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Rx Item-Movantik 25Mg Tab 30 By Astra Zeneca Pharma

NDC 00310-1970-30 UPC/GTIN No.3-03101-97030-3 Mfg.Part No.197030  nGL, 25
tablet , film-coated , pink , oval oblong
BiconvexDebossedBRAND: MOVANTIK NDC: 00310-1970-30,310197030 UPC: 3-03101-97030-3,303101970303 Astra Zeneca PharmaOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Movantik 25Mg Tab 30 By Astra Zeneca Pharma

$426.46$406.15

Item No.:RX377440 NDC No.310197030 UPC No.:303101970303 NDC No.00310-1970-30 UPC/GTIN No.3-03101-97030-3 MPN 197030 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No.Rx377440 Movantik 25mg Tab 30 by Astra Zeneca Pharma Item No.3377440 NDC No.00310197030 UPC No.303101970303 Other Name Movantik Therapeu

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MOVANTIK- naloxegol oxalate tablet, film coated
AstraZeneca Pharmaceuticals LP

1 INDICATIONS AND USAGE

MOVANTIK� (naloxegol) is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.

2 DOSAGE AND ADMINISTRATION

​ 2.1 Administration Instructions

Discontinue all maintenance laxative therapy prior to initiation of MOVANTIK. Laxative(s) can be used as needed if there is a suboptimal response to MOVANTIK after three days.

Alteration in analgesic dosing regimen prior to initiating MOVANTIK is not required.

MOVANTIK has been shown to be efficacious in patients who have taken opioids for at least 4 weeks. Sustained exposure to opioids prior to starting MOVANTIK may increase the patient's sensitivity to the effects of MOVANTIK [see Clinical Studies (14) ].

Take MOVANTIK on an empty stomach at least 1 hour prior to the first meal of the day or 2 hours after the meal.

For patients who are unable to swallow the MOVANTIK tablet whole, the tablet can be crushed to a powder, mixed with 4 ounces (120 mL) of water and drunk immediately. The glass should be refilled with 4 ounces (120 mL) of water, stirred and the contents drunk.

MOVANTIK can also be administered via a nasogastric (NG) tube, as follows:
1.
Flush the NG tube with 1 ounce (30 mL) of water using a 60 mL syringe.
2.
Crush the tablet to a powder in a container and mix with approximately 2 ounces (60 mL) of water.
3.
Draw up the mixture using the 60 mL syringe and administer the syringe contents through the NG tube.
4.
Add approximately 2 ounces (60 mL) of water to the same container used to prepare the dose of MOVANTIK.
5.
Draw up the water using the same 60 mL syringe and use all the water to flush the NG tube and any remaining medicine from the NG tube into the stomach.

Avoid consumption of grapefruit or grapefruit juice during treatment with MOVANTIK.

Discontinue MOVANTIK if treatment with the opioid pain medication is also discontinued.
2.2 Adult Dosage


The recommended MOVANTIK dosage is 25 mg once daily in the morning. If patients are not able to tolerate MOVANTIK, reduce the dosage to 12.5 mg once daily [see Clinical Pharmacology (12.2)].

2.3 Dosage in Adult Patients with Renal Impairment
The starting dosage for patients with creatinine clearance (CLcr) < 60 mL/min (i.e., patients with moderate, severe or end-stage renal impairment) is 12.5 mg once daily. If this dosage is well tolerated but OIC symptoms continue, the dosage may be increased to 25 mg once daily taking into consideration the potential for markedly increased exposures in some patients with renal impairment and the increased risk of adverse reactions with higher exposures [see Use in Specific Populations (8.6) and Clinical Pharmacology (12.3)].

2.4 Dosage Recommendations due to Drug Interactions
Avoid concomitant use of MOVANTIK with moderate CYP3A4 inhibitor drugs (e.g., diltiazem, erythromycin, verapamil). If concurrent use is unavoidable, reduce the MOVANTIK dosage to 12.5 mg once daily and monitor for adverse reactions [see Drug Interactions (7.1) and Clinical Pharmacology (12.3)].

3 DOSAGE FORMS AND STRENGTHS

MOVANTIK (naloxegol) is available in two strengths:


Tablets: 12.5 mg supplied as mauve, oval, biconvex, film-coated, intagliated with "nGL" on one side and "12.5" on the other side.

Tablets: 25 mg supplied as mauve, oval, biconvex, film-coated, intagliated with "nGL" on one side and "25" on the other side.

NDC 00310-1970-30 UPC/GTIN No.3-03101-97030-3 Mfg.Part No.197030  nGL, 25
tablet , film-coated , pink , oval oblong
BiconvexDebossed
RX ITEM-Movantik 25Mg Tab 30 By Astra Ze
NDC 00310-1970-30 UPC/GTIN No.3-03101-97030-3 Mfg.Part No.197030 nGL, 25 tablet , film-coated , pink , oval oblong BiconvexDebossed

BRAND: MOVANTIK NDC: 00310-1970-30,310197030 UPC: 3-03101-97030-3,303101970303 Astra Zeneca Pharma
Movantik 25Mg Tab 30 By Astra Zeneca Pha
BRAND: MOVANTIK NDC: 00310-1970-30,310197030 UPC: 3-03101-97030-3,303101970303 Astra Zeneca Pharma

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
NALOXEGOL OXALATE ORAL TA
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.