Rx Item-Rimso-50 50% Solution 50Ml By Mylan Institutional

Clinical Information
Gen. Code and Des.
64336 dimethyl sulfoxide INTRAVESIC SOLUTION 50 %
GCN and Des.
13356 dimethyl sulfoxide INTRAVESIC SOLUTION 50 %
Strength
Dose Form
SOLUTION, NON-ORAL
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
40360000 IRRIGATING SOLUTIONS
Active Ingredients
2883 dimethyl sulfoxide 67685





RIMSO-50- dimethyl sulfoxide irrigant
Mylan Institutional LLC

PRESCRIBING INFORMATION

Rx only

DESCRIPTION

RIMSO-50� (dimethyl sulfoxide) (DMSO) 50% w/w Aqueous Solution for intravesical instillation.



Each mL contains 0.54 gm dimethyl sulfoxide STERILE AND NON-PYROGENIC.

Intravesical instillation for the treatment of interstitial cystitis.

NOT FOR INTRAMUSCULAR OR INTRAVENOUS INJECTION.

The active component of RIMSO-50� is dimethyl sulfoxide which has the empirical formula C2 H6 OS, and is structurally represented as:

Chemical Structure
Dimethyl sulfoxide is a clear, colorless and essentially odorless liquid which is miscible with water and most organic solvents. Other physical characteristics include: molecular weight 78.13, melting point 18.3� C, and a specific gravity of 1.096.

CLINICAL PHARMACOLOGY

Dimethyl sulfoxide is metabolised in man by oxidation to dimethyl sulfone or by reduction to dimethyl sulfide. Dimethyl sulfoxide and dimethyl sulfone are excreted in the urine and feces. Dimethyl sulfide is eliminated through the breath and skin and is responsible for the characteristic odor from patients on dimethyl sulfoxide medication. Dimethyl sulfone can persist in serum for longer than two weeks after a single intravesical instillation. No residual accumulation of dimethyl sulfoxide has occurred in man or lower animals who have received treatment for protracted periods of time. Following topical application, dimethyl sulfoxide is absorbed and generally distributed in the tissues and body fluids.

INDICATIONS AND USAGE

RIMSO-50� (dimethyl sulfoxide) is indicated for the symptomatic relief of patients with interstitial cystitis. RIMSO-50� has not been approved as being safe and effective for any other indication. There is no clinical evidence of effectiveness of dimethyl sulfoxide in the treatment of bacterial infections of the urinary tract.

CONTRAINDICATIONS

Rimso-50 50% Solution 50Ml By
Item No.: RX400051 NDC No.67457017750 67457-177-50 6745717750 UPC No.:367457177502 NDC No.67457-0177-50 UPC/GTIN No.3-67457-17750-2 MPN 17750

Rimso-50 50% Solution 50Ml By Mylan Inst
Item No.: RX400051 NDC No.67457017750 67457-177-50 6745717750 UPC No.:367457177502 NDC No.67457-0177-50 UPC/GTIN No.3-67457-17750-2 MPN 17750

DIMETHYL SULFOXIDE INTRAV
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

RX ITEM-Rimso-50 50% Solution 50Ml By My
Item No.: RX400051 NDC No.67457017750 67457-177-50 6745717750 UPC No.:367457177502 NDC No.67457-0177-50 UPC/GTIN No.3-67457-17750-2 MPN 17750

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