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RX ITEM-Macrodantin 25Mg Cap 100 By Almatica Pharma

NDC 52427-0286-01 UPC/GTIN No.3-52427-28601-8 Mfg.Part No.28601  MACRODANTIN 25 mg, 52427-286
capsule , white , oblong oblong
Black inkOpaqueBRAND: MACRODANTIN NDC: 52427-0286-01,52427028601 UPC: 3-52427-28601-8,352427286018 Almatica Pharma, IncOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Macrodantin 25Mg Cap 100 By Almatica Pharma

$1406.40$1267.17

item No.:RX128934 NDC No.52427028601 UPC No.:352427286018 NDC No. 52427-0286-01 UPC/GTIN No. 3-52427-28601-8 MPN 28601 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No. Rx128934 Macrodantin 25mg Cap 100 by Almatica Pharma Item No. 3128934 NDC No. 52427028601 UPC No. 352427286018Other Name Nitrofurant

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NITROFURANTION MACROCRYSTALS - nitrofurantoin capsule
Alvogen Inc.

nitrofurantoin-macrocrystals-25mgnitrofurantoin-macrocrystals-50mgnitrofurantoin-macrocrystals-100mg

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Nitrofurantoin Macrocrystals and other antibacterial drugs, Nitrofurantoin Macrocrystals should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DESCRIPTION
Nitrofurantoin Macrocrystals is a synthetic chemical of controlled crystal size. It is a stable, yellow, crystalline compound. Nitrofurantoin Macrocrystals is an antibacterial agent for specific urinary tract infections. It is available in 25 mg, 50 mg, and 100 mg capsules for oral administration. 1-[[(5-nitro-2-furanyl)methylene] amino]-2,4-imidazolidinedione

Inactive Ingredients: Each capsule contains edible black ink, gelatin, lactose, starch, talc, titanium dioxide, and may contain FD&C Yellow No. 6 and D&C Yellow No. 10.

CLINICAL PHARMACOLOGY

Nitrofurantoin Macrocrystals is a larger crystal form of nitrofurantoin. The absorption of Nitrofurantoin Macrocrystals is slower and its excretion somewhat less when compared to nitrofurantoin. Blood concentrations at therapeutic dosage are usually low. It is highly soluble in urine, to which it may impart a brown color.

Following a dose regimen of 100 mg q.i.d. for 7 days, average urinary drug recoveries (0-24 hours) on day 1 and day 7 were 37.9% and 35.0%.

Unlike many drugs, the presence of food or agents delaying gastric emptying can increase the bioavailability of Nitrofurantoin Macrocrystals, presumably by allowing better dissolution in gastric juices.

MICROBIOLOGY
Nitrofurantoin is a nitrofuran antimicrobial agent with activity against certain Gram-positive and Gram-negative bacteria.

Mechanism of Action
The mechanism of the antimicrobial action of nitrofurantoin is unusual among antibacterials.

Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates which inactivate or alter bacterial ribosomal proteins and other acromolecules. As a result of such inactivations, the vital biochemical processes of protein synthesis, aerobic energy metabolism, DNA synthesis, RNA synthesis, and cell wall synthesis are inhibited. Nitrofurantoin is bactericidal in urine at therapeutic doses. The broad-based nature of this mode of action may explain the lack of acquired bacterial resistance to nitrofurantoin, as the necessary multiple and simultaneous mutations of the target macromolecules would likely be lethal to the bacteria.

NDC 52427-0286-01 UPC/GTIN No.3-52427-28601-8 Mfg.Part No.28601  MACRODANTIN 25 mg, 52427-286
capsule , white , oblong oblong
Black inkOpaque
RX ITEM-Macrodantin 25Mg Cap 100 By Alma
NDC 52427-0286-01 UPC/GTIN No.3-52427-28601-8 Mfg.Part No.28601 MACRODANTIN 25 mg, 52427-286 capsule , white , oblong oblong Black inkOpaque

BRAND: MACRODANTIN NDC: 52427-0286-01,52427028601 UPC: 3-52427-28601-8,352427286018 Almatica Pharma, Inc
Macrodantin 25Mg Cap 100 By Almatica Pha
BRAND: MACRODANTIN NDC: 52427-0286-01,52427028601 UPC: 3-52427-28601-8,352427286018 Almatica Pharma, Inc

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
NITROFURANTOIN MACROCRYST
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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