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Rx Item-Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma)

Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma) item No.:RX4716252  NDC No.10122-0620-10 10122-620-10 10122062010 1012262010 1012206201	 UPC No.:310122620100 310122-620100 NDC No. new BRAND: KENGREAL NDC: 10122-0620-10 	,10122062010 	 UPC: 310122-620100,310122620100 Medicines CompanyOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma) item No.:RX4716252  NDC No.10122-0620-10 10122-620-10 10122062010 1012262010 1012206201	 UPC No.:310122620100 310122-620100 NDC No. new

Rx Item-Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma)

$10703.90$9621.00

RX716252 716252 Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma) Item No.:RX4716252 NDC No.10122-0620-10 10122-620-10 10122062010 1012262010 1012206201 UPC No.:310122620100 310122-620100 NDC No. new 10122-0620-10 10122-620-10 65293-0003-10 UPC/GTIN No. 3-10122-62010-0 MPN 206201 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of

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Clinical Information
Gen. Code and Des.
74329 cangrelor tetrasodium INTRAVEN VIAL 50 MG
GCN and Des.
38946 cangrelor tetrasodium INTRAVEN VIAL 50 MG
Strength
50MG
Dose Form
VIAL (EA)
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
20121800 PLATELET-AGGREGATION INHIBITORS
Active Ingredients
16205 cangrelor tetrasodium 163706363
Inactive Ingredients
2272 mannitol 69658
2599 sorbitol 50704






For: Percutaneous Coronary Intervention

Kengreal (cangrelor) is an intravenous P2Y12 platelet inhibitor indicated for use in patients undergoing Percutaneous Coronary Intervention (PCI) to reduce the risk of periprocedural thrombotic events. KENGREAL- cangrelor injection, powder, lyophilized, for solution
The Medicines Company

1 INDICATIONS AND USAGE

KENGREAL is indicated as an adjunct to percutaneous coronary intervention (PCI) to reduce the risk of periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST) in patients who have not been treated with a P2Y12 platelet inhibitor and are not being given a glycoprotein IIb/IIIa inhibitor [see Clinical Studies ( 14.1)].

2 DOSAGE AND ADMINISTRATION

2.1 Recommended Dosing


The recommended dosage of KENGREAL is a 30 mcg/kg IV bolus followed immediately by a 4 mcg/kg/min IV infusion. Initiate the bolus infusion prior to PCI. The maintenance infusion should ordinarily be continued for at least 2 hours or for the duration of PCI, whichever is longer.

2.2 Transitioning Patients to Oral P2Y 12 Therapy
To maintain platelet inhibition after discontinuation of KENGREAL infusion, an oral P2Y12 platelet inhibitor should be administered. Administer one as described below:

Ticagrelor: 180 mg at any time during KENGREAL infusion or immediately after discontinuation [see Clinical Pharmacology ( 12.2)].
Prasugrel: 60 mg immediately after discontinuation of KENGREAL. Do not administer prasugrel prior to discontinuation of KENGREAL [see Drug Interactions ( 7.1) and Clinical Pharmacology ( 12.2)].
Clopidogrel: 600 mg immediately after discontinuation of KENGREAL. Do not administer clopidogrel prior to discontinuation of KENGREAL [see Drug Interactions ( 7.1) and Clinical Pharmacology ( 12.2)].
2.3 Preparation and Administration
KENGREAL is intended for IV administration, after reconstitution and dilution.

Preparation

For each 50 mg/vial, reconstitute by adding 5 mL of Sterile Water for Injection. Swirl gently until all material is dissolved. Avoid vigorous mixing. Allow any foam to settle. Ensure that the contents of the vial are fully dissolved and the reconstituted material is a clear, colorless to pale yellow solution. Reconstitute the vial prior to dilution in a bag. Parenteral drug products should be inspected visually for particulate matter after reconstitution.

Do not use without dilution. Before administration, each reconstituted vial must be diluted further with Normal Saline (Sodium Chloride Injection 0.9% USP) or 5% Dextrose Injection USP.

Withdraw the contents from one reconstituted vial and add to one 250 mL saline bag. Mix the bag thoroughly. This dilution will result in a concentration of 200 mcg/mL and should be sufficient for at least 2 hours of dosing. Patients 100 kg and over will require a minimum of 2 bags.

Reconstituted KENGREAL should be diluted immediately. Diluted KENGREAL is stable for up to 12 hours in 5% Dextrose Injection and 24 hours in Normal Saline at Room Temperature. Discard any unused portion of reconstituted solution remaining in the vial.

Administration

Administer KENGREAL via a dedicated IV line.

Administer the bolus volume rapidly (<1 minute), from the diluted bag via manual IV push or pump. Ensure the bolus is completely administered before the start of PCI. Start the infusion immediately after administration of the bolus [see Dosage and Administration ( 2.1)].

3 DOSAGE FORMS AND STRENGTHS

For Injection: 50 mg of KENGREAL lyophilized powder in a single-use 10 mL glass vial for reconstitution.

Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma) item No.:RX4716252  NDC No.10122-0620-10 10122-620-10 10122062010 1012262010 1012206201	 UPC No.:310122620100 310122-620100 NDC No. new
Kengreal CANGRELOR
Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma) item No.:RX4716252 NDC No.10122-0620-10 10122-620-10 10122062010 1012262010 1012206201 UPC No.:310122620100 310122-620100 NDC No. new

BRAND: KENGREAL NDC: 10122-0620-10 	,10122062010 	 UPC: 310122-620100,310122620100 Medicines Company
Kengreal 50Mg Vial 10 By Medicines Co.(C
BRAND: KENGREAL NDC: 10122-0620-10 ,10122062010 UPC: 310122-620100,310122620100 Medicines Company

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
CANGRELOR TETRASODIUM INT
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma) item No.:RX4716252  NDC No.10122-0620-10 10122-620-10 10122062010 1012262010 1012206201	 UPC No.:310122620100 310122-620100 NDC No. new
RX ITEM-Kengreal 50Mg Vial 10 By Medicin
Kengreal CANGRELOR 50Mg Vial 10 By Medicines Co.(Chiesi Pharma) item No.:RX4716252 NDC No.10122-0620-10 10122-620-10 10122062010 1012262010 1012206201 UPC No.:310122620100 310122-620100 NDC No. new