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Rx Item-Prostin E2 20Mg Suppository 5 By Pfizer Pharma

NDC 00009-0827-03 UPC/GTIN No.3-00090-82703-8 Mfg.Part No.82703

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Rx Item-Prostin E2 20Mg Suppository 5 By Pfizer Pharma

$13315.26$12681.20

Item No.: RX004580 NDC No.9082703 UPC No.:300090827038 NDC No. 00009-0827-03 UPC/GTIN No. 3-00090-82703-8 MPN 82703 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx004580 Prostin E2 20mg Sup 5 by Pfizer Pharm Item No. 3004580 NDC No. 00009082703 UPC No. 300090827038 Other Name Prostin E2, dinopro

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PROSTIN E2- dinoprostone suppository
Pharmacia and Upjohn Company LLC

DESCRIPTION

PROSTIN E2 Vaginal Suppository, an oxytocic, contains dinoprostone as the naturally occurring prostaglandin E2 (PGE2). The molecular formula is C20 H32 O5 . The molecular weight of dinoprostone is 352.5. Dinoprostone occurs as a white crystalline powder. It has a melting point within the range of 64� to 71�C. Dinoprostone is soluble in ethanol and in 25% ethanol in water. It is soluble in water to the extent of 130 mg/100 mL.

Each suppository contains 20 mg of dinoprostone in a mixture of glycerides of fatty acids.

CLINICAL PHARMACOLOGY

PROSTIN E2 Vaginal Suppository administered intravaginally stimulates the myometrium of the gravid uterus to contract in a manner that is similar to the contractions seen in the term uterus during labor. Whether or not this action results from a direct effect of dinoprostone on the myometrium has not been determined with certainty at this time. Nonetheless, the myometrial contractions induced by the vaginal administration of dinoprostone are sufficient to produce evacuation of the products of conception from the uterus in the majority of cases.

Dinoprostone is also capable of stimulating the smooth muscle of the gastrointestinal tract of man. This activity may be responsible for the vomiting and/or diarrhea that is not uncommon when dinoprostone is used to terminate pregnancy.

Its chemical name is (5Z,11? ,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid

RX ITEM-Prostin E2 20Mg Suppository 5 By
NDC 00009-0827-03 UPC/GTIN No.3-00090-82703-8 Mfg.Part No.82703

Prostin E2 20Mg Suppository 5 By Pfizer
BRAND: PROSTIN-E2 NDC: 00009-0827-03,9082703 UPC: 3-00090-82703-8,300090827038 Pfizer Pharmaceutical

DINOPROSTONE VAGINAL SUPP
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