, also known as 5-aminosalicylic acid (5-ASA). Chemically, mesalamine is 5-amino-2-hydroxybenzoic acid.

The empirical formula is C7 H7 NO3 , representing a molecular weight of 153.14.

Each rectal suspension unit contains 4 grams of mesalamine. In addition to mesalamine the preparation contains the inactive ingredients carbomer 934P, edetate disodium, potassium acetate, purified water, sodium benzoate, and xanthan gum. Sodium benzoate is added as a preservative. The disposable unit consists of an applicator tip protected by a polyethylene cover and lubricated with USP white petrolatum. The unit has a one-way valve to prevent back flow of the dispensed product.
CLINICAL PHARMACOLOGY

Sulfasalazine is split by bacterial action in the colon into sulfapyridine (SP) and mesalamine (5-ASA). It is thought that the mesalamine component is therapeutically active in ulcerative colitis [A.K. Azad Khan et al, Lancet 2:892-895 (1977)]. The usual oral dose of sulfasalazine for active ulcerative colitis in adults is two to four grams per day in divided doses. Four grams of sulfasalazine provide 1.6 g of free mesalamine to the colon. Each sfROWASA� (mesalamine) Rectal Suspension delivers up to 4 g of mesalamine to the left side of the colon.

The mechanism of action of mesalamine (and sulfasalazine) is unknown, but appears to be topical rather than systemic. Mucosal production of arachidonic acid (AA) metabolites, both through the cyclooxygenase pathways, i.e., prostanoids, and through the lipoxygenase pathways, i.e., leukotrienes (LTs) and hydroxyeicosatetraenoic acids (HETEs) is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalamine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin (PG) production in the colon.

NDC 68220-0022-07 UPC/GTIN No.3-68220-02207-4 Mfg.Part No.2207
RX ITEM-Sfrowasa 4 G 60 Ml Enm 7X60Ml By
NDC 68220-0022-07 UPC/GTIN No.3-68220-02207-4 Mfg.Part No.2207

BRAND: SFROWASA NDC: 68220-0022-07,68220002207 UPC: 3-68220-02207-4,368220022074 Meda Pharmaceuticals
Sfrowasa 4 G 60 Ml Enm 7X60Ml By Meda Ph
BRAND: SFROWASA NDC: 68220-0022-07,68220002207 UPC: 3-68220-02207-4,368220022074 Meda Pharmaceuticals

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
MESALAMINE RECTAL ENEMA 4
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.