Clinical Information
Gen. Code and Des.
52836 methscopolamine bromide ORAL TABLET 5 MG
GCN and Des.
20077 methscopolamine bromide ORAL TABLET 5 MG
Strength
5MG
Dose Form
TABLET
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family
AHFS Class
12080800 ANTIMUSCARINICS/ANTISPASMODICS
Active Ingredients
1721 methscopolamine bromide 155419
METHSCOPOLAMINE BROMIDE- methscopolamine bromide tablet
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.
DESCRIPTION
Methylscopolamine or methscopolamine, usually provided as the bromide salt (trade name Pamine), is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion.
Methscopolamine Bromide 2.5 mg Tablets/Methscopolamine Bromide 5 mg Tablets contain methscopolamine bromide, an anticholinergic, which occurs as white crystals, or as a white odorless crystalline powder. Methscopolamine bromide melts at about 225�C with decomposition. The drug is freely soluble in water, slightly soluble in alcohol, and insoluble in acetone and in chloroform.
The chemical name for methscopolamine bromide is 3-Oxa-9-azoniatricyclo [3.3.1.02,4 ] nonane, 7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9, 9-dimethyl-, bromide, [7(S)-(1?, 2?, 4?, 5? , 7?)]- and the molecular weight is 398.30. Methscopolamine Bromide 2.5 mg Tablets for oral administration contain 2.5 mg of methscopolamine bromide. Methscopolamine Bromide 5 mg Tablets for oral administration contain 5 mg of methscopolamine bromide.
Inactive ingredients: microcrystalline cellulose, pregelatinized starch, magnesium stearate.
Contains no lactose.
CLINICAL PHARMACOLOGY
Methscopolamine bromide is an anticholinergic agent which possesses most of the pharmacologic actions of that drug class. These include reduction in volume and total acid content of gastric secretion, inhibition of gastrointestinal motility, inhibition of salivary excretion, dilation of the pupil and inhibition of accommodation with resulting blurring of vision. Large doses may result in tachycardia. INDICATIONS AND USAGE
Adjunctive therapy for the treatment of peptic ulcer.
METHSCOPOLAMINE BROMIDE HAS NOT BEEN SHOWN TO BE EFFECTIVE IN CONTRIBUTING TO THE HEALING OF PEPTIC ULCER, DECREASING THE RATE OF RECURRENCE OR PREVENTING COMPLICATIONS.
