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Rx Item-Mesalamine 4 G 60 Ml Kit 28X60Ml By Perrigo Pharma

NDC 45802-0923-49 UPC/GTIN No.3-45802-92349-3 Mfg.Part No.92349BRAND: MESALAMINE NDC: 45802-0923-49,45802092349 UPC: 3-45802-92349-3,345802923493 Perrigo CoOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Mesalamine 4 G 60 Ml Kit 28X60Ml By Perrigo Pharma

$669.38$765.01

Item No.:RX025027 NDC No.45802092349 UPC No.:345802923493 NDC No. 45802-0923-49 UPC/GTIN No. 3-45802-92349-3 MPN 92349 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx025027 Mesalamine 4 G/60 ml Kit 28X60ml by Perrigo Pharma Item No. 3025027 NDC No. 45802092349 UPC No. 345802923493 Other Name Mes

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ROWASA- mesalamine enema
Alaven Pharmaceutical LLC
DESCRIPTION

The active ingredient in ROWASA� (mesalamine) Rectal Suspension Enema, a disposable (60 mL) unit, is mesalamine, also known as 5-aminosalicylic acid (5-ASA). Chemically, mesalamine is 5-amino-2-hydroxybenzoic acid.

The empirical formula is C7 H7 NO3 , representing a molecular weight of 153.14.
Each rectal suspension enema unit contains 4 grams of mesalamine. In addition to mesalamine the preparation contains the inactive ingredients carbomer 934P, edetate disodium, potassium acetate, potassium metabisulfite, purified water and xanthan gum. Sodium benzoate is added as a preservative. The disposable unit consists of an applicator tip protected by a polyethylene cover and lubricated with USP white petrolatum. The unit has a one-way valve to prevent back flow of the dispensed product.
CLINICAL PHARMACOLOGY

Sulfasalazine is split by bacterial action in the colon into sulfapyridine (SP) and mesalamine (5-ASA). It is thought that the mesalamine component is therapeutically active in ulcerative colitis [A.K. Azad Khan et al, Lancet 2:892-895 (1977)]. The usual oral dose of sulfasalazine for active ulcerative colitis in adults is two to four grams per day in divided doses. Four grams of sulfasalazine provide 1.6 g of free mesalamine to the colon. Each ROWASA� (Mesalamine) Rectal Suspension Enema delivers up to 4 g of mesalamine to the left side of the colon.


The mechanism of action of mesalamine (and sulfasalazine) is unknown, but appears to be topical rather than systemic. Mucosal production of arachidonic acid (AA) metabolites, both through the cyclooxygenase pathways, i.e., prostanoids, and through the lipoxygenase pathways, i.e., leukotrienes (LTs) and hydroxyeicosatetraenoic acids (HETEs) is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalamine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin (PG) production in the colon.
INDICATIONS AND USAGE

ROWASA� (mesalamine) Rectal Suspension Enema is indicated for the treatment of active mild to moderate distal ulcerative colitis, proctosigmoiditis or proctitis.

NDC 45802-0923-49 UPC/GTIN No.3-45802-92349-3 Mfg.Part No.92349
RX ITEM-Mesalamine 4 G 60 Ml Kit 28X60Ml
NDC 45802-0923-49 UPC/GTIN No.3-45802-92349-3 Mfg.Part No.92349

BRAND: MESALAMINE NDC: 45802-0923-49,45802092349 UPC: 3-45802-92349-3,345802923493 Perrigo Co
Mesalamine 4 G 60 Ml Kit 28X60Ml By Perr
BRAND: MESALAMINE NDC: 45802-0923-49,45802092349 UPC: 3-45802-92349-3,345802923493 Perrigo Co

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
MESALAMINE W/CLEANSING WI
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.