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Rx Item-Prazosin 5Mg Cap 250 By Mylan Pharma

NDC 00378-3205-25 UPC/GTIN No.3-03783-20525-1 Mfg.Part No.320525BRAND: PRAZOSIN NDC: 00378-3205-25,378320525 UPC: 3-03783-20525-1,303783205251 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Prazosin 5Mg Cap 250 By Mylan Pharma

$545.69$374.18

Item No.: RX509174 NDC No.378320525 UPC No.:303783205251 NDC No. 00378-3205-25 UPC/GTIN No. 3-03783-20525-1 MPN 320525 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx509174 Prazosin 5mg Cap 250 by Mylan Pharma Item No. 3509174 NDC No. 00378320525 UPC No. 303783205251 Other Name Minipress, Praz

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MINIPRESS- prazosin hydrochloride capsule
Pfizer Laboratories Div Pfizer Inc


For Oral Use

DESCRIPTION

MINIPRESS� (prazosin hydrochloride), a quinazoline derivative, is the first of a new chemical class of antihypertensives. It is the hydrochloride salt of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl) piperazine.
Molecular formula C19 H21 N5 O4 �HCl

It is a white, crystalline substance, slightly soluble in water and isotonic saline, and has a molecular weight of 419.87. Each 1 mg capsule of MINIPRESS for oral use contains drug equivalent to 1 mg free base.

Inert ingredients in the formulations are: hard gelatin capsules (which may contain Blue 1, Red 3, Red 28, Red 40, and other inert ingredients); magnesium stearate; sodium lauryl sulfate; starch; sucrose.

CLINICAL PHARMACOLOGY

The exact mechanism of the hypotensive action of prazosin is unknown. Prazosin causes a decrease in total peripheral resistance and was originally thought to have a direct relaxant action on vascular smooth muscle. Recent animal studies, however, have suggested that the vasodilator effect of prazosin is also related to blockade of postsynaptic alpha-adrenoceptors. The results of dog forelimb experiments demonstrate that the peripheral vasodilator effect of prazosin is confined mainly to the level of the resistance vessels (arterioles). Unlike conventional alpha-blockers, the antihypertensive action of prazosin is usually not accompanied by a reflex tachycardia. Tolerance has not been observed to develop in long term therapy.
Minipress Indications and Usage

MINIPRESS is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including this drug.
DOSAGE AND ADMINISTRATION

The dose of MINIPRESS should be adjusted according to the patient�s individual blood pressure response. The following is a guide to its administration:

Initial Dose
1 mg two or three times a day
Maintenance Dose
Dosage may be slowly increased to a total daily dose of 20 mg given in divided doses. The therapeutic dosages most commonly employed have ranged from 6 mg to 15 mg daily given in divided doses. Doses higher than 20 mg usually do not increase efficacy, however a few patients may benefit from further increases up to a daily dose of 40 mg given in divided doses. After initial titration some patients can be maintained adequately on a twice daily dosage regimen.
Use With Other Drugs
When adding a diuretic or other antihypertensive agent, the dose of MINIPRESS should be reduced to 1 mg or 2 mg three times a day and retitration then carried out.

Concomitant administration of MINIPRESS with a PDE-5 inhibitor can result in additive blood pressure lowering effects and symptomatic hypotension; therefore, PDE-5 inhibitor therapy should be initiated at the lowest dose in patients taking MINIPRESS.

NDC 00378-3205-25 UPC/GTIN No.3-03783-20525-1 Mfg.Part No.320525
RX ITEM-Prazosin 5Mg Cap 250 By Mylan Ph
NDC 00378-3205-25 UPC/GTIN No.3-03783-20525-1 Mfg.Part No.320525

BRAND: PRAZOSIN NDC: 00378-3205-25,378320525 UPC: 3-03783-20525-1,303783205251
Prazosin 5Mg Cap 250 By Mylan Pharma
BRAND: PRAZOSIN NDC: 00378-3205-25,378320525 UPC: 3-03783-20525-1,303783205251

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
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Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.