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RX ITEM-Kadcyla 100Mg Vial 1 By Genentech

NDC 50242-0088-01 UPC/GTIN No.3-50242-08801-5 Mfg.Part No.8801BRAND: KADCYLA  NDC: 50242-0088-01,50242008801 UPC: 3-50242-08801-5,350242088015 Genentech, Inc. USAOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

RX ITEM-Kadcyla 100Mg Vial 1 By Genentech

$3585.49$3399.00

item No.:RX213900 NDC No.50242008801 UPC No.:350242088015 NDC No. 50242-0088-01 UPC/GTIN No. 3-50242-08801-5 MPN 8801 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No. Rx213900 Kadcyla 100mg Vial 1 by Genentech Item No. 3213900 NDC No. 50242008801 UPC No. 350242088015 Other Name Kadcyla, trastuzumab

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KADCYLA- ado-trastuzumab emtansine injection, powder, lyophilized, for solution
Genentech, Inc.

WARNING: HEPATOTOXICITY, CARDIAC TOXICITY, EMBRYO-FETAL TOXICITY
Do Not Substitute KADCYLA for or with trastuzumab. (2.1)
Hepatotoxicity: Serious hepatotoxicity has been reported, including liver failure and death in patients treated with KADCYLA. Monitor serum transaminases and bilirubin prior to initiation of KADCYLA treatment and prior to each KADCYLA dose. Reduce dose or discontinue KADCYLA as appropriate in cases of increased serum transaminases or total bilirubin. (2.2, 5.1)
Cardiac Toxicity: KADCYLA administration may lead to reductions in left ventricular ejection fraction (LVEF). Evaluate left ventricular function in all patients prior to and during treatment with KADCYLA. Withhold treatment for clinically significant decrease in left ventricular function. (2.2, 5.2)
? Embryo-Fetal Toxicity: Exposure to KADCYLA during pregnancy can result in embryo-fetal harm. Advise patients of these risks and the need for effective contraception (5.3, 8.1, 8.3).
1 INDICATIONS AND USAGE



KADCYLA ® , as a single agent, is indicated for the treatment of patients with HER2-positive, metastatic breast cancer who previously received trastuzumab and a taxane, separately or in combination. Patients should have either:

Received prior therapy for metastatic disease, or
Developed disease recurrence during or within six months of completing adjuvant therapy.
2 DOSAGE AND ADMINISTRATION

2.1 Recommended Doses and Schedules
The recommended dose of KADCYLA is 3.6 mg/kg given as an intravenous infusion every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity. Do not administer KADCYLA at doses greater than 3.6 mg/kg. Do not substitute KADCYLA for or with trastuzumab.

Closely monitor the infusion site for possible subcutaneous infiltration during drug administration [see Warnings and Precautions (5.10)].

First infusion: Administer infusion over 90 minutes. Patients should be observed during the infusion and for at least 90 minutes following the initial dose for fever, chills, or other infusion-related reactions [see Warnings and Precautions (5.5)].

Subsequent infusions: Administer over 30 minutes if prior infusions were well tolerated. Patients should be observed during the infusion and for at least 30 minutes after infusion.

NDC 50242-0088-01 UPC/GTIN No.3-50242-08801-5 Mfg.Part No.8801
RX ITEM-Kadcyla 100Mg Vial 1 By Genentec
NDC 50242-0088-01 UPC/GTIN No.3-50242-08801-5 Mfg.Part No.8801

BRAND: KADCYLA  NDC: 50242-0088-01,50242008801 UPC: 3-50242-08801-5,350242088015 Genentech, Inc. USA
Kadcyla 100Mg Vial 1 By Genentech
BRAND: KADCYLA NDC: 50242-0088-01,50242008801 UPC: 3-50242-08801-5,350242088015 Genentech, Inc. USA

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
ADO-TRASTUZUMAB EMTANSINE
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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