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Rx Item-Latisse 0.03% Drops 5Ml By Allergan Pharma

NDC 00023-3616-05 UPC/GTIN No.3-00233-61605-5 Mfg.Part No.361605BRAND: LATISSE NDC: 00023-3616-05,23361605 UPC: 3-00233-61605-5,300233616055 Allergan USA, Inc.Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.Bimatoprost Generic Latisse

Rx Item-Latisse 0.03% Drops 5Ml By Allergan Pharma

$197.11$179.10

Item No.:RX183251 NDC No.23361605 UPC No.:300233616055 NDC No.00023-3616-05 UPC/GTIN No.3-00233-61605-5 MPN 361605 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No.Rx183251 Latisse 0.03% drops 5ml by Allergan Pharma Item No.3183251 NDC No.00023361605 UPC No.300233616055 Other Name Latisse Therapeutic

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LATISSE- bimatoprost solution/ drops
Allergan, Inc.
1 INDICATIONS AND USAGE
LATISSE � (bimatoprost ophthalmic solution) 0.03% is indicated to treat hypotrichosis of the eyelashes by increasing their growth including length, thickness and darkness.
2 DOSAGE AND ADMINISTRATION
Ensure the face is clean, makeup and contact lenses are removed. Once nightly, place one drop of LATISSE� (bimatoprost ophthalmic solution) 0.03% on the disposable sterile applicator supplied with the package and apply evenly along the skin of the upper eyelid margin at the base of the eyelashes. The upper lid margin in the area of lash growth should feel lightly moist without runoff. Blot any excess solution runoff outside the upper eyelid margin with a tissue or other absorbent cloth. Dispose of the applicator after one use. Repeat for the opposite eyelid margin using a new sterile applicator.
Do not reuse applicators and do not use any other brush/applicator to apply LATISSE �.
Do not apply to the lower eyelash line [see Warnings and Precautions (5.3, 5.4) and Patient Counseling Information (17.1)].
Additional applications of LATISSE � will not increase the growth of eyelashes.
Upon discontinuation of treatment, eyelash growth is expected to return to its pre-treatment level.
3 DOSAGE FORMS AND STRENGTHS
Bimatoprost ophthalmic solution 0.3 mg/mL.
4 CONTRAINDICATIONS
None
5 WARNINGS AND PRECAUTIONS
5.1 Effects on Intraocular Pressure
Bimatoprost ophthalmic solution (LUMIGAN �) lowers intraocular pressure (IOP) when instilled directly to the eye in patients with elevated IOP. In clinical trials, in patients with or without elevated IOP, LATISSE �lowered IOP, however, the magnitude of the reduction was not cause for clinical concern.
In ocular hypertension studies with LUMIGAN � , it has been shown that exposure of the eye to more than one dose of bimatoprost daily may decrease the intraocular pressure lowering effect. In patients using LUMIGAN � or other prostaglandin analogs for the treatment of elevated intraocular pressure, the concomitant use of LATISSE � may interfere with the desired reduction in IOP. Patients using prostaglandin analogs including LUMIGAN � for IOP reduction should only use LATISSE � after consulting with their physician and should be monitored for changes to their intraocular pressure [see Patient Counseling Information (17.3)].
5.2 Iris Pigmentation
Increased iris pigmentation has occurred when bimatoprost solution was administered. Patients should be advised about the potential for increased brown iris pigmentation which is likely to be permanent [see Adverse Reactions (6.2) and Patient Counseling Information (17.5)].
The pigmentation change is due to increased melanin content in the melanocytes rather than to an increase in the number of melanocytes. The long term effects of increased pigmentation are not known. Iris color changes seen with administration of bimatoprost ophthalmic solution may not be noticeable for several months to years. Typically, the brown pigmentation around the pupil spreads concentrically towards the periphery of the iris and the entire iris or parts of the iris become more brownish. Neither nevi nor freckles of the iris appear to be affected by treatment. Treatment with LATISSE � solution can be continued in patients who develop noticeably increased iris pigmentation.
5.3 Lid Pigmentation
Bimatoprost has been reported to cause pigment changes (darkening) to periorbital pigmented tissues and eyelashes. The pigmentation is expected to increase as long as bimatoprost is administered, but has been reported to be reversible upon discontinuation of bimatoprost in most patients [see Patient Counseling Information (17.4)].
5.4 Hair Growth Outside the Treatment Area
There is the potential for hair growth to occur in areas where LATISSE � solution comes in repeated contact with the skin surface. It is important to apply LATISSE � only to the skin of the upper eyelid margin at the base of the eyelashes using the accompanying sterile applicators, and to carefully blot any excess LATISSE � from the eyelid margin to avoid it running onto the cheek or other skin areas [see Patient Counseling Information (17.6)].
5.5 Intraocular Inflammation
LATISSE � solution should be used with caution in patients with active intraocular inflammation (e.g., uveitis) because the inflammation may be exacerbated.
5.6 Macular Edema
Macular edema, including cystoid macular edema, has been reported during treatment with bimatoprost ophthalmic solution (LUMIGAN �) for elevated IOP. LATISSE � should be used with caution in aphakic patients, in pseudophakic patients with a torn posterior lens capsule, or in patients with known risk factors for macular edema.
5.7 Contamination of LATISSE � or Applicators
The LATISSE � bottle must be kept intact during use. It is important to use LATISSE � solution as instructed, by placing one drop on the single-use-per-eye applicator. The bottle tip should not be allowed to contact any other surface since it could become contaminated. The accompanying sterile applicators should only be used on one eye and then discarded since reuse of applicators increases the potential for contamination and infections. There have been reports of bacterial keratitis associated with the use of multiple-dose containers of topical ophthalmic products [see Patient Counseling Information (17.2)].
5.8 Use with Contact Lenses
LATISSE � contains benzalkonium chloride, which may be absorbed by and cause discoloration of soft contact lenses. Contact lenses should be removed prior to application of solution and may be reinserted 15 minutes following its administration [see Patient Counseling Information (17.8)].
6 ADVERSE REACTIONS
6.1 Clinical Studies Experience
The following information is based on clinical trial results from a multicenter, double-masked, randomized, vehicle-controlled, parallel study including 278 adult patients for four months of treatment.
The most frequently reported adverse reactions were eye pruritus, conjunctival hyperemia, skin hyperpigmentation, ocular irritation, dry eye symptoms, and periorbital erythema. These reactions occurred in less than 4% of patients.
Adverse reactions reported with bimatoprost ophthalmic solution (LUMIGAN �) for the reduction of intraocular pressure include, ocular dryness, visual disturbance, ocular burning, foreign body sensation, eye pain, blepharitis, cataract, superficial punctate keratitis, eye discharge, tearing, photophobia, allergic conjunctivitis, asthenopia, increases in iris pigmentation, conjunctival edema, abnormal hair growth, iritis, infections (primarily colds and upper respiratory tract infections), headaches, and asthenia.
6.2 Postmarketing Experience
The following reactions have been identified during postmarketing use of LATISSE � in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. The reactions, which have been chosen for inclusion due to either their seriousness, frequency of reporting, possible causal connection to LATISSE � , or a combination of these factors, include: eye swelling, eyelid edema, hypersensitivity (local allergic reactions), lacrimation increased, madarosis and trichorrhexis (temporary loss of a few lashes to loss of sections of eyelashes, and temporary eyelash breakage, respectively), periorbital and lid changes associated with a deepening of the eyelid sulcus, rash (including macular and erythematous), skin discoloration (periorbital), and vision blurred.
8 USE IN SPECIFIC POPULATIONS
8.1 Pregnancy
Pregnancy Category C
DESCRIPTION
LATISSE � (bimatoprost ophthalmic solution) 0.03% is a synthetic prostaglandin analog. Its chemical name is (Z)-7-[(1R ,2R ,3R ,5S)-3,5-Dihydroxy-2-[(1E ,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N -ethyl-5-heptenamide, and its molecular weight is 415.58. Its molecular formula is C25 H37 NO4 .
imatoprost is a powder, which is very soluble in ethyl alcohol and methyl alcohol and slightly soluble in water. LATISSE � is a clear, isotonic, colorless, sterile ophthalmic solution with an osmolality of approximately 290 mOsmol/kg.
Contains: Active: bimatoprost 0.3 mg/mL; Preservative: benzalkonium chloride 0.05 mg/mL; Inactives: sodium chloride; sodium phosphate, dibasic; citric acid; and purified water. Sodium hydroxide and/or hydrochloric acid may be added to adjust pH. The pH during its shelf life ranges from 6.8 - 7.8.
12 CLINICAL PHARMACOLOGY
12.1 Mechanism of Action
Bimatoprost is a structural prostaglandin analog. Although the precise mechanism of action is unknown the growth of eyelashes is believed to occur by increasing the percent of hairs in, and the duration of the anagen or growth phase.

NDC 00023-3616-05 UPC/GTIN No.3-00233-61605-5 Mfg.Part No.361605
RX ITEM-Latisse 0.03% Drops 5Ml By Aller
NDC 00023-3616-05 UPC/GTIN No.3-00233-61605-5 Mfg.Part No.361605

BRAND: LATISSE NDC: 00023-3616-05,23361605 UPC: 3-00233-61605-5,300233616055 Allergan USA, Inc.
Latisse 0.03% Drops 5Ml By Allergan Phar
BRAND: LATISSE NDC: 00023-3616-05,23361605 UPC: 3-00233-61605-5,300233616055 Allergan USA, Inc.

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
BIMATOPROST TOPICAL DROP
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Bimatoprost Generic Latisse
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Bimatoprost Generic Latisse