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Rx Item-Idarubicin 1Mg/Ml Vial 5Ml By Teva Pharma

NDC 00703-4154-11 UPC/GTIN No.3-07034-15411-3 Mfg.Part No.415411BRAND: IDARUBICIN NDC: 00703-4154-11,703415411 UPC: 3-07034-15411-3,307034154113 Teva Pharmaceuticals USAOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Idarubicin 1Mg/Ml Vial 5Ml By Teva Pharma

$98.82$94.11

Item No.:RX669155 NDC No.703415411 UPC No.:307034154113 NDC No. 00703-4154-11 UPC/GTIN No. 3-07034-15411-3 MPN 415411 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx669155 Idarubicin 1mg/ml Vial 5ml by Teva Pharma Item No. 3669155 NDC No. 703415411 UPC No. 307034154113 Other Name Idamycin,Ida

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IDARUBICIN HYDROCHLORIDE- idarubicin hydrochloride injection
Sandoz Inc

Rx only

FOR INTRAVENOUS USE ONLY

WARNINGS

1. Idarubicin Hydrochloride Injection should be given slowly into a freely flowing intravenous infusion. It must never be given intramuscularly or subcutaneously. Severe local tissue necrosis can occur if there is extravasation during administration.

2. As is the case with other anthracyclines the use of Idarubicin Hydrochloride Injection can cause myocardial toxicity leading to congestive heart failure. Cardiac toxicity is more common in patients who have received prior anthracyclines or who have pre-existing cardiac disease.



3. As is usual with antileukemic agents, severe myelosuppression occurs when Idarubicin Hydrochloride Injection is used at effective therapeutic doses.

4. It is recommended that Idarubicin Hydrochloride Injection be administered only under the supervision of a physician who is experienced in leukemia chemotherapy and in facilities with laboratory and supportive resources adequate to monitor drug tolerance and protect and maintain a patient compromised by drug toxicity. The physician and institution must be capable of responding rapidly and completely to severe hemorrhagic conditions and/or overwhelming infection.

5. Dosage should be reduced in patients with impaired hepatic or renal function. (See DOSAGE AND ADMINISTRATION.)

DESCRIPTION

Idarubicin Hydrochloride Injection contains idarubicin hydrochloride and is a sterile, semi-synthetic, preservative-free solution antineoplastic anthracycline for intravenous use. Chemically, idarubicin hydrochloride is 5, 12- Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-� -L-lyxo -hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxyhydrochloride, (7S-cis). The structural formula is as follows:

structrual formula
(click image for full-size original)
Idarubicin Hydrochloride Injection is a sterile, red-orange, isotonic parenteral preservative-free solution, available in 5 mL (5 mg), 10 mL (10 mg) and 20 mL (20 mg) single-use-only vials.

Each mL contains Idarubicin HCl, USP 1 mg and the following inactive ingredients: Glycerin, USP 25 mg and Water for Injection, USP q.s. Hydrochloric Acid, NF and Sodium Hydroxide, NF are used to adjust the pH to a target of 3.5.

CLINICAL PHARMACOLOGY

Mechanism of Action

Idarubicin hydrochloride is a DNA-intercalating analog of daunorubicin which has an inhibitory effect on nucleic acid synthesis and interacts with the enzyme topoisomerase II. The absence of a methoxy group at position 4 of the anthracycline structure gives the compound a high lipophilicity which results in an increased rate of cellular uptake compared with other anthracyclines.

NDC 00703-4154-11 UPC/GTIN No.3-07034-15411-3 Mfg.Part No.415411
RX ITEM-Idarubicin 1Mg/Ml Vial 5Ml By Te
NDC 00703-4154-11 UPC/GTIN No.3-07034-15411-3 Mfg.Part No.415411

BRAND: IDARUBICIN NDC: 00703-4154-11,703415411 UPC: 3-07034-15411-3,307034154113 Teva Pharmaceuticals USA
Idarubicin 1Mg/Ml Vial 5Ml By Teva Pharm
BRAND: IDARUBICIN NDC: 00703-4154-11,703415411 UPC: 3-07034-15411-3,307034154113 Teva Pharmaceuticals USA

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
IDARUBICIN HCL INTRAVEN V
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.