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RX ITEM-Norpramin 100Mg Tab 100 By Aventis Pharma

NDC 00068-0020-01 UPC/GTIN No.3-00680-02001-6 Mfg.Part No.2001BRAND: NORPRAMIN NDC: 00068-0020-01,68002001 UPC: 3-00680-02001-6,300680020016 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Norpramin 100Mg Tab 100 By Aventis Pharma

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item No.:RX435099 NDC No.68002001 UPC No.:300680020016 NDC No. 00068-0020-01 UPC/GTIN No. 3-00680-02001-6 MPN 2001 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No. Rx435099 Norpramin 100mg Tab 100 by Aventis Pharma Item No. 3435099 NDC No. 00068002001 UPC No. 300680020016 Other Name Norpramin Therap

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NORPRAMIN- desipramine hydrochloride tablet, sugar coated
Validus Pharmaceuticals LLC


NORPRAMIN � (desipramine hydrochloride tablets USP)


Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children , adolescents , and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of NORPRAMIN or any other antidepressant in a child , adolescent , or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. NORPRAMIN is not approved for use in pediatric patients. (See WARNINGS: Clinical Worsening and Suicide Risk , PRECAUTIONS: Information for Patients , and PRECAUTIONS: Pediatric Use .)

DESCRIPTION
NORPRAMIN� (desipramine hydrochloride USP) is an antidepressant drug of the tricyclic type, and is chemically: 5H -Dibenz[b� ]azepine-5-propanamine,10,11-dihydro-N -methyl-, monohydrochloride. Inactive Ingredients The following inactive ingredients are contained in all dosage strengths: acacia, calcium carbonate, corn starch, D&C Red No. 30 and D&C Yellow No. 10 (except 10 mg and 150 mg), FD&C Blue No. 1 (except 25 mg, 75 mg, and 100 mg), hydrogenated soy oil, iron oxide, light mineral oil, magnesium stearate, mannitol, polyethylene glycol 8000, pregelatinized corn starch, sodium benzoate (except 150 mg), sucrose, talc, titanium dioxide, and other ingredients.

CLINICAL PHARMACOLOGY

Mechanism of Action
Available evidence suggests that many depressions have a biochemical basis in the form of a relative deficiency of neurotransmitters such as norepinephrine and serotonin. Norepinephrine deficiency may be associated with relatively low urinary 3-methoxy-4-hydroxyphenyl glycol (MHPG) levels, while serotonin deficiencies may be associated with low spinal fluid levels of 5-hydroxyindoleacetic acid.

While the precise mechanism of action of the tricyclic antidepressants is unknown, a leading theory suggests that they restore normal levels of neurotransmitters by blocking the re-uptake of these substances from the synapse in the central nervous system. Evidence indicates that the secondary amine tricyclic antidepressants, including NORPRAMIN, may have greater activity in blocking the re-uptake of norepinephrine. Tertiary amine tricyclic antidepressants, such as amitriptyline, may have greater effect on serotonin re-uptake.

NORPRAMIN is not a monoamine oxidase inhibitor (MAOI) and does not act primarily as a central nervous system stimulant. It has been found in some studies to have a more rapid onset of action than imipramine. Earliest therapeutic effects may occasionally be seen in 2 to 5 days, but full treatment benefit usually requires 2 to 3 weeks to obtain. Norpramin Indications and Usage

NORPRAMIN is indicated for the treatment of depression.

NDC 00068-0020-01 UPC/GTIN No.3-00680-02001-6 Mfg.Part No.2001
RX ITEM-Norpramin 100Mg Tab 100 By Avent
NDC 00068-0020-01 UPC/GTIN No.3-00680-02001-6 Mfg.Part No.2001

BRAND: NORPRAMIN NDC: 00068-0020-01,68002001 UPC: 3-00680-02001-6,300680020016
Norpramin 100Mg Tab 100 By Aventis Pharm
BRAND: NORPRAMIN NDC: 00068-0020-01,68002001 UPC: 3-00680-02001-6,300680020016

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
DESIPRAMINE HCL ORAL TABL
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.