Rx Item-Repaglinide 1Mg Tab 100 By Perrigo Pharma Gen Prandin

Clinical Information
Gen. Code and Des.
38907 repaglinide ORAL TABLET 1 MG
GCN and Des.
26312 repaglinide ORAL TABLET 1 MG
Strength
1MG
Dose Form
TABLET
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
68201600 MEGLITINIDES
Active Ingredients
7421 repaglinide 135062021
Inactive Ingredients
2537 povidone 9003398




PRANDIN- repaglinide tablet
Physicians Total Care, Inc.

DESCRIPTION

PRANDIN� (repaglinide) is an oral blood glucose-lowering drug of the meglitinide class used in the management of type 2 diabetes mellitus (also known as non-insulin dependent diabetes mellitus or NIDDM). Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl) phenyl)-butyl) amino)-2-oxoethyl) benzoic acid, is chemically unrelated to the oral sulfonylurea insulin secretagogues.
CLINICAL PHARMACOLOGY

Mechanism of Action
Repaglinide lowers blood glucose levels by stimulating the release of insulin from the pancreas. This action is dependent upon functioning beta (�) cells in the pancreatic islets. Insulin release is glucose-dependent and diminishes at low glucose concentrations.

Repaglinide closes ATP-dependent potassium channels in the �-cell membrane by binding at characterizable sites. This potassium channel blockade depolarizes the �-cell, which leads to an opening of calcium channels. The resulting increased calcium influx induces insulin secretion. The ion channel mechanism is highly tissue selective with low affinity for heart and skeletal muscle.
INDICATIONS AND USAGE

PRANDIN is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Repaglinide 1Mg Tab 100 By Per
BRAND: REPAGLINIDE NDC: 00574-0241-01,574024101 UPC: 3-05740-24101-1,305740241011

Repaglinide 1Mg Tab 100 By Perrigo Pharm
BRAND: REPAGLINIDE NDC: 00574-0241-01,574024101 UPC: 3-05740-24101-1,305740241011

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RX ITEM-Repaglinide 1Mg Tab 100 By Perri
NDC 00574-0241-01 UPC/GTIN No.3-05740-24101-1 Mfg.Part No.24101