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Rx Item-Imuran 50Mg Tab 100 By Prometheus

NDC 65483-0590-10 UPC/GTIN No.3-65483-59010-4 Mfg.Part No.59010BRAND: IMURAN NDC: 65483-0590-10,65483059010 UPC: 3-65483-59010-4,365483590104 Prometheus PharmaOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Imuran 50Mg Tab 100 By Prometheus

$1124.34$803.10

Item No.:RX149542 NDC No.65483059010 UPC No.:365483590104 NDC No. 65483-0590-10 UPC/GTIN No. 3-65483-59010-4 MPN 59010 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx149542 Imuran 50mg Tab 100 by Prometheus Item No. 3149542 NDC No. 65483059010 UPC No. 365483590104 Other Name azathioprine tablet

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IMURAN- azathioprine tablet
Prometheus Laboratories Inc.

PRODUCT INFORMATION
Rx only

WARNING - MALIGNANCY

Chronic immunosuppression with IMURAN, a purine antimetabolite increases risk of malignancy in humans. Reports of malignancy include post-transplant lymphoma and hepatosplenic T-cell lymphoma (HSTCL) in patients with inflammatory bowel disease. Physicians using this drug should be very familiar with this risk as well as with the mutagenic potential to both men and women and with possible hematologic toxicities. Physicians should inform patients of the risk of malignancy with IMURAN. See WARNINGS.

DESCRIPTION:



IMURAN (azathioprine), an immunosuppressive antimetabolite, is available in tablet form for oral administration. Each scored tablet contains 50 mg azathioprine and the inactive ingredients lactose, magnesium stearate, potato starch, povidone, and stearic acid.

Azathioprine is chemically 6-[(1-methyl-4-nitro-1H -imidazol-5-yl)thio]-1H -purine. The structural formula of azathioprine is:

Structural Formula
It is an imidazolyl derivative of 6-mercaptopurine and many of its biological effects are similar to those of the parent compound.

Azathioprine is insoluble in water, but may be dissolved with addition of one molar equivalent of alkali. Azathioprine is stable in solution at neutral or acid pH but hydrolysis to mercaptopurine occurs in excess sodium hydroxide (0.1N), especially on warming. Conversion to mercaptopurine also occurs in the presence of sulfhydryl compounds such as cysteine, glutathione, and hydrogen sulfide.

CLINICAL PHARMACOLOGY:

Azathioprine is well absorbed following oral administration. Maximum serum radioactivity occurs at 1 to 2 hours after oral 35 S-azathioprine and decays with a half-life of 5 hours. This is not an estimate of the half-life of azathioprine itself, but is the decay rate for all 35 S-containing metabolites of the drug. Because of extensive metabolism, only a fraction of the radioactivity is present as azathioprine. Usual doses produce blood levels of azathioprine, and of mercaptopurine derived from it, which are low (<1 mcg/mL). Blood levels are of little predictive value for therapy since the magnitude and duration of clinical effects correlate with thiopurine nucleotide levels in tissues rather than with plasma drug levels. Azathioprine and mercaptopurine are moderately bound to serum proteins (30%) and are partially dialyzable. See OVERDOSAGE.

NDC 65483-0590-10 UPC/GTIN No.3-65483-59010-4 Mfg.Part No.59010
RX ITEM-Imuran 50Mg Tab 100 By Prometheu
NDC 65483-0590-10 UPC/GTIN No.3-65483-59010-4 Mfg.Part No.59010

BRAND: IMURAN NDC: 65483-0590-10,65483059010 UPC: 3-65483-59010-4,365483590104 Prometheus Pharma
Imuran 50Mg Tab 100 By Prometheus
BRAND: IMURAN NDC: 65483-0590-10,65483059010 UPC: 3-65483-59010-4,365483590104 Prometheus Pharma

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
AZATHIOPRINE ORAL TABLET
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.