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Rx Item-Minitran 0.4Mg Hr Patch 30 By Valeant Pharma

NDC 99207-0172-10 UPC/GTIN No.3-99207-17210-9 Mfg.Part No.17210BRAND: MINITRAN NDC: 99207-0172-10,99207017210 UPC: 3-99207-17210-9,399207172109 Valeant PharmaOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Minitran 0.4Mg Hr Patch 30 By Valeant Pharma

$680.62$648.21

Item No.:RX160693 NDC No.99207017210 UPC No.:399207172109 NDC No. 99207-0172-10 UPC/GTIN No. 3-99207-17210-9 MPN 17210 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx160693 Minitran 0.4mg/Hr Patch 30 by Valeant Pharma Item No. 3160693 NDC No. 99207017210 UPC No. 399207172109 Other Name Minitran,

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MINITRAN- nitroglycerin patch
3M Pharmaceuticals

DESCRIPTION

Nitroglycerin is a 1,2,3-propanetriol trinitrate, an organic nitrate whose structural formula is

Image from Drug Label Content
and whose molecular weight is 227.09. The organic nitrates are vasodilators, active on both arteries and veins.

The MINITRAN� (nitroglycerin) Transdermal Delivery System is a unit designed to provide continuous controlled release of nitroglycerin through intact skin. The rate of release of nitroglycerin is linearly dependent upon the area of the applied system; each cm2 of applied system delivers approximately 0.03 mg of nitroglycerin per hour. Thus, the 3.3, 6.7, 13.3 and 20 cm2 system delivers approximately 0.1, 0.2, 0.4 and 0.6 mg of nitroglycerin per hour, respectively.



The remainder of the nitroglycerin in each system serves as a reservoir and is not delivered in normal use. After 12 hours, for example, each system has delivered about 14% of its original content of nitroglycerin.

The MINITRAN Transdermal Delivery System contains nitroglycerin as the active component. The remaining components of the system (acrylate copolymer adhesive, fatty acid esters, and polyethylene backing) are pharmacologically inactive. Each patch is packaged in foil/polymer film laminate.

Prior to use, a protective peel strip is removed from the adhesive surface. Following use, the patch should be discarded in a manner that prevents accidental application or ingestion by children or others.

CLINICAL PHARMACOLOGY

The principal pharmacological action of nitroglycerin is relaxation of the vascular smooth muscle and consequent dilatation of peripheral arteries and veins, especially the latter. Dilatation of the veins promotes peripheral pooling of blood and decreases venous return to the heart, thereby reducing left ventricular end-diastolic pressure and pulmonary capillary wedge pressure (preload). Arteriolar relaxation reduces systemic vascular resistance, systolic arterial pressure, and mean arterial pressure (afterload). Dilatation of the coronary arteries also occurs. The relative importance of preload reduction, afterload reduction, and coronary dilatation remains undefined.

Dosing regimens for most chronically used drugs are designed to provide plasma concentrations that are continuously greater than a minimally effective concentration. This strategy is inappropriate for organic nitrates. Several well-controlled clinical trials have used exercise testing to assess the anti-anginal efficacy of continuously-delivered nitrates. In the large majority of these trials, active agents were indistinguishable from placebo after 24 hours (or less) of continuous therapy. Attempts to overcome nitrate tolerance by dose escalation, even to doses far in excess of those used acutely, have consistently failed. Only after nitrates have been absent from the body for several hours was their anti-anginal efficacy restored. INDICATIONS AND USAGE

Transdermal nitroglycerin is indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of transdermal nitroglycerin is not sufficiently rapid for this product to be useful in aborting an acute attack.

NDC 99207-0172-10 UPC/GTIN No.3-99207-17210-9 Mfg.Part No.17210
RX ITEM-Minitran 0.4Mg Hr Patch 30 By Va
NDC 99207-0172-10 UPC/GTIN No.3-99207-17210-9 Mfg.Part No.17210

BRAND: MINITRAN NDC: 99207-0172-10,99207017210 UPC: 3-99207-17210-9,399207172109 Valeant Pharma
Minitran 0.4Mg Hr Patch 30 By Valeant Ph
BRAND: MINITRAN NDC: 99207-0172-10,99207017210 UPC: 3-99207-17210-9,399207172109 Valeant Pharma

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
NITROGLYCERIN TRANSDERM P
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.