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RX ITEM-Octreotide 100 Mcg/Ml Vial 10X1Ml By Fresenius Kabi USA

NDC 63323-0376-01 UPC/GTIN No.3-63323-37601-7 Mfg.Part No.37601BRAND: OCTREOTIDE NDC: 63323-0376-01,63323037601 UPC: 3-63323-37601-7,363323376017 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Octreotide 100 Mcg/Ml Vial 10X1Ml By Fresenius Kabi USA

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item No.:RX637569 NDC No.63323037601 UPC No.:363323376017 NDC No. 63323-0376-01 UPC/GTIN No. 3-63323-37601-7 MPN 37601 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No. Rx637569 Octreotide 100 mcg/ml Vial 10X1ml by Fresenius Kabi USA Item No. 3637569 NDC No. 63323037601 UPC No. 363323376017 Other Nam

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SANDOSTATIN- octreotide acetate injection, solution
Novartis Pharmaceuticals Corporation
DESCRIPTION

Sandostatin� (octreotide acetate) Injection, a cyclic octapeptide prepared as a clear sterile solution of octreotide, acetate salt, in a buffered lactic acid solution for administration by deep subcutaneous (intrafat) or intravenous injection. Octreotide acetate, known chemically as L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2?7)-disulfide; [R-(R*, R*)] acetate salt, is a long-acting octapeptide with pharmacologic actions mimicking those of the natural hormone somatostatin.

Sandostatin Injection is available as: sterile 1-mL ampuls in 3 strengths, containing 50, 100, or 500 mcg octreotide (as acetate), and sterile 5-mL multi-dose vials in 2 strengths, containing 200 and 1000 mcg/mL of octreotide (as acetate).

Each ampul also contains:

lactic acid, USP 3.4 mg

mannitol, USP 45 mg

sodium bicarbonate, USP qs to pH 4.2 � 0.3

water for injection, USP qs to 1 mL

Each mL of the multi-dose vials also contains:

lactic acid, USP 3.4 mg

mannitol, USP 45 mg

phenol, USP 5.0 mg

sodium bicarbonate, USP qs to pH 4.2 � 0.3

water for injection, USP qs to 1 mL

Lactic acid and sodium bicarbonate are added to provide a buffered solution, pH to 4.2 � 0.3.

The molecular weight of octreotide acetate is 1019.3 (free peptide, C49 H66 N10 O10 S2 ) and its amino acid sequence is:
octreotide acetate amino acid sequence
(click image for full-size original)
CLINICAL PHARMACOLOGY

Sandostatin� (octreotide acetate) exerts pharmacologic actions similar to the natural hormone, somatostatin. It is an even more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Like somatostatin, it also suppresses LH response to GnRH, decreases splanchnic blood flow, and inhibits release of serotonin, gastrin, vasoactive intestinal peptide, secretin, motilin, and pancreatic polypeptide.

By virtue of these pharmacological actions, Sandostatin has been used to treat the symptoms associated with metastatic carcinoid tumors (flushing and diarrhea), and Vasoactive Intestinal Peptide (VIP) secreting adenomas (watery diarrhea).

Sandostatin substantially reduces growth hormone and/or IGF-I (somatomedin C) levels in patients with acromegaly.

Single doses of Sandostatin have been shown to inhibit gallbladder contractility and to decrease bile secretion in normal volunteers. In controlled clinical trials the incidence of gallstone or biliary sludge formation was markedly increased (see WARNINGS).

Sandostatin suppresses secretion of thyroid stimulating hormone (TSH).

NDC 63323-0376-01 UPC/GTIN No.3-63323-37601-7 Mfg.Part No.37601
RX ITEM-Octreotide 100 Mcg/Ml Vial 10X1M
NDC 63323-0376-01 UPC/GTIN No.3-63323-37601-7 Mfg.Part No.37601

BRAND: OCTREOTIDE NDC: 63323-0376-01,63323037601 UPC: 3-63323-37601-7,363323376017
Octreotide 100 Mcg/Ml Vial 10X1Ml By Fre
BRAND: OCTREOTIDE NDC: 63323-0376-01,63323037601 UPC: 3-63323-37601-7,363323376017

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
Click above for Sandostatin
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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