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Rx Item-Nortriptyline 25Mg Cap 500 By Mayne Pharma

NDC 00591-5787-05 UPC/GTIN No.3-05915-78705-4 Mfg.Part No.578705BRAND: NORTRIPTYLINE NDC: 00591-5787-05,591578705 UPC: 3-05915-78705-4,305915787054 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Nortriptyline 25Mg Cap 500 By Mayne Pharma

$717.94$820.50

Item No.:RX561761 NDC No.591578705 UPC No.:305915787054 NDC No. 51862-0016-05 UPC/GTIN No. MPN 578705 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx561761 Nortriptyline 25mg Cap 500 by Mayne Pharma Item No. 561761 NDC No. 51862001605 UPC No. Other Name Pamelor, Aventyl, Nortriptyline Therapeuti

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PAMELOR: Package Insert and Label Information
By Mallinckrodt, Inc. | Last revised: 3 February 2017
PAMELOR- nortriptyline hydrochloride capsule
Mallinckrodt, Inc.


Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of nortriptyline hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Nortriptyline hydrochloride is not approved for use in pediatric patients ( see WARNINGS, Clinical Worsening and Suicide Risk; PRECAUTIONS, Information for Patients; and PRECAUTIONS, Pediatric Use).

DESCRIPTION

Pamelor� (nortriptyline HCl) is 1-propanamine, 3-(10,11-dihydro-5H -dibenzo[a,d ] cyclohepten-5-ylidene)-N -methyl-, hydrochloride.
10 mg, 25 mg, 50 mg, and 75 mg Capsules
Active Ingredient: nortriptyline hydrochloride USP.

10 mg, 25 mg, and 75 mg Capsules
Inactive Ingredients: D&C Yellow #10, FD&C Yellow #6, gelatin, silicone fluid, starch, and titanium dioxide.

50 mg Capsules
Inactive Ingredients: gelatin, silicone fluid, starch, and titanium dioxide.

CLINICAL PHARMACOLOGY

The mechanism of mood elevation by tricyclic antidepressants is at present unknown. Pamelor is not a monoamine oxidase inhibitor. It inhibits the activity of such diverse agents as histamine, 5-hydroxytryptamine, and acetylcholine. It increases the pressor effect of norepinephrine but blocks the pressor response of phenethylamine. Studies suggest that Pamelor interferes with the transport, release, and storage of catecholamines. Operant conditioning techniques in rats and pigeons suggest that Pamelor has a combination of stimulant and depressant properties.

INDICATIONS AND USAGE

Pamelor� (nortriptyline HCl) is indicated for the relief of symptoms of depression. Endogenous depressions are more likely to be alleviated than are other depressive states.
WARNINGS

Clinical Worsening and Suicide Risk
Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide. There has been a long-standing concern, however, that antidepressants may have a role in inducing worsening of depression and the emergence of suicidality in certain patients during the early phases of treatment. Pooled analyses of short-term placebo-controlled trials of antidepressant drugs (SSRIs and others) showed that these drugs increase the risk of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults (ages 18 to 24) with major depressive disorder (MDD) and other psychiatric disorders. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction with antidepressants compared to placebo in adults aged 65 and older.

NDC 00591-5787-05 UPC/GTIN No.3-05915-78705-4 Mfg.Part No.578705
RX ITEM-Nortriptyline 25Mg Cap 500 By Ma
NDC 00591-5787-05 UPC/GTIN No.3-05915-78705-4 Mfg.Part No.578705

BRAND: NORTRIPTYLINE NDC: 00591-5787-05,591578705 UPC: 3-05915-78705-4,305915787054
Nortriptyline 25Mg Cap 500 By Mayne Phar
BRAND: NORTRIPTYLINE NDC: 00591-5787-05,591578705 UPC: 3-05915-78705-4,305915787054

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
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